Results 111 to 120 of about 4,230,112 (339)

Infrared laser sampling of low volumes combined with shotgun lipidomics reveals lipid markers in palatine tonsil carcinoma

open access: yesMolecular Oncology, EarlyView.
Nanosecond infrared laser (NIRL) low‐volume sampling combined with shotgun lipidomics uncovers distinct lipidome alterations in oropharyngeal squamous cell carcinoma (OPSCC) of the palatine tonsil. Several lipid species consistently differentiate tumor from healthy tissue, highlighting their potential as diagnostic markers.
Leonard Kerkhoff   +11 more
wiley   +1 more source

3D head tracking using normal flow constraints in a vehicle environment [PDF]

open access: yes, 2007
Head tracking is a key component in applications such as human computer interaction, person monitoring, driver monitoring, video conferencing, and object-based compression.
Akan, Batu   +4 more
core  

Correlation of the differential expression of PIK3R1 and its spliced variant, p55α, in pan‐cancer

open access: yesMolecular Oncology, EarlyView.
PIK3R1 undergoes alternative splicing to generate the isoforms, p85α and p55α. By combining large patient datasets with laboratory experiments, we show that PIK3R1 spliced variants shape cancer behavior. While tumors lose the protective p85α isoform, p55α is overexpressed, changes linked to poorer survival and more pronounced in African American ...
Ishita Gupta   +10 more
wiley   +1 more source

The Neutrality of the Romanian Head of State

open access: yesBulletin of the Transilvania University of Braşov: Series VII: Social Sciences, Law
The Constitution of Romania, republished, expressly enshrines, in art. 1 para (4), the principle of separation and balance of powers in the state. The possibility of respecting this principle is outlined by constitutional provisions relating to public ...
Oana Saramet
doaj   +1 more source

Blast-Induced Tinnitus and Elevated Central Auditory and Limbic Activity in Rats: A Manganese-Enhanced MRI and Behavioral Study

open access: yesScientific Reports, 2017
Blast-induced tinitus is the number one service-connected disability that currently affects military personnel and veterans. To elucidate its underlying mechanisms, we subjected 13 Sprague Dawley adult rats to unilateral 14 psi blast exposure to induce ...
Jessica Ouyang   +6 more
doaj   +1 more source

Basroparib inhibits YAP‐driven cancers by stabilizing angiomotin

open access: yesMolecular Oncology, EarlyView.
Basroparib, a selective tankyrase inhibitor, suppresses Wnt signaling and attenuates YAP‐driven oncogenic programs by stabilizing angiomotin. It promotes AMOT–YAP complex formation, enforces cytoplasmic YAP sequestration, inhibits YAP/TEAD transcription, and sensitizes YAP‐active cancers, including KRAS‐mutant colorectal cancer, to MEK inhibition.
Young‐Ju Kwon   +4 more
wiley   +1 more source

Does central tympanic membrane perforation affect infrared tympanic thermometer measurements in adults?

open access: yesJournal of Otology, 2018
Objective: Infrared Tympanic Thermometer (ITT) is one of the most useful instruments for accurately measuring temperature. The effects of ear pathologies on ITT measurement remain unclear.
Hamdi Tasli, Mert Cemal Gökgöz
doaj   +1 more source

Colorectal cancer‐derived FGF19 is a metabolically active serum biomarker that exerts enteroendocrine effects on mouse liver

open access: yesMolecular Oncology, EarlyView.
Meta‐transcriptome analysis identified FGF19 as a peptide enteroendocrine hormone associated with colorectal cancer prognosis. In vivo xenograft models showed release of FGF19 into the blood at levels that correlated with tumor volumes. Tumoral‐FGF19 altered murine liver metabolism through FGFR4, thereby reducing bile acid synthesis and increasing ...
Jordan M. Beardsley   +5 more
wiley   +1 more source

Thermoneutral housing temperature regulates T-regulatory cell function and inhibits ovabumin-induced asthma development in mice

open access: yesScientific Reports, 2017
The change in ambient temperature is one of the risk factors for the aggravation of bronchial asthma (BA). Yet, whether the ambient temperature influences the immune functions associated with allergic asthma remains unknown.
Wenjing Liao   +8 more
doaj   +1 more source

Heads of State and Government [PDF]

open access: yes, 1985
Macmillan published the first edition of this text in 1985. It is a detailed reference to world leaders, monarchs, presidents and their equivalents, executive leaders plus other positions with authority vested in them heads of ruling communist parties, military junta heads and some leaders with no formal post, but who wield supreme authority.
openaire   +1 more source

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