Results 1 to 10 of about 69,246 (125)

Early and Delayed Rebound Intracranial Hypertension following Epidural Blood Patch in a Case of Spontaneous Intracranial Hypotension

Case Reports in Neurological Medicine, 2022
Background. Spontaneous intracranial hypotension (SIH) is a secondary headache that has been attributed to a cerebrospinal fluid (CSF) leak. It may resolve spontaneously or require conservative treatment.
Elham Jafari, Maryam Karaminia, Mansoureh Togha   +2 more
doaj   +1 more source

Psychological predictors of negative treatment outcome with Erenumab in chronic migraine: data from an open label long-term prospective study

The Journal of Headache and Pain, 2021
Background Monoclonal antibodies (mABs) targeting the calcitonin gene-related peptide (CGRP) pathway represent the first disease-specific preventive migraine therapy.
Bottiroli Sara, Roberto De Icco, Gloria Vaghi, Stefania Pazzi, Elena Guaschino, Marta Allena, Natascia Ghiotto, Daniele Martinelli, Cristina Tassorelli, Grazia Sances   +9 more
doaj   +1 more source

Six-month therapy of CGRP monoclonal antibodies in real-world clinical practice: an interim analysis of efficacy and safety data

Медицинский совет, 2022
Introduction. Migraine is one of the most common disabling neurological disorders. Recently developed monoclonal antibodies to calcitonin gene-related peptide (CGRP) or its receptor are the first targeted medication for preventive therapy of both ...
N. V. Vashchenko, A. M. Uzhakhov, M. V. Bogorodskaya, D. Z. Korobkova, Ju. E. Azimova, K. V. Skorobogatykh   +5 more
doaj   +1 more source

Plasma levels of CGRP and expression of specific microRNAs in blood cells of episodic and chronic migraine subjects: towards the identification of a panel of peripheral biomarkers of migraine?

The Journal of Headache and Pain, 2020
Background Migraine can manifest with an episodic or a chronic pattern in a continuum of disease severity. Multiple factors are associated with the progression of the pattern from episodic to chronic.
Rosaria Greco, Roberto De Icco, Chiara Demartini, Anna Maria Zanaboni, Elena Tumelero, Grazia Sances, Marta Allena, Cristina Tassorelli   +7 more
doaj   +1 more source

Results of a Web-based survey of 2105 Greek migraine patients in 2020: demographics, clinical characteristics, burden and the effects of the COVID-19 pandemic on the course of migraine

BMC Neurology, 2022
The Greek Society of Migraine and Headache Patients (GSMHP), maintaining a strong commitment to research and information, conducted its second web-based online survey named "Migraine in Greece—2020", following its first one conducted in 2018.
Emmanouil V. Dermitzakis, Aikaterini Kouroudi, Andreas A. Argyriou, Konstantinos C. Spingos, Konstantinos Bilias, Michail Vikelis   +5 more
doaj   +1 more source

Trajectory of blood pressure after initiating anti-calcitonin gene-related peptide treatment of migraine: a target trial emulation from the veterans health administration

The Journal of Headache and Pain, 2023
Background Calcitonin gene-related peptide (CGRP) is involved in migraine pathophysiology and blood pressure regulation. Although clinical trials have established the cardio-cerebrovascular safety profile of anti-CGRP treatment, limited high-quality real-
Kaicheng Wang, Brenda T. Fenton, Vinh X. Dao, Alexander B. Guirguis, Sarah E. Anthony, Melissa Skanderson, Jason J. Sico   +6 more
doaj   +1 more source

Calcitonin gene-related peptide causes migraine aura

The Journal of Headache and Pain, 2023
Background Although the involvement of calcitonin gene-related peptide (CGRP) in migraines is well-established, its specific role in investigating the aura phase, which often precedes the headache, remains largely unexplored. This study aims to instigate
Haidar M. Al-Khazali, Håkan Ashina, Astrid Wiggers, Kathrine Rose, Afrim Iljazi, Rune Häckert Christensen, Henrik Winther Schytz, Faisal Mohammad Amin, Messoud Ashina   +8 more
doaj   +1 more source

Mapping brain functional networks topological characteristics in new daily persistent headache: a magnetoencephalography study

The Journal of Headache and Pain, 2023
Background The brain functional network topology in new daily persistent headache (NDPH) is not well understood. In this study, we aim to assess the cortical functional network topological characteristics of NDPH using non-invasive neural signal ...
Dong Qiu, Zhaoli Ge, Yanliang Mei, Wei Wang, Zhonghua Xiong, Xiaoshuang Li, Ziyu Yuan, Peng Zhang, Mantian Zhang, Xin Liu, Yaqing Zhang, Xueying Yu, Hefei Tang, Yonggang Wang   +13 more
doaj   +1 more source

Pain sensitivity in men who have never experienced a headache: an observer blinded case control study

The Journal of Headache and Pain, 2021
Background Headache affects 90–99% of the population. Based on the question “Do you think that you never ever in your whole life have had a headache?” 4% of the population say that they have never experienced a headache.
Isa Amalie Olofsson, Jeppe Hvedstrup, Katrine Falkenberg, Mona Ameri Chalmer, Henrik Winther Schytz, Miguel Benjamin Pedersen, Henrik Ullum, Ole Birger Pedersen, Jes Olesen, Thomas Folkmann Hansen   +9 more
doaj   +1 more source

The Registry for Migraine (REFORM) study: methodology, demographics, and baseline clinical characteristics

The Journal of Headache and Pain, 2023
Background Erenumab has demonstrated effectiveness for prevention of migraine attacks, but the treatment is costly, and a considerable proportion of patients do not respond to it.
William Kristian Karlsson, Håkan Ashina, Christopher Kjær Cullum, Rune Häckert Christensen, Haidar Muhsen Al-Khazali, Faisal Mohammad Amin, Messoud Ashina, on behalf of the REFORM Investigators   +7 more
doaj   +1 more source