Results 101 to 110 of about 178,854 (308)

Medication-overuse headache in patients with cluster headache [PDF]

, 2008
Cluster headache (CH) is associated with the most severe pain of the primary headache disorders. Barriers to optimal care include misdiagnosis, diagnostic delay, undertreatment, and mismanagement.
Paemeleire, KoenGE33UZGent8010010222940000-0001-8103-3899F4EB82BC-F0ED-11E1-A9DE-61C894A0A6B4, Goadsby, Peter J, Evers, Stefan, Paemeleire, Koen   +3 more
core   +1 more source

A Novel IDO1/NE Dual Inhibitor, IMM‐H018 Prevents the Primary and Secondary Sepsis and Ameliorates the Kidney Injury Through Inhibiting the Cytokine Storm and Microthrombosis, and Reversing Immunosuppression

Advanced Science, EarlyView.
IMM‐H018, a dual IDO1/NE inhibitor, demonstrates potent therapeutic efficacy in sepsis by simultaneously targeting excessive inflammation and immune dysfunction. It prevents both primary and secondary sepsis through anti‐inflammatory, immune‐restoring, and renoprotective mechanisms, reducing organ damage, improving immune homeostasis, preserving kidney
Yi Zhou, Xiaodi Zhao, Xiaochen Pan, Zhiling Ma, Huaqing Cui, Hui Wen, Peng Wang, Xiufeng Liao, Kejie Qin, Yuchen Wang, Li Sheng, Sen Zhang   +11 more
wiley   +1 more source

Headache, anxiety and depressive disorders: the HADAS study. J Headache Pain [PDF]

, 2010
Headache, anxiety and depressive disorders: the HADAS study J Headache Pain (2010) 11:141–150 Ettore Beghi • Gennaro Bussone • Domenico D’Amico • Pietro Cortelli • Sabina Cevoli • Gian Camillo Manzoni • Paola Torelli • Maria Clara Tonini • Giovanni ...
Beghi M, Cevoli S, Moschiano F, Tonini MC, D'Amico D, D'Onofrio F, Torelli P, Allais G, Salvi S., Manzoni GC, Cortelli P, Beghi E, Bussone G, Genco S, DE SIMONE, ROBERTO   +14 more
core  

Chronic Tension-Type Headache [PDF]

, 2014
A 42-year-old woman was admitted to the emergency room (ER) for the worsening of a continuous headache. She reported of having very frequent headaches for the last couple of years. Last year she had had headaches every day.
Necdet Karli, Karlı, Necdet, Zarifoğlu, Mehmet, Mehmet Zarifoğlu   +3 more
core   +1 more source

Polydopamine Nanoparticle‐Mediated Precise Near‐Infrared Optical Stimulation for Cognitive Enhancement

Advanced Science, EarlyView.
Polydopamine nanoparticles enable a precise, non‐genetic, and transcranial neuromodulation strategy via near‐infrared photothermal stimulation. By activating TRPV1 channels, this approach specifically enhances hippocampal gamma oscillations, thereby rescuing spatial memory deficits in models of perioperative neurocognitive disorder.
Yan‐Bo Zhou, Qiong Xue, Su‐Xuan Hou, Ke‐Yao Zhang, Wei‐Tong Pan, Ting‐Ting Zeng, Yu‐Ge Wang, Daqing Ma, Chenguang Zhao, Pan‐Miao Liu, Jian‐Jun Yang   +10 more
wiley   +1 more source

Gaussian Process Regression–Neural Network Hybrid with Optimized Redundant Coordinates: A New Simple Yet Potent Tool for Scientist's Machine Learning Toolbox

Advanced Intelligent Discovery, EarlyView.
A machine learning method, opt‐GPRNN, is presented that combines the advantages of neural networks and kernel regressions. It is based on additive GPR in optimized redundant coordinates and allows building a representation of the target with a small number of terms while avoiding overfitting when the number of terms is larger than optimal.
Sergei Manzhos, Manabu Ihara
wiley   +1 more source

The rain feels different under the same umbrella: Experiences with poverty across LGBTQ subgroups

American Journal of Community Psychology, EarlyView.
Abstract Population‐based survey data have demonstrated that LGBTQ communities report varying rates of economic insecurity, yet very little research directly assesses how pathways into and experiences with poverty look different among subgroups at the intersections of sexual orientation and gender identity (SOGI).
Bianca D. M. Wilson, Lillian Nguyen
wiley   +1 more source

Epigenetic DNA methylation changes associated with headache chronification : A retrospective case-control study [PDF]

, 2018
Background The biological mechanisms of headache chronification are poorly understood. We aimed to identify changes in DNA methylation associated with the transformation from episodic to chronic headache.
Int Headache Genetics Consortium
core   +1 more source

Causal proteomic insights into drug target discovery for tension-type headache

The Journal of Headache and Pain
Background The pathophysiology of tension-type headache (TTH) remains poorly understood, and current treatments are largely symptomatic. Identifying genetically supported, causally relevant proteins may provide insights into disease mechanisms and enable
Ran Gao, Renxi Wang, Zhonghua Xiong
doaj   +1 more source

B/ordering and healthcare access for migrants with precarious status: The role of healthcare workers in counteracting restrictive policies

American Journal of Community Psychology, EarlyView.
Abstract In Canada, precarious migration is largely invisibilized. Nonetheless, b/ordering greatly affects people's realities by limiting access to social rights. In Quebec, migrants with precarious status (MPS) do not have access to healthcare, although Quebec has a “universal” healthcare coverage.
Émilie Pigeon‐Gagné, Jill Hanley, Élise Bourgeois‐Guérin, Pénélope Boudreault   +3 more
wiley   +1 more source