Results 281 to 290 of about 4,421,151 (391)

Acupuncture in intractable epilepsy: lack of effect on health-related quality of life

, 2000
Knut Stavem, Robert Kloster, Edna Røssberg, Pål G. Larsson, Renate Dahl, Einar Kinge, Rasmus Lossius, Karl O. Nakken   +7 more
openalex   +1 more source

Nicotinamide N‐methyltransferase promotes drug resistance in lung cancer, as revealed by nascent proteomic profiling

Molecular Oncology, EarlyView.
AZD9291 has shown promise in targeted cancer therapy but is limited by resistance. In this study, we employed metabolic labeling and LC–MS/MS to profile time‐resolved nascent protein perturbations, allowing dynamic tracking of drug‐responsive proteins. We demonstrated that increased NNMT expression is associated with drug resistance, highlighting NNMT ...
Zhanwu Hou, Zhen Wang, Fei Yang, Xiao Han, Lei Li, Huadong Liu   +5 more
wiley   +1 more source

Are hedonic hunger and health-related quality of life associated with obesity in adolescents? [PDF]

Front Nutr
Meral Koc B, Kenger EB, Arslan Yuksel E, Ozlu Karahan T.   +3 more
europepmc   +1 more source

Single‐cell transcriptomics redefines focal neuroendocrine differentiation as a distinct prostate cancer pathology

Molecular Oncology, EarlyView.
Single‐cell transcriptomics of prostate cancer patient‐derived xenografts reveals distinct features of neuroendocrine (NE) subtypes. Tumours with focal NE differentiation (NED) share transcriptional programmes with adenocarcinoma, differing from large and small cell neuroendocrine prostate cancer (NEPC). Our work defines the molecular landscape of NEPC,
Rosalia Quezada Urban, Shivakumar Keerthikumar, Ashlee Clark, Hong Wang, Belinda Phipson, Andrew Bakshi, Andrew Ryan, Heather Thorne, Renea A. Taylor, Mitchell G. Lawrence, Gail P. Risbridger, Roxanne Toivanen, David L. Goode   +12 more
wiley   +1 more source

Characterizing the salivary RNA landscape to identify potential diagnostic, prognostic, and follow‐up biomarkers for breast cancer

Molecular Oncology, EarlyView.
This study explores salivary RNA for breast cancer (BC) diagnosis, prognosis, and follow‐up. High‐throughput RNA sequencing identified distinct salivary RNA signatures, including novel transcripts, that differentiate BC from healthy controls, characterize histological and molecular subtypes, and indicate lymph node involvement.
Nicholas Rajan, Irina Primac, Emre Etlioglu, Laurens Debruyne, Ann Janssen, Magy Sallam, Kevin Tabury, Roel Quintens, Wiebren Tjalma, Mohammed Abderrafi Benotmane   +9 more
wiley   +1 more source

Associations between physical activity and health-related quality of life among university students in Zhuhai, China. [PDF]

Sci Rep
Tao X, Wu X, Fu J, Xiao Y, Zhong T.
europepmc   +1 more source

Microglia limit brain tumor development by restricting tumor cell proliferation and inducing T‐cell immunity

Molecular Oncology, EarlyView.
Microglia (BV2) and IL‐4‐treated BMDMs promote astrocytoma clustering and inhibit tumor growth, not shown in other macrophage cells. In vivo, microglial co‐implantation enhances CD8+ T cell infiltration, elevates Granzyme B, lowers circulating MDSCs, and extends survival only in immune‐competent mice, but not in immune‐deficient mice.
Tzu‐Chieh Sun, Ching‐Fang Yu, Sheng‐Yan Wu, Wei‐Chung Cheng, Chi‐Shiun Chiang, Fang‐Hsin Chen   +5 more
wiley   +1 more source

Impact of Orthodontic Aligner Treatment on Oral Health-Related Quality of Life.

J Pharm Bioallied Sci
Dash KS, DCosta O, Dhopte A, Kumari S, Dave M, Bagde H, Ghadage M, Patil D, Makkad RS.   +8 more
europepmc   +1 more source

Quantifying cost and health-related quality of life outcomes in different multimorbidity trajectories: a systematic review protocol. [PDF]

BMJ Open
Corcoran N, Wilson N, Mackinnon S, Blake A, Newport H, Lawless R, Jani B, Mair F, Taylor R, McIntosh E.   +9 more
europepmc   +1 more source