Results 301 to 310 of about 4,421,151 (391)

The influence of ROS1 fusion partners and resistance mechanisms in ROS1‐TKI‐treated non‐small cell lung cancer patients

Molecular Oncology, EarlyView.
This real‐world study of ROS1+ NSCLC highlights fusion diversity, treatment outcomes with crizotinib and lorlatinib, and in vitro experiments with resistance mechanisms. G2032R drives strong resistance to ROS1‐targeted TKIs, especially lorlatinib. Fusion partner location does not affect overall survival to crizotinib or lorlatinib. Findings support the
Fenneke Zwierenga, Christa Dijkhuizen, Patrick Korthuis, Wim Timens, Harry Groen, Jeroen Hiltermann, Anke van den Berg, Lyndsay Drayer, Anthonie van der Wekken   +8 more
wiley   +1 more source

PMW2: DOES TESTOSTERONE AFFECT HEALTH-RELATED QUALITY OF LIFE IN HEALTHY, ELDERLY MALES?—A PILOT STUDY

, 2000
Prasuna Reddy, CM White, AB Dunn, N.M. Moyna, Thompson Pd   +4 more
openalex   +1 more source

YAP1::TFE3 mediates endothelial‐to‐mesenchymal plasticity in epithelioid hemangioendothelioma

Molecular Oncology, EarlyView.
The YAP1::TFE3 fusion protein drives endothelial‐to‐mesenchymal transition (EndMT) plasticity, resulting in the loss of endothelial characteristics and gain of mesenchymal‐like properties, including resistance to anoikis, increased migratory capacity, and loss of contact growth inhibition in endothelial cells.
Ant Murphy, Samuel Hartzler, Paula A. Vargas Carranza, Shyaman Jayasundara, Madison E. Yates, Nimod D. Janson, Bozhi Liu, Annaleigh Benton, Majid Kazemian, Jason A. Hanna   +9 more
wiley   +1 more source

Related Factors of Health-Related Quality of Life in Female Nurses with In-Service Training Program

Florence Nightingale Journal of Nursing
Huan-Fang Lee, Hsuan-Man Hung, Hui-Ling Wang   +2 more
doaj   +1 more source

Health-related quality of life of patients with multiple sclerosis in China: a national online survey. [PDF]

Health Qual Life Outcomes
Song X, Qiao X, Jia Y, Li H, Wang P, Hu M.   +5 more
europepmc   +1 more source

PCD22: THE EFFECT OF NATIONALITY ON HEALTH-RELATED QUALITY OF LIFE IN THE GUSTO-I ANGIOGRAPHIC TRIAL

, 2000
KS Coyne, Micki Hill, Jaimi Louise Allen, M Kim, Nuria Alina Chandra, Alastair Ross   +5 more
openalex   +1 more source

Gut microbiota diversity is prognostic in metastatic hormone receptor‐positive breast cancer patients receiving chemotherapy and immunotherapy

Molecular Oncology, EarlyView.
In this exploratory study, we investigated the relationship between the gut microbiota and outcome in patients with metastatic hormone receptor‐positive breast cancer, treated in a randomized clinical trial with chemotherapy alone or chemotherapy in combination with immune checkpoint blockade.
Andreas Ullern, Kristian Holm, Nikolai Kragøe Andresen, Andreas Hagen Røssevold, Corinna Bang, Bjørn Naume, Johannes R. Hov, Jon Amund Kyte   +7 more
wiley   +1 more source

The cost and health-related quality of life of stroke management and care of acutely hospitalized cases in Mozambique. [PDF]

PLoS One
Dobe IS, Afoakwah C, Canana N, Stewart S, Mocumbi A.   +4 more
europepmc   +1 more source

Bioengineering facets of the tumor microenvironment in 3D tumor models: insights into cellular, biophysical and biochemical interactions

FEBS Open Bio, EarlyView.
The tumor microenvironment is a dynamic, multifaceted complex system of interdependent cellular, biochemical, and biophysical components. Three‐dimensional in vitro models of the tumor microenvironment enable a better understanding of these interactions and their impact on cancer progression and therapeutic resistance.
Salma T. Rafik, Deniz Bakkalci, Alexander J. MacRobert, Umber Cheema   +3 more
wiley   +1 more source