Results 191 to 200 of about 8,871,153 (259)

ABL kinase‐dependent phosphorylation of SH proteins promotes their direct interaction with CRK family SH2 domains

FEBS Letters, EarlyView.
CT10 regulator of kinase (CRK) and CRK‐Like (CRKL) are signaling adaptors driving cell adhesion, motility, differentiation, and proliferation. SH2‐domain containing (SH) proteins are enriched in YXXP motifs which when phosphorylated create preferred binding sites for CRK family SH2 domains.
Phoebe M. Cousens, Brendan W. Chandler, Anna M. Schmoker, Jaye L. Weinert, Charlotte A. Kearns, Warren T. Yacawych, Amila Šemić, Alicia M. Ebert, Bryan A. Ballif   +8 more
wiley   +1 more source

Reconstructing enzyme evolution by protein engineering

FEBS Letters, EarlyView.
Natural enzyme evolution can be retraced by protein engineering methods such as directed evolution, rational design, and ancestral sequence reconstruction. These approaches reveal how enzymes emerged from ligand‐binding scaffolds, developed varying substrate preferences, formed oligomeric complexes, adapted to environmental changes, and evolved novel ...
Lukas Drexler, Markus R. Busch, Reinhard Sterner   +2 more
wiley   +1 more source

Masculine Norm Adherence Among Australian Men: Latent Structure of the CMNI-22 and Its Links With Mental Health Outcomes. [PDF]

Health Promot J Austr
Mancini VO, Brett J, Chhabra J, Clarke J, Nevill TP, Preece DA, Seidler Z, Roberts B, Martin S.   +8 more
europepmc   +1 more source

"Highly committed but overwhelmed by constraints": a qualitative study of officials' and health staff's perspectives on the prison mental health system in Cambodia. [PDF]

BMC Public Health
Pat P, Edin K, Jegannathan B, Sebastian MS, Richter Sundberg L.   +4 more
europepmc   +1 more source

A systems approach to understanding injury care in LMICs using causal loop diagrams. [PDF]

BMJ Glob Health
Davies JI, Chu K, D'Ambruoso L, Bojke L, English R, Geduld H, Lahri S, Mahomed H, Matzopoulos R, Tako AA.   +9 more
europepmc   +1 more source

Digital CBT reduces mental disorders and boosts access to care in college students. [PDF]

Nat Hum Behav
europepmc   +1 more source

Exploring potential factors influencing perinatal mental health in Kajiado County, Kenya: a qualitative study with mothers and healthcare workers. [PDF]

BMC Public Health
Kamau C, Gabrielsson S, Makokha FW, Ntinina T, Karimi J, Munteiyan L, Ekman K, Öhlund L, Werneke U.   +8 more
europepmc   +1 more source

What is herd health management? A narrative review. [PDF]

Acta Vet Scand
Eriksen EØ, Pedersen KS, Nielsen JP.
europepmc   +1 more source