Results 221 to 230 of about 29,459,690 (400)

Uvodnik: deset let po alma-ati

open access: yesObzornik zdravstvene nege, 1988
World Health
doaj  

The Lancet Commission on pollution and health

open access: yesThe Lancet, 2017
P. Landrigan   +46 more
semanticscholar   +1 more source

Loss of proton‐sensing GPR4 reduces tumor progression in mouse models of colon cancer

open access: yesMolecular Oncology, EarlyView.
G protein‐coupled receptor 4 (GPR4) is a pH‐sensing receptor activated by acidic pH. GPR4 expression is increased in patients with inflammatory bowel disease who are at high risk of developing colorectal cancer. In mouse models, loss of GPR4 attenuated tumor progression. This correlated with increased IL2 and natural killer cell activity.
Leonie Perren   +16 more
wiley   +1 more source

Steps for Planning Health Program Evaluations: From Program Logic to Data Collection and Reporting Plans. [PDF]

open access: yesAust J Rural Health
Thomas M   +10 more
europepmc   +1 more source

The effect of multiple adverse childhood experiences on health: a systematic review and meta-analysis.

open access: yesLancet Public Health, 2017
K. Hughes   +7 more
semanticscholar   +1 more source

TRPM8 levels determine tumor vulnerability to channel agonists

open access: yesMolecular Oncology, EarlyView.
TRPM8 is a Ca2+ permissive channel. Regardless of the amount of its transcript, high levels of TRPM8 protein mark different tumors, including prostate, breast, colorectal, and lung carcinomas. Targeting TRPM8 with channel agonists stimulates inward calcium currents followed by emptying of cytosolic Ca2+ stores in cancer cells.
Alessandro Alaimo   +18 more
wiley   +1 more source

Correction to: Evidence-based Prostate Cancer Screening Interventions for Black Men: A Systematic Review. [PDF]

open access: yesJ Racial Ethn Health Disparities
Lopez A   +6 more
europepmc   +1 more source

The anticancer effect of the HDAC inhibitor belinostat is enhanced by inhibitors of Bcl‐xL or Mcl‐1 in ovarian cancer

open access: yesMolecular Oncology, EarlyView.
The pan‐HDAC inhibitor belinostat increases the expression of the pro‐apoptotic proteins Bim, Puma, and Noxa and induces apoptosis in ovarian cancer cell lines and patient‐derived tumor organoids when used at high concentrations. Moreover, inhibiting the anti‐apoptotic proteins Bcl‐xL or Mcl‐1 sensitizes these preclinical models to the cytotoxic effect
Cécilia Thomine   +10 more
wiley   +1 more source

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