Results 311 to 320 of about 27,857,248 (401)
Unignorable burden of mental health disorders among adolescents in sub-Saharan Africa: a call for urgent action. [PDF]
Gosse RA +4 more
europepmc +1 more source
Health Museums and Health Education
openaire +3 more sources
Interpreting the effects of DNA polymerase variants at the structural level
Using MAVISp and molecular dynamics simulations, we analyzed over 60 000 missense variants in POLE and POLD1 from ClinVar, COSMIC, cBioPortal, and saturation mutagenesis. Identified mechanistic indicators, including stability, binding, and long‐range, enable structural interpretation, providing ACMG‐like evidence for possible reclassification of VUS ...
Matteo Arnaudi +7 more
wiley +1 more source
Ixazomib inhibits proteasome‐mediated degradation of topoisomerase I induced by irinotecan, thereby restoring drug sensitivity and promoting tumor cell death in colorectal cancer. Irinotecan, a topoisomerase I (topoI) inhibitor, is widely used for colorectal cancer, but resistance remains a major clinical challenge.
Yuho Ebata +10 more
wiley +1 more source
The Value and Challenges of Stakeholder Engagement in Rehabilitation Learning Health Systems: A Qualitative Pilot Study of Rehabilitation Directors. [PDF]
Stetten NE +3 more
europepmc +1 more source
Health issues and needs among adolescents in Ethiopia: A cross-sectional study. [PDF]
Asari AA, Godesso A, Birhanu Z.
europepmc +1 more source
Evaluation of a Digital Intervention to Improve the Health Outcomes of Older Adults: Secondary Data Analysis. [PDF]
Chew J, Bartlett G, Hopkins L, Frings D.
europepmc +1 more source
Influence of Digital Literacy on Digital Health Usage Intention Among Patients With Cancer and Healthcare Providers. [PDF]
Kim HR +11 more
europepmc +1 more source

