Results 61 to 70 of about 22,531 (310)

Sirolimus for Extracranial Arteriovenous Malformations: A Scoping Review of the Evidence in Syndromic and Non‐Syndromic Cases

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Arteriovenous malformations (AVMs) are rare, high‐flow, vascular anomalies that can occur either sporadically or as part of a genetic syndrome. AVMs can progress with serious morbidity and even mortality if left unchecked. Sirolimus is an mTOR inhibitor that is effective in low‐flow vascular malformations; however, its role in AVMs is unclear.
Will Swansson, Ingrid Winship, Gary Hammerschlag, Laura Scardamaglia   +3 more
wiley   +1 more source

Cancer diagnosis after emergency presentation: impact of demographics, cancer types, and pandemic

Academia Oncology
Importance: Cancer diagnosis following an emergency department presentation (unscheduled care) is associated with lower cancer survival and poor patient-reported outcomes.
Filip Sosenko, Frances S. Mair, Barbara I. Nicholl, Peter Hanlon, Jim Lewsey, Michael Fleming, Daniel Mackay, Ruth Dundas, Clea Du Toit, Jocelyn Friday, Alan Stevenson, Claudia Geue, Denise Brown, Claire Hastie, Tran Q.B. Tran, Frederick K. Ho, Jill Pell, Sandosh Padmanabhan, Bhautesh Dinesh Jani   +18 more
doaj   +1 more source

Evaluating the Utility of Paired Tumor and Germline Targeted DNA Sequencing for Pediatric Oncology Patients: A Single Institution Report

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Objective To evaluate the diagnostic yield and utility of universal paired tumor–normal multigene panel sequencing in newly diagnosed pediatric solid and central nervous system (CNS) tumor patients and to compare the detection of germline pathogenic/likely pathogenic variants (PV/LPVs) against established clinical referral criteria for cancer ...
Natalie Waligorski, Rebecca Ronsley, Shannon M. Stasi, Jeffrey Stevens, Erin R. Rudzinski, Christina M. Lockwood, Sarah E. S. Leary, Bonnie L. Cole, Michelle A. Ting, Vera Paulson   +9 more
wiley   +1 more source

Bullying at work: Cognitive appraisal of negative acts, coping, wellbeing, and performance. [PDF]

, 2016
The negative outcomes of experiencing workplace bullying are well documented, but a strong theoretical explanation for this has been relatively neglected.
Hewett, Rebecca, Liefooghe, Andreas, Roongrerngsuke, Siriyupa, Visockaite, Gintare   +3 more
core   +3 more sources

Preferences of Pediatric Patients and Their Caregivers for Chemotherapy‐Induced Nausea and Vomiting Control Endpoints: A Mixed Methods Study

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Purpose Although not always achieved, complete chemotherapy‐induced nausea and vomiting (CINV) control is the conventional goal of CINV prophylaxis. In this two‐center, mixed‐methods study, we sought to understand the preferences of adolescent patients and family caregivers for CINV control endpoints.
Haley Newman, Tadi Hondonga, Alison Berry, Caitlin Elgarten, Jason Freedman, Katelyn Oranges, Sara McDonough, Caroline Diorio, L. Lee Dupuis   +8 more
wiley   +1 more source

Sustainability in food-based dietary guidelines: a review of recommendations around meat and dairy consumption and their visual representation

Annals of Medicine
Background The transition away from high meat and dairy consumption and towards more plant-based diets is vital for environmental sustainability targets, including reducing greenhouse gas (GHG) emissions and land use associated with food.
Maddie Sinclair, Emilie Combet, Tess Davis, Esther K. Papies   +3 more
doaj   +1 more source

Do airborne biogenic chemicals interact with the PI3K/Akt/mTOR cell signalling pathway to benefit human health and wellbeing in rural and coastal environments? [PDF]

, 2015
Living and taking recreation in rural and coastal environments promote health and wellbeing, although the causal factors involved are unclear. It has been proposed that such environments provide a counter to the stresses of everyday living, leading to ...
Moore, MN
core   +1 more source

Intravitreal GD2‐Specific Chimeric Antigen Receptor T‐Cell Therapy for Refractory Retinoblastoma

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Effective treatments for advanced, treatment‐resistant retinoblastoma (RB) remain limited. GD2‐specific chimeric antigen receptor (CAR) T cells show potent antitumor activity with minimal toxicity but have not previously been evaluated in RB.
Subongkoch Subhadhirasakul, Jatuporn Sujjitjoon, Pa‐thai Yenchitsomanus, Kridtin Jarutatsanangkoon, Ng Wei Loon, Kleebsabai Sanpakit, Jassada Buaboonnam, Chayamon Takpradit, Pornpimon Yuti, Nunghathai Sawasdee, Piriya Luangwattananun, Siripakorn Sangkitporn, Arnan Limmahachai, La‐ongsri Atchaneeyasakul   +13 more
wiley   +1 more source

Pre-existing depression, anxiety and trauma as risk factors for the development of post-traumatic stress disorder symptoms following wildfires

Psychiatry Research Communications
The trauma of wildfires leads to one of the most challenging and treatment resistant mental health conditions-namely-post-traumatic stress disorder (PTSD).
Fadia Isaac, Samia R. Toukhsati, Britt Klein, Mirella Di Benedetto, Gerard A. Kennedy   +4 more
doaj   +1 more source

Breastfeeding as a Mechanism to Reduce Postpartum Depression with Weight as a Major Contributing Factor in Hispanic Women [PDF]

, 2018
Postpartum Depression (PPD) is the most common childbearing-related illness around the globe affecting both mothers and their children; yet minimal longitudinal research has been done to study the effect of depressive symptomatology on breastfeeding ...
Wilson, Celia
core   +1 more source