Results 181 to 190 of about 1,602,703 (297)

Development and validation of a case identification algorithm for hand trauma patients using health administrative data and the epidemiology of hand trauma in a universal healthcare system. [PDF]

BMJ Open
Wong CR, Tu K, Hernandez A, Urbach DR, Witiw C, Hansen B, Ko A, Tsai P, Baltzer H.   +8 more
europepmc   +1 more source

Association between opioid prescription profiles and adverse health outcomes in opioid users referred for sleep disorder assessment: a secondary analysis of health administrative data. [PDF]

Front Sleep, 2023
Kendzerska T, Malhotra A, Gershon AS, Povitz M, McIsaac DI, Aaron SD, Bryson GL, Talarico R, Godbout M, Tanuseputro P, Chung F.   +10 more
europepmc   +1 more source

Peroxidasin enables melanoma immune escape by inhibiting natural killer cell cytotoxicity

Molecular Oncology, EarlyView.
Peroxidasin (PXDN) is secreted by melanoma cells and binds the NK cell receptor NKG2D, thereby suppressing NK cell activation and cytotoxicity. PXDN depletion restores NKG2D signaling and enables effective NK cell–mediated melanoma killing. These findings identify PXDN as a previously unrecognized immune evasion factor and a potential target to improve
Hsu‐Min Sung, David Bickel, Lena C. M. Krause, Daria Ezeriņa, Christian Ickes, Julian Wojtachnia, Christine S. Gibhardt, Magdalena Shumanska, Khadija Wahni, Andrea Paluschkiwitz, Julia Malo Pueyo, Ekaterina Baranova, Wim Vranken, Hedwig Stanisz, Ioana Stejerean‐Todoran, Michael P. Schön, Joris Messens, Ivan Bogeski   +17 more
wiley   +1 more source

Strategies for population-level identification of post-acute sequelae of COVID-19 through health administrative data. [PDF]

Front Public Health
Mazzali C, Magnoni P, Zucchi A, Maifredi G, Cavalieri d'Oro L, Gambino ML, Fanetti AC, Perotti PG, Villa M, Valsecchi MG, Vigani D, Lucifora C, Russo AG.   +12 more
europepmc   +1 more source

An examination of the association between marital status and prenatal mental disorders using linked health administrative data. [PDF]

BMC Pregnancy Childbirth, 2022
Bedaso A, Adams J, Peng W, Xu F, Sibbritt D.   +4 more
europepmc   +1 more source

Phenotypic and genotypic characterization of single circulating tumor cells in the follow‐up of high‐grade serous ovarian cancer

Molecular Oncology, EarlyView.
Single circulating tumor cells (sCTCs) from high‐grade serous ovarian cancer patients were enriched, imaged, and genomically profiled using WGA and NGS at different time points during treatment. sCTCs revealed enrichment of alterations in Chromosomes 2, 7, and 12 as well as persistent or emerging oncogenic CNAs, supporting sCTC identity.
Carolin Salmon, Rui P. L. Neves, Nikolas H. Stoecklein, Sven‐Thorsten Liffers, Jens Siveke, Jan D. Kuhlmann, Pauline Wimberger, Paul Buderath, Rainer Kimmig, Sabine Kasimir‐Bauer   +9 more
wiley   +1 more source

Measuring geographic proximity and continuity with family medicine at end-of-life: Protocol for a population-level retrospective cohort study using Canadian Health Administrative Data. [PDF]

PLoS One
Hafid S, Mbuagbaw L, Newbold B, Costa A, Gayowsky A, Gozdyra P, Jones A, Isenberg S, Gallagher E, Howard M.   +9 more
europepmc   +1 more source

An Elastic Net Regression Model for Identifying Long COVID Patients Using Health Administrative Data: A Population-Based Study. [PDF]

Open Forum Infect Dis, 2022
Binka M, Klaver B, Cua G, Wong AW, Fibke C, Velásquez García HA, Adu P, Levin A, Mishra S, Sander B, Sbihi H, Janjua NZ.   +11 more
europepmc   +1 more source

Combining antibody conjugates with cytotoxic and immune‐stimulating payloads maximizes anti‐cancer activity

Molecular Oncology, EarlyView.
Methods to improve antibody–drug conjugate (ADC) treatment durability in cancer therapy are needed. We utilized ADCs and immune‐stimulating antibody conjugates (ISACs), which are made from two non‐competitive antibodies, to enhance the entry of toxic payloads into cancer cells and deliver immunostimulatory agents into immune cells.
Tiexin Wang, Dong Jun Koo, Peter M. Tessier, Greg M. Thurber   +3 more
wiley   +1 more source

Identifying opioid agonist treatment prescriber networks from health administrative data: A validation study. [PDF]

PLoS One
Kurz M, Tatangelo M, Morin KA, Zanette M, Krebs E, Marsh DC, Nosyk B.   +6 more
europepmc   +1 more source