Results 131 to 140 of about 164,122 (292)

The Health and Demographic Surveillance System (HDSS) in Nouna, Burkina Faso, 1993–2007

open access: yesGlobal Health Action, 2010
The Nouna1 Health and Demographic Surveillance System (HDSS) is located in rural Burkina Faso and has existed since 1992. Currently, it has about 78,000 inhabitants.
Ali Sié   +9 more
doaj   +1 more source

Anaemia in Pregnancy and Infant Mortality in Tanzania. [PDF]

open access: yes, 2004
Tanzania is an area of moderate to high risk for severe anaemia during pregnancy. There is extensive literature examining the consequences of severe anaemia for pregnant women, but the impact this problem has on their infants in malaria-endemic regions ...
Mukasa, Oscar   +13 more
core   +1 more source

Polystyrene Nanoplastics Drive β‐Cell Dedifferentiation Through Dendritic Cell‐Intrinsic MHC‐I‐Dependent Inflammatory Crosstalk

open access: yesAdvanced Science, EarlyView.
Polystyrene nanoplastics disrupt pancreatic immune–endocrine homeostasis by promoting MHC‐I‐associated dendritic cell activation and inflammatory crosstalk with β cells. This immune remodeling drives β‐cell dedifferentiation, impairs insulin secretion, and aggravates metabolic dysfunction, revealing a previously unrecognized immunometabolic mechanism ...
Conghui Qiao   +10 more
wiley   +1 more source

Evaluation of a village-informant driven demographic surveillance system in Karonga, Northern Malawi [PDF]

open access: yes
This paper describes and evaluates the first demographic surveillance system (DSS) in Malawi, covering a rural population of 30,000. Unlike others, the Karonga DSS relies on trained village informants using formatted registers for the primary ...
Paul EM Fine   +9 more
core  

Tumor Exposomics: A New Paradigm for Individualized Continuous Exposure Monitoring

open access: yesAdvanced Science, EarlyView.
Tumor exposomics integrates continuous monitoring of environmental exposures, endogenous biological responses, and behavioral factors within a unified temporal framework. By combining multimodal sensing technologies with AI‐enabled causal modeling, this emerging paradigm reconstructs exposure‐damage trajectories and supports individualized dynamic risk
Kaicheng Shen   +6 more
wiley   +1 more source

Single‐Cell Profiling Reveals Clonally Expanded CX3CR1+ T Cells in Anti‐NMDA Receptor Encephalitis

open access: yesAdvanced Science, EarlyView.
CX3CR1+ T cells are associated with peripheral and central immune alterations in anti‐NMDA receptor encephalitis (NMDAR‐E). They show potential responsiveness to GluN1 (NR1) peptides, potential interactions with peripheral B cells, clonal expansion, increased CD137/CD154 expression, and inflammatory cytokine production. Their preferential cerebrospinal
Lin Yan   +13 more
wiley   +1 more source

Age at First Marriage and Fertility Decline in Dabat Health and Demographic Surveillance System Site, Northwest Ethiopia: Decomposition Analysis

open access: yesInternational Journal of Women's Health, 2021
Nega Alazbih,1 Assefa Hailemariam Kaya,2 Mezgebu Mengistu,3 Kassahun Gelaye4 1Department of Population Studies, University of Gondar, Gondar, Ethiopia; 2Population Studies, Addis Ababa University, Addis Ababa, Ethiopia; 3Department of Health System and ...
Alazbih N, Kaya AH, Mengistu M, Gelaye K
doaj  

Self-reported health and health care use in an ageing population in the Agincourt sub-district of rural South Africa [PDF]

open access: yes, 2013
Background: South Africa is experiencing a demographic and epidemiological transition with an increase in population aged 50 years and older and rising prevalence of non-communicable diseases. This, coupled with high HIV and tuberculosis prevalence, puts
Kathleen Kahn   +13 more
core   +1 more source

Metabolic Signatures for Liver Cancer Diagnosis and Mechanistic Insights: A Large‐Scale, Multicenter Study

open access: yesAdvanced Science, EarlyView.
A large‐scale multicenter serum metabolomics study (13 centers, n = 2,149) identified a 9‐metabolite + AFP diagnostic signature for liver cancer (AUC = 0.93). Among the signature, nicotinamide (NAM) was validated as an oncometabolite: NAM enhances NAD+ synthesis, activating SIRT1 to deacetylate and stabilize HIF1α, thereby driving glycolysis, MAPK ...
Yongjie Xu   +13 more
wiley   +1 more source

Splenic Tropism and Spleen‐Modulated Systemic Inflammation in Acute Plasmodium vivax Malaria

open access: yesAmerican Journal of Hematology, EarlyView.
ABSTRACT In chronic Plasmodium vivax (Pv) infection, the spleen accounts for over 98% of total‐body parasite biomass. Whether splenic tropism also occurs in acute infection and how the spleen influences pathogenesis have not been systematically explored. In Papua, Indonesia, we compared clinical and hematology data in 24 spleen‐intact and 25 previously
Steven Kho   +27 more
wiley   +1 more source

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