Results 241 to 250 of about 164,122 (292)

From Surgical Innovation to Population Impact: Robot‐Assisted Radical Prostatectomy and the Evolution of Surgical Public Health in Brazil's Unified Health System

Chronic Diseases and Translational Medicine, EarlyView.
ABSTRACT Brazil's Unified Health System (Sistema Único de Saúde, SUS) represents one of the world's largest universal health systems and provides a unique real‐world platform for integrating prevention, diagnosis, treatment, and survivorship across the cancer continuum.
Leonardo Oliveira Reis
wiley   +1 more source

Population Nutritional Status in Addis Health and Demographic Surveillance System (ADDIS-HDSS), Addis Ababa, Ethiopia. [PDF]

Ethiop J Health Sci
Shifraw T, Abdelmenan S, Berhane HY, Gulema H, Beyan S, Workneh F, Yibeltal K, Tsegaye S, Bekele G, Fasil N, Wang D, Partap U, Sudfeld CR, Fawzi W, Demissie M, Worku A, Berhane Y.   +16 more
europepmc   +1 more source

A Practical Guide to Implementing Real‐World Evidence as Primary Basis for Approval and Label Expansion

Clinical Pharmacology &Therapeutics, EarlyView.
In June 2026, the FDA issued a revised draft guidance describing the circumstances in which one adequate and well‐controlled clinical investigation plus confirmatory evidence may satisfy the statutory substantial evidence standard for establishing efficacy and safety. Confirmatory evidence includes real‐world evidence (RWE).
Tracy J. Mayne, Maurice A. Brookhart, Nancy A. Dreyer   +2 more
wiley   +1 more source

Urogenital Infection Risk Associated With SGLT2 Inhibitors Versus DPP‐4 Inhibitors in Type 2 Diabetes and Chronic Kidney Disease: A Nationwide Target Trial Emulation

Clinical Pharmacology &Therapeutics, EarlyView.
Although sodium‐glucose cotransporter‐2 inhibitors (SGLT2i) are recommended for patients with type 2 diabetes mellitus (T2DM) and chronic kidney disease (CKD), concerns regarding urogenital infections persist. Therefore, we evaluated the risk of urinary tract infection (UTI) and genital tract infection (GTI) after SGLT2i initiation in this population ...
Young‐Mi Ah, Junsung Nam, Jung Wook Youn, Yun Mi Yu, Soyoung Kang   +4 more
wiley   +1 more source

Household Sanitation and Crowding Status in Addis Health and Demographic Surveillance System (Addis-HDSS) in Addis Ababa, Ethiopia. [PDF]

Ethiop J Health Sci
Yallew WW, Fasil N, Abdelmenan S, Berhane HY, Tsegaye S, Wang D, Fawzi W, Demissie M, Worku A, Birhane Y.   +9 more
europepmc   +1 more source

High‐Dimensional Spectral Flow Cytometry Panel for Immunophenotypic Characterization of Fixed Whole Blood Samples

Cytometry Part A, EarlyView.
ABSTRACT Peripheral blood mononuclear cells (PBMCs) are commonly used for immune profiling in clinical research, but their isolation and cryopreservation present logistical challenges, particularly in settings with limited access to research facilities. To address this, we implemented a whole blood fixation protocol to preserve surface protein epitopes
Vaishnavi Parthasarathy, Alexander T. Heubeck, Tyanna Stuckey, Veronica Hernandez, Blessing Musgrove, Maia M. Bennett‐Boehm, Troy Torgerson, Peter Skene, Julian Reading   +8 more
wiley   +1 more source

Mortality in children and adolescents in Western Democratic Republic of Congo: retrospective analysis of verbal autopsy and demographic data from the Kimpese Health and Demographic Surveillance System. [PDF]

BMJ Paediatr Open
Fumwakwau JK, Schedwin M, Ngale MA, Hildenwall H, Alfven T, Mapatano MA, King C, Phanzu DM.   +7 more
europepmc   +1 more source

Extended routine lymphocyte immunophenotyping refines individual immune organization across a heterogeneous patient cohort

Cytometry Part B: Clinical Cytometry, EarlyView.
Abstract Routine TBNK immunophenotyping detects the major lymphocyte compartments but may underestimate the biologically relevant variation contributed by less frequent but well‐defined minor lymphocyte subsets. This study evaluated whether extending routine TBNK immunophenotyping with minor lymphocyte subsets provides complementary, analytically ...
Carlos Agustin Villegas Valverde, Yendry Ventura Carmenate, Vianed Marsan Suarez, Yandy Marx Castillo Aleman, Imilla Casado Hernandez, Rachely Hernandez Corrales   +5 more
wiley   +1 more source

Self-rated Health Status of the Adult Population in Addis Health and Demographic Surveillance System (Addis-HDSS), Addis Ababa, Ethiopia. [PDF]

Ethiop J Health Sci
Tewahido D, Abdelmenan S, Workneh F, Tarekegn W, Yibeltal K, Sime H, Berhane HY, Tsegaye S, Fasil N, Wang D, Partap U, Fawzi W, Demissie M, Worku A, Berhane Y.   +14 more
europepmc   +1 more source

Monitoring Injected Drug Use in Greece Through Syringe Residue Analysis: A Multicity Study Within the ESCAPE Network

Drug Testing and Analysis, EarlyView.
A total of 2121 used syringes were analyzed in Athens, Thessaloniki, and Patras between 2022 and 2024. Distinct drug‐use patterns were observed across the three cities. Benzodiazepines, pregabalin, methadone, and fentanyl were increasingly detected in 2024.
Christina Matiaki, Anastasios Trakakis, Athanasios Theocharis, Chara Parpala, Chara Kotsailidou, Alexandros Psarianos, Emmanouil Chatzichristofis, Eleni Zagelidu, Panagiota Roussou, Nikolaos Raikos, Orthodoxia Mastrogianni   +10 more
wiley   +1 more source