Results 41 to 50 of about 1,003,532 (311)
Tau acetylation at K331 has limited impact on tau pathology in vivo
We mapped tau post‐translational modifications in humanized MAPT knock‐in mice and in amyloid‐bearing double knock‐in mice. Acetylation within the repeat domain, particularly around K331, showed modest increases under amyloid pathology. To test functional relevance, we generated MAPTK331Q knock‐in mice.
Shoko Hashimoto +3 more
wiley +1 more source
Health awareness among Emirati family
تهدف هذه الدراسة إلى التعرف على مستوى الوعي الصحي لدى الأسرة الإماراتية بهدف المساهمة في تحقيق الأمن الصحي الذي يشكل جزءا مهما من الأمن الشامل (الاجتماعي والاقتصادي والتعليمي والثقافي ....) من خلال التعرف على أهم المشكلات الصحية التي يعاني منها المجتمع ...
Ahmad Falah Alomosh +3 more
doaj +1 more source
Gut microbiome and aging—A dynamic interplay of microbes, metabolites, and the immune system
Age‐dependent shifts in microbial communities engender shifts in microbial metabolite profiles. These in turn drive shifts in barrier surface permeability of the gut and brain and induce immune activation. When paired with preexisting age‐related chronic inflammation this increases the risk of neuroinflammation and neurodegenerative diseases.
Aaron Mehl, Eran Blacher
wiley +1 more source
Introduction and objectives Although physical activity has been found to reduce the risk of cardiovascular diseases and depression in the general population, little is known about physical patterns and the link with postnatal depressive symptoms and ...
Dominika Szalewska +1 more
doaj +1 more source
Regarding Health Awareness Days
A letter to the editor is presented in response to the article "Health Awareness Days: Sufficient Evidence to Support the Craze?" by Jonathan Purtle and Leah A. Roman in the June 2015 issue, along with a reply from the authors.
openaire +3 more sources
Diversity and complexity in neural organoids
Neural organoid research aims to expand genetic diversity on one side and increase tissue complexity on the other. Chimeroids integrate multiple donor genomes within single organoids. Self‐organising multi‐identity organoids, exogenous cell seeding, or enforced assembly of region‐specific organoids contribute to tissue complexity.
Ilaria Chiaradia, Madeline A. Lancaster
wiley +1 more source
The human gut microbiome across the life course
Despite significant individual variation and continuous change throughout life, the human gut microbiome follows some life stage‐specific trends. This article provides a brief overview of how gut microbiome composition shifts across different phases of life. Created in BioRender. Özkurt, E. (2026) https://BioRender.com/8q4nrnc.
Alise J. Ponsero +4 more
wiley +1 more source
Background Autism spectrum condition (ASC) is a neurodevelopmental disorder characterized by persistent difficulties in social communication and repetitive behaviors.
Modia Batterjee
doaj +1 more source
IntroductionNursing leadership and the voice of nurses are crucial for developing person-centred care in hospices. Concerns have been raised that, as palliative care has evolved from its original vision and become more integrated into the mainstream ...
Erna Haraldsdottir +2 more
doaj +1 more source
Proteostasis and the gut microbiota play a key role in shaping host physiology. Microbiota‐derived metabolites, vitamins, and RNA modulate host proteostasis. Findings from model systems, including C. elegans, indicate microbes can either stabilize or disrupt host proteostasis.
Abhishek Anil Dubey, Maria Ermolaeva
wiley +1 more source

