Results 31 to 40 of about 802,069 (266)

Claudin‐6 Protein Expression in Atypical Teratoid/Rhabdoid Tumors Is Strongly Enriched in the Molecular Subgroup AT/RT‐TYR

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Claudin‐6 has emerged as a promising immunotherapeutic target, yet protein‐level data in atypical teratoid/rhabdoid tumors (AT/RTs) have been inconsistent. We analyzed 36 well‐characterized AT/RT samples and found membranous claudin‐6 protein expression in 58% of cases, with striking enrichment in the molecular subgroup AT/RT‐TYR (100%) and ...
Victoria E. Fincke, Christian Thomas, Michael C. Frühwald, Pascal D. Johann, Martin Hasselblatt   +4 more
wiley   +1 more source

Anxiety as a mediator in the relationship of perceived stress and social support with emotional eating in female university teachers

BMC Public Health
Background Emotional eating is increasingly recognized as a significant risk factor for both physical and psychological health, especially in academic settings where work-related stress and social demands are high.
Jacksaint Saintila, Luis Alberto Geraldo-Campos, Susan M. Oblitas-Guerrero, Giovanna Larraín Távara, Isabel G. Lizarraga-De-Maguiña, Elmer López-López, Yaquelin E. Calizaya-Milla   +6 more
doaj   +1 more source

Emapalumab for Immune Effector Cell‐Associated Hemophagocytic Lymphohistiocytosis‐Like Syndrome Following CD19‐Directed CAR‐T in Two Patients With B‐ALL: Clinical and Biomarker Correlates

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Immune effector cell‐associated hemophagocytic lymphohistiocytosis‐like syndrome (IEC‐HS) is a life‐threatening hyperinflammatory toxicity distinct from cytokine release syndrome (CRS) and neurotoxicity following chimeric antigen receptor T‐cell (CAR‐T) therapy. In a single‐institution retrospective cohort of pediatric and young adult patients
Thomas J. Galletta, Jeremy D. Rubinstein, Christopher E. Dandoy, Ruby Khoury, Angela Faulhaber, Christine L. Phillips, Christa Krupski   +6 more
wiley   +1 more source

Early life adversity increases striatal dopamine D1 receptor density and promotes social alcohol drinking in mice, especially males

Translational Psychiatry
The brain’s reward-processing circuitry remains sensitive to experience throughout early life and into adulthood, allowing individuals to adapt to their unique environments.
Lucy G. Anderson, Anna E. Tischer, Roland Bock, Michael Michaelides, Veronica A. Alvarez   +4 more
doaj   +1 more source

Increased Risk of Sarcomas in Children With Congenital Anomalies: Findings From the Genetic Overlap Between Anomalies and Cancer in Kids (GOBACK) Registry Linkage Study

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Background Pediatric sarcomas are a heterogeneous group of tumors that contribute disproportionately to cancer mortality in children. Although congenital anomalies are among the strongest known risk factors for childhood cancer, the risk of specific sarcoma subtypes among affected individuals has not yet been thoroughly evaluated. Procedure We
Russ Wolters, Ji Yun Tark, Tiffany M. Chambers, Tania A. Desrosiers, Michael E. Scheurer, Charles Shumate, Wendy N. Nembhard, Mahsa M. Yazdy, Eirini Nestoridi, Amanda E. Janitz, Jean Paul Tanner, Russell S. Kirby, Jason L. Salemi, Yao Yu, Chad D. Huff, Sharon E. Plon, Philip J. Lupo, Jeremy M. Schraw   +17 more
wiley   +1 more source

Preexisting risk-avoidance and enhanced alcohol relief are driven by imbalance of the striatal dopamine receptors in mice

Nature Communications
Alcohol use disorder (AUD) is frequently comorbid with anxiety disorders, yet whether alcohol abuse precedes or follows the expression of anxiety remains unclear.
Miriam E. Bocarsly, Marlisa J. Shaw, Emilya Ventriglia, Lucy G. Anderson, Hannah C. Goldbach, Catherine E. Teresi, Marilyn Bravo, Roland Bock, Patrick Hong, Han Bin Kwon, Imran M. Khawaja, Rishi Raman, Erin M. Murray, Jordi Bonaventura, Dennis A. Burke, Michael Michaelides, Veronica A. Alvarez   +16 more
doaj   +1 more source

Supporting Survivor‐Centered Care Through Digital Health Integration

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Survivors of childhood cancer face barriers to receiving guideline‐based, long‐term follow‐up care. Two digital tools, Passport for Care (PFC) and Cancer SurvivorLink (SurvivorLink), address complementary gaps by enabling tailored survivorship care plan (SCP) generation, updating, storage, and sharing.
Jordan G. Marchak, Rebecca Williamson‐Lewis, Michael O'Connor, Michael Palgon, Yu‐Ra Kim, Michael Schuckenbrock, Paula Edwards, Abraham Mendoza, Anthony Adams, Brian Arriaga‐Solis, Justin Parker, Harry Tinoco‐Giraldo, Jason King, C. Michael Fordis, Karen E. Effinger, Maria Monica Gramatges   +15 more
wiley   +1 more source

Non-linear relationships and interaction effects between different types of screen time and mental health issues among Hong Kong adolescents

Psychiatry Research Communications
Background: Non-linear relationship of different types of screen time with adolescent mental health problems remains unclear. Objective: To identify non-linear relationships of internet gaming and social media use with probable depression and suicidal ...
Qian Li, Kylie Kai-yi Chan, Miguel R. Ramos, Xin Wang, Samuel Yeung-shan Wong, Xue Yang   +5 more
doaj   +1 more source

Woman's Sexual Health Knowledge and Needs Assessment in Behavioral Clinics and Shelters in Tehran

Journal of Family and Reproductive Health, 2019
Objective: The aim of this study was to assess the sexual health knowledge among females seeking consultation in behavioral clinics or shelters with emphasis on sexual routs of HIV transmission.
Katayouon Tayeri, Zahra Bayat Jozani, Haniyeh Golchehregan, Zohreh Rostam Afshar, Lila Taj, Sara Ahsani Nasab, Maryam Foroughi, Pegah Mirzapour, Minoo Mohraz, Zohreh Mahmoodi, Zeinab Talebi, Mahbobeh Haji Abdolbaghi   +11 more
doaj   +1 more source

Efficacy and Safety Analysis of Roxarestat in Regulating Renal Anemia in Patients on Maintenance Hemodialysis

Therapeutic Apheresis and Dialysis, EarlyView.
ABSTRACT Objective To compare the efficacy and safety of roxarestat versus recombinant human erythropoietin (rhEPO) in the management of renal anemia in patients undergoing maintenance hemodialysis. Methods This was a prospective, open‐label, randomized controlled trial.
Lingling Chen, Junjie Zhu, Qiaonan Ge
wiley   +1 more source