Results 161 to 170 of about 18,630,386 (270)

A Community-Based Participatory Action Research with Women from Disadvantaged Populations: Strengths and Weaknesses of a Multiple Health Behaviour Change Intervention. [PDF]

Int J Environ Res Public Health, 2022
Sanz-Remacha M, Aibar A, Abós Á, Generelo-Lanaspa E, García-González L.   +4 more
europepmc   +1 more source

The role of miR‐335‐5p in the redifferentiation of BRAF p.V600E thyroid cancers

Molecular Oncology, EarlyView.
The BRAF p.V600E mutation promotes thyroid cancer dedifferentiation and radioiodine resistance. Using a network approach, we identified miR‐335‐5p as a key regulator of BRAF‐mutated thyroid tumors. Restoring miR‐335‐5p increased thyroid‐specific gene expression and iodine uptake in cells and organoids.
Valeria Pecce, Simone Bini, Marialuisa Sponziello, Giorgio Grani, Giulia Fiscon, Paola Paci, Lorenzo Farina, Rosa Falcone, Valentina Maggisano, Sebastiano Filetti, Cosimo Durante, Antonella Verrienti   +11 more
wiley   +1 more source

Author Correction: Effect of a digital health behaviour change support system on cardiovascular disease risk in a randomized weight loss trial. [PDF]

NPJ Digit Med
Turkkila E, Merikallio H, Savolainen MJ, Heikkilä L, Oinas-Kukkonen H, Salonurmi T, Teeriniemi AM, Jokelainen T, Hukkanen J.   +8 more
europepmc   +1 more source

Understanding public attitudes to death talk and advance care planning in Northern Ireland using health behaviour change theory: a qualitative study. [PDF]

BMC Public Health, 2022
Graham-Wisener L, Nelson A, Byrne A, Islam I, Harrison C, Geddis J, Berry E.   +6 more
europepmc   +1 more source

Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment

Molecular Oncology, EarlyView.
This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
wiley   +1 more source

Making every contact count with seldom-heard groups? A qualitative evaluation of voluntary and community sector (VCS) implementation of a public health behaviour change programme in England. [PDF]

Health Soc Care Community, 2022
Harrison D, Wilson R, Graham A, Brown K, Hesselgreaves H, Ciesielska M.   +5 more
europepmc   +1 more source

Circular RNA expression landscapes in myelodysplastic neoplasms: Associations with mutational signatures and disease progression

Molecular Oncology, EarlyView.
In this explorative study, the abundance of circular RNA molecules in bone marrow stem cells was found to be elevated in patients with high‐risk myelodysplastic neoplasms, and to be associated with an increased risk of progression to acute myeloid leukemia.
Eileen Wedge, Morten Tulstrup, Gabriele Todisco, Pedro Moura, Christophe Côme, Jakob Werner Hansen, Jakob Schmidt Jespersen, Balthasar Schlotmann, Maria Creignou, Mette Dahl, Claudia Schöllkopf, Klas Raaschou‐Jensen, Krister Wennerberg, Bo Porse, Joachim Weischenfeldt, Eva Hellström‐Lindberg, Lasse Sommer Kristensen, Kirsten Grønbæk   +17 more
wiley   +1 more source

Effect of a digital health behaviour change support system on cardiovascular disease risk in a randomized weight loss trial. [PDF]

NPJ Digit Med
Turkkila E, Merikallio H, Savolainen MJ, Heikkilä L, Oinas-Kukkonen H, Salonurmi T, Teeriniemi AM, Jokelainen T, Hukkanen J.   +8 more
europepmc   +1 more source

IMPDH inhibition enhances cytarabine efficacy in SAMHD1‐expressing leukaemia cells via guanine nucleotide depletion

Molecular Oncology, EarlyView.
Cytarabine is a key therapy for acute myeloid leukaemia (AML), but its efficacy is limited by the dNTPase SAMHD1, which hydrolyses its active metabolite. Screening nucleotide biosynthesis inhibitors revealed that IMPDH inhibitors selectively sensitise SAMHD1‐proficient AML cells to cytarabine.
Miriam Yagüe‐Capilla, Christopher Dirks, Caroline Eiden, Sonja K. Fesenmayer, Femke M. Hormann, Yolande Klootsema, Ingrid Lilienthal, Si Min Zhang, Nikolas Herold, Sean G. Rudd   +9 more
wiley   +1 more source

The approaches, theories, models, frameworks, and methods in designing toolkits to support healthcare providers in health behaviour change: A scoping review protocol. [PDF]

PLoS One
Scandiffio J, Sureshkumar A, Feng G, Gaid D, Wasilewski M, Woods N, Donkers S, Simpson R, Munce S.   +8 more
europepmc   +1 more source