Results 81 to 90 of about 18,630,386 (270)

An ontological framework for organising and describing behaviours: The Human Behaviour Ontology [version 2; peer review: 1 approved, 2 approved with reservations]

Wellcome Open Research
Background Human behaviours have been classified in domains such as health, occupation and sustainability. We aimed to develop a broadly applicable behavioural framework to facilitate integrating evidence across domains.
Alison J. Wright, Robert West, Janna Hastings, Lisa Zhang, Oscar Castro, Marta M. Marques, Emily Hayes, Elizabeth Corker, Micaela Santilli, Susan Michie, Marie Johnston, Gabriella Stuart, Paulina M. Schenk   +12 more
doaj   +1 more source

Gut microbiome and aging—A dynamic interplay of microbes, metabolites, and the immune system

FEBS Letters, EarlyView.
Age‐dependent shifts in microbial communities engender shifts in microbial metabolite profiles. These in turn drive shifts in barrier surface permeability of the gut and brain and induce immune activation. When paired with preexisting age‐related chronic inflammation this increases the risk of neuroinflammation and neurodegenerative diseases.
Aaron Mehl, Eran Blacher
wiley   +1 more source

A review of health behaviour theories: how useful are these for developing interventions to promote long-term medication adherence for TB and HIV/AIDS? [PDF]

, 2007
BACKGROUND: Suboptimal treatment adherence remains a barrier to the control of many infectious diseases, including tuberculosis and HIV/AIDS, which contribute significantly to the global disease burden. However, few of the many interventions developed to
Munro Salla, Jimmy Volmink, Lewin, Simon, Volmink, Jimmy, Simon Lewin, Lewin Simon, Swart, Tanya, Swart Tanya, Munro, Salla A., Salla Munro, Munro, Salla, Lewin, Simon A., Tanya Swart, Volmink Jimmy   +13 more
core   +2 more sources

An ontology of mechanisms of action in behaviour change interventions [version 2; peer review: 2 approved]

Wellcome Open Research
Background Behaviour change interventions influence behaviour through causal processes called “mechanisms of action” (MoAs). Reports of such interventions and their evaluations often use inconsistent or ambiguous terminology, creating problems for ...
Candice Moore, Alison J. Wright, Verena Schneider, Robert West, Emily Hayes, Janna Hastings, Ella Howes, Susan Michie, Fabiana Lorencatto, Paulina M. Schenk   +9 more
doaj   +1 more source

The Human Behaviour-Change Project: harnessing the power of artificial intelligence and machine learning for evidence synthesis and interpretation

Implementation Science, 2017
Background Behaviour change is key to addressing both the challenges facing human health and wellbeing and to promoting the uptake of research findings in health policy and practice.
Susan Michie, James Thomas, Marie Johnston, Pol Mac Aonghusa, John Shawe-Taylor, Michael P. Kelly, Léa A. Deleris, Ailbhe N. Finnerty, Marta M. Marques, Emma Norris, Alison O’Mara-Eves, Robert West   +11 more
doaj   +1 more source

Health teaching and behavioural change [PDF]

, 2019
Abstract This chapter discusses health information and raising health awareness. It explains how these feed into behavioural change, both in individuals and in communities, as a key to improving health. It describes ways in which behavioural change can be brought about, starting with transformation in our own attitudes.
openaire   +1 more source

Valosin‐containing protein counteracts ATP‐driven dissolution of FUS condensates through its ATPase activity in vitro

FEBS Letters, EarlyView.
Biomolecular condensates formed by fused in sarcoma (FUS) are dissolved by high ATP concentrations yet persist in cells. Using a reconstituted system, we demonstrate that valosin‐containing protein (VCP), an AAA+ ATPase, counteracts ATP‐driven dissolution of FUS condensates through its D2 ATPase activity.
Hitomi Kimura, Shin‐ichi Tate, Kyota Yasuda   +2 more
wiley   +1 more source

Theoretical explanations for maintenance of behaviour change: a systematic review of behaviour theories [PDF]

, 2016
Background: Behaviour change interventions are effective in supporting individuals in achieving temporary behaviour change. Behaviour change maintenance, however, is rarely attained.
Kwasnicka, Dominika, Dombrowski, S., Dombrowski, Stephan U, Sniehotta, Falko F, Sniehotta, F., White, Martin, White, M.   +6 more
core   +1 more source

An evaluation of Scottish green health prescriptions using the APEASE criteria

BMC Primary Care
Background Time spent in green space such as parks and forests can have positive effects on physical and mental health. Green Health Partnerships were set up in Scotland to promote use of green space for health improvement.
Neil Howlett, Imogen Freethy, Sian Harding, Adam P. Wagner, Lisa Miners, Honey Anne-Greco, Laura Lamming, Nigel Lloyd, Katherine E. Brown   +8 more
doaj   +1 more source

Diversity and complexity in neural organoids

FEBS Letters, EarlyView.
Neural organoid research aims to expand genetic diversity on one side and increase tissue complexity on the other. Chimeroids integrate multiple donor genomes within single organoids. Self‐organising multi‐identity organoids, exogenous cell seeding, or enforced assembly of region‐specific organoids contribute to tissue complexity.
Ilaria Chiaradia, Madeline A. Lancaster
wiley   +1 more source