Results 91 to 100 of about 25,067,618 (293)

Health belief model predicts adherence to CPAP before experience with CPAP [PDF]

, 2008
Adherence to continuous positive airway pressure (CPAP) therapy for obstructive sleep apnoea (OSA) is often poor. Biomedical indices explain little of the variance in CPAP use.
Oei, T., T. Oei, Olsen, Sara L., Douglas, James A., Oei, Tian, J. Douglas, Olsen, S., Smith, S., S. Olsen, Douglas, J., S. Smith, Smith, Simon S.   +11 more
core   +1 more source

Pharmacological chromatin remodeling enhances response to estrogen therapy in ER+ breast cancer

Molecular Oncology, EarlyView.
Estrogen therapy elicits clinical benefit in ~ 30% of patients with endocrine‐resistant estrogen receptor (ER)‐positive breast cancer. Based on findings that ER transcriptional activation underlies response to estrogen therapy, we tested the effects of epigenetic dysregulation via pharmacological inhibition of histone deacetylases (HDACi).
Anneka L. Johnson Thomas, Barbara Karakyriakou, Patricia C. Muskus, Alyssa M. Roberts, Justin Rendleman, Alexa Warren, Hanxu Lu, Kimberly A. Birmingham, Malone K. Friedman, Abigail E. Goen, Huijuan Yang, Owen M. Wilkins, Fred W. Kolling, Eugene Demidenko, Julie M. Jorns, Brock C. Christensen, Todd W. Miller   +16 more
wiley   +1 more source

PANoptosis in the pathogenesis of myelodysplastic syndromes

Molecular Oncology, EarlyView.
PANoptosis, a combination of three types of programmed cell death, is mediated by a large protein complex called a PANoptosome. In healthy bone marrow hematopoietic cells, PANoptosis is restricted by inhibitory signaling. In MDS, bone marrow cells become sensitive to the PANoptotic stimuli due to the aberrant inactivation of inhibitory signaling or ...
Rohit Thalla, Jyoti Lamichhane, Cameron Lewis, Peter Breslin, Jiwang Zhang   +4 more
wiley   +1 more source

Effect of a Health Belief Model-based education program on patients’ belief, physical activity, and serum uric acid: a randomized controlled trial

, 2018
Chunhai Shao,1,* Jiwei Wang,2,* Jingfang Liu,1 Fang Tian,1 Hua Li3 1Department of Nutrition, Huashan Hospital, Fudan University, Shanghai, People’s Republic of China; 2Key Laboratory of Health Technology Assessment of Ministry of Health, School of
Li H, Liu J, Tian F, Wang J, Shao C
core  

Castration‐resistant prostate cancer cells are addicted to the high activity of cyclin‐dependent kinase 2

Molecular Oncology, EarlyView.
We show that emergence of castration‐resistant prostate (CRPC) is associated with significant upregulation of cyclins that positively regulate cyclin‐dependent kinase 2 (CDK2) and concomitant downregulation of CDK4 cyclins. This renders CRPC cells dependent on the high activity of CDK2, and CDK2 inhibitors synergistically sensitize CRPC cells to both ...
Joyeeta Chatterjee, Alessia Marin, Shivani Yalala, Harri M. Itkonen   +3 more
wiley   +1 more source

Validation of the Indonesian version of Champion’s Health Belief Model Scale for breast self-examination

, 2018
Triana Kesuma Dewi Department of Clinical Psychology and Mental Health, Faculty of Psychology, Airlangga University, Surabaya, East Java, Indonesia Purpose: The present study aimed to adapt and determine the psychometric properties of the Indonesian ...
Dewi TK
core  

Mechanisms and therapeutic opportunities of the ribotoxic stress response in cancer

Molecular Oncology, EarlyView.
Cancer cells' high translational demand creates opportunities to therapeutically target ribosome function. Ribosome stalling and collisions activate ZAKα and the ribotoxic stress response (RSR), which can trigger rapid, p53‐independent apoptosis in cancer.
Anastassiya Kim, Maryam Aslam, Elouise Torruella, Alphons Sony, Asif Rahman, Simira Smith, Columba de la Parra, Moira Sauane   +7 more
wiley   +1 more source

The effectiveness of education using the health belief model in preventing osteoporosis among female students

, 2013
1-13This study was conducted to determine the impact of education using the Health Belief Model on preventing osteoporosis among female students. This interventional study [quasi-experimental] was performed on 45 female students aged 15-16 years old who ...
Karimizarchi, A., Farokhian , A., Haji Amini, Z., Tavakoli, R., Rahmati Najarkolaei , F., Sanaeinasab, H.   +5 more
core  

The health belief model

, 2023
Development of the health belief model (HBM) In the 1950s US public health researchers began developing psychological models designed to enhance the effectiveness of health education programmes (Hochbaum, 1958). Demographic factors such as socio-economic
Charles Abraham (13056234), P Sheeran (13348344)   +1 more
core  

Profiling neoadjuvant therapy response in rectal cancer using meta‐analysis of publicly available transcriptomic RNA‐seq datasets

Molecular Oncology, EarlyView.
This study integrates publicly available transcriptomic datasets to identify molecular signatures associated with response to neoadjuvant chemoradiotherapy in locally advanced rectal cancer. By analyzing a combination of multiple cohorts with bioinformatics approaches, we reveal biological pathways and immune‐related features that may improve ...
Aleksandra Stanojevic, Rafael Stroggilos, Mladen Marinkovic, Ana Djuric, Suzana Stojanovic‐Rundic, Radmila Jankovic, Sergi Castellvi‐Bel, Remond J.A. Fijneman, Antonia Vlahou, Jerome Zoidakis, Milena Cavic   +10 more
wiley   +1 more source