Results 91 to 100 of about 5,137,646 (317)

Circular RNA expression landscapes in myelodysplastic neoplasms: Associations with mutational signatures and disease progression

open access: yesMolecular Oncology, EarlyView.
In this explorative study, the abundance of circular RNA molecules in bone marrow stem cells was found to be elevated in patients with high‐risk myelodysplastic neoplasms, and to be associated with an increased risk of progression to acute myeloid leukemia.
Eileen Wedge   +17 more
wiley   +1 more source

Other title: Health Values Forum Project

open access: yes, 1993
"June 11, 1993."; "To: Joan Lewerenz, Administrator Program Services, Division of Medical Services, Department of Social and Rehabilitation Services. From: Barbara Langner, Executive Director, Kansas Commission on the Future of Health Care, Inc.""We have
Kansas Commission on the Future of Health Care, Inc.
core  

Housing: Primary Health Care Issue

open access: yesNursing Praxis in Aotearoa New Zealand, 1988
Public Health Nurses in inner city Auckland are seeing increasing hardship due to deteriorating rental accommodation, high rents, overcrowding and lengthy stays in unhealthy conditions.  They see housing as a primary health care issue.
Annette Mortensen
doaj  

Primary care provision for mental health

open access: yesNew Zealand Medical Student Journal, 2020
The treatment of mental illness in New Zealand has seen a steady transition from institutionalised to community-based care, from the mental institutions of the late 19th century to the service-based facilities we see today.
Samantha Murton
doaj  

COMP–PMEPA1 axis promotes epithelial‐to‐mesenchymal transition in breast cancer cells

open access: yesMolecular Oncology, EarlyView.
This study reveals that cartilage oligomeric matrix protein (COMP) promotes epithelial‐to‐mesenchymal transition (EMT) in breast cancer. We identify PMEPA1 (protein TMEPAI) as a novel COMP‐binding partner that mediates EMT via binding to the TSP domains of COMP, establishing the COMP–PMEPA1 axis as a key EMT driver in breast cancer.
Konstantinos S. Papadakos   +6 more
wiley   +1 more source

Pre‐analytical optimization of cell‐free DNA and extracellular vesicle‐derived DNA for mutation detection in liquid biopsies

open access: yesMolecular Oncology, EarlyView.
Pre‐analytical handling critically determines liquid biopsy performance. This study defines practical best‐practice conditions for cell‐free DNA (cfDNA) and extracellular vesicle–derived DNA (evDNA), showing how processing time, storage conditions, tube type, and plasma input volume affect DNA integrity and mutation detection.
Jonas Dohmen   +11 more
wiley   +1 more source

Engineered extracellular vesicles enriched with the miR‐214/199a cluster enhance the efficacy of chemotherapy in ovarian cancer

open access: yesMolecular Oncology, EarlyView.
Loss of the miR‐214/199a cluster is associated with recurrence in ovarian cancer. Engineered small extracellular vesicles (m214‐sEVs) elevate miR‐214‐3p/miR‐199a‐5p in tumor cells, suppress β‐catenin, TLR4, and YKT6 signaling, reprogram tumor‐derived sEV cargo, reduce chemoresistance and migration, and enhance carboplatin efficacy and survival in ...
Weida Wang   +12 more
wiley   +1 more source

2004 Ohio minority health profile

open access: yes, 2006
Title from PDF t.p. (viewed on Aug. 16, 2007).; "To protect and improve the health of all Ohioans"--Cover.; "March 2005."; Harvested from the web on 8/17/07Table of contents, executive summary, Introduction (1 file) -- Demographics (2 files) -- Mortality
Tyner-Onyeaghor, Linda.   +1 more
core  

Integrating child eye health within primary health care: a case study

open access: yesCommunity Eye Health Journal, 2018
Few children have access to specialised eye care in Tanzania. However, ten simple activities have been shown to reduce the risk of childhood blindness and eye disease dramatically.
Milka Mafwiri   +2 more
doaj  

Interrogating the immune landscape of microsatellite stable RAS‐mutated colon cancer

open access: yesMolecular Oncology, EarlyView.
COLOSSUS project RAS‐mutated MSS colon cancer study explored transcriptomics and immune cell density by immunohistochemistry (IHC), Immunoscore (IS), ISIC/TuLIS scores, mutation counts, and detected different prevalences but similar microenvironment composition across immune markers with clinical relevance for future immunotherapy combination ...
Rodrigo Dienstmann   +61 more
wiley   +1 more source

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