Results 121 to 130 of about 8,126,628 (341)

LHIEM: the Longitudinal Health, Income, and Employment Model [PDF]

open access: yesarXiv
Dynamic microsimulation has long been recognized as a powerful tool for policy analysis, but in fact most major health policy simulations lack path dependency, a critical feature for evaluating policies that depend on accumulated outcomes such as retirement savings, wealth, or debt. We propose LHIEM (the Longitudinal Health, Income and Employment Model)
arxiv  

Peripheral blood leukocyte signatures as biomarkers in relapsed ovarian cancer patients receiving combined anti‐CD73/anti‐PD‐L1 immunotherapy in arm A of the NSGO‐OV‐UMB1/ENGOT‐OV30 trial

open access: yesMolecular Oncology, EarlyView.
Using mass cytometry, we analyzed serial blood samples from patients with relapsed epithelial ovarian cancer (EOC) treated with oleclumab–durvalumab combination immunotherapy in the NSGO‐OV‐UMB1/ENGOT‐OV30 trial. Our analysis identified potential predictive, monitoring, and response biomarkers detectable through liquid biopsy. These findings facilitate
Luka Tandaric   +11 more
wiley   +1 more source

Baylor Health Care System: High-Performance Integrated Health Care [PDF]

open access: yes, 2009
Describes the organization's implementation of a quality infrastructure and its strategies, interventions to improve clinical preventive services, training, and adoption of electronic health records and other quality innovations.
Len M. Nichols, Tom Emswiler
core  

"When I lost it, they dragged me out": How Care Encounters Empower Marginalized Young Adults' Mental Health Care-Seeking [PDF]

open access: yesarXiv
CSCW research has long explored ways to enhance the well-being of marginalized populations. This study examines how young adults with diverse marginalized identities navigate their mental health care-seeking journeys through in-depth interviews and visual elicitation methods. Our research with 18 U.S. participants reveals predominantly \textit{passive}
arxiv  

Analysis of comprehensive genomic profiling of solid tumors with a novel assay for broad analysis in clinical diagnostics

open access: yesMolecular Oncology, EarlyView.
In molecular cancer diagnostics, comprehensive genomic profiling (CGP) is going to replace the small NGS panels since it provides all clinically relevant somatic variants as well as genomic biomarkers with clinical value. Here, we compared two CGP assays and demonstrate that the choice for diagnostic implementation will depend on the specific ...
Guy Froyen   +17 more
wiley   +1 more source

Future developments in health care performance management

open access: yesJournal of Multidisciplinary Healthcare, 2013
Maria Crema, Chiara Verbano Department of Management and Engineering, University of Padova, Vicenza, Italy Abstract: This paper highlights the challenges of performance management in health care, wherein multiple different objectives have to be pursued ...
Crema M, Verbano C
doaj  

Subgroup Identification and Interpretation with Bayesian Nonparametric Models in Health Care Claims Data [PDF]

open access: yesarXiv, 2017
Inpatient care is a large share of total health care spending, making analysis of inpatient utilization patterns an important part of understanding what drives health care spending growth. Common features of inpatient utilization measures include zero inflation, over-dispersion, and skewness, all of which complicate statistical modeling.
arxiv  

Response to neoadjuvant chemotherapy in early breast cancers is associated with epithelial–mesenchymal transition and tumor‐infiltrating lymphocytes

open access: yesMolecular Oncology, EarlyView.
Epithelial–mesenchymal transition (EMT) and tumor‐infiltrating lymphocytes (TILs) are associated with early breast cancer response to neoadjuvant chemotherapy (NAC). This study evaluated EMT and TIL shifts, with immunofluorescence and RNA sequencing, at diagnosis and in residual tumors as potential biomarkers associated with treatment response.
Françoise Derouane   +16 more
wiley   +1 more source

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