Results 261 to 270 of about 9,385,653 (364)

SmallTalk: a novel small‐sized fusion tag for peptide expression and purification

FEBS Open Bio, EarlyView.
The SmallTalk fusion tag allows for the efficient expression and purification of soluble recombinant proteins or peptides in Escherichia coli. Testing with SmallTalk‐GFP confirmed that the proteins were soluble and folded correctly, while SmallTalk‐Bin1b maintained its antimicrobial activity against various bacterial isolates. This streamlined workflow
Atika Tariq, Nestor G. Casillas‐Vega, Alma Gomez‐Loredo, Xristo Zarate   +3 more
wiley   +1 more source

P757: Validation and implementation of Emedgene variant interpretation and reporting software for clinical genomic testing

Genetics in Medicine Open
Wanqiong Qiao, Dianna Fisk, Caitlin Hale, Pun Wai Tong, Katelyn Weymouth, Caitlin Reavey, Jessica Chonis, Park Young, Huanzhi Shi, Zena Ng, Kevin Dumas, Stephen Ayers, Annette Chen, Yao Yang, Stuart Scott   +14 more
doaj   +1 more source

Health care resource utilization and health care costs among digital weight-loss intervention participants and nonparticipants. [PDF]

Obesity (Silver Spring)
Tak C, Thompson P, Morse JL, McCallum M.
europepmc   +1 more source

DDX3X induces mesenchymal transition of endothelial cells by disrupting BMPR2 signaling

FEBS Open Bio, EarlyView.
Elevated DDX3X expression led to downregulation of BMPR2, a key regulator of endothelial homeostasis and function. Our co‐immunoprecipitation assays further demonstrated a molecular interaction between DDX3X and BMPR2. Notably, DDX3X promoted lysosomal degradation of BMPR2, thereby impairing its downstream signaling and facilitating endothelial‐to ...
Yu Zhang, Jing Wang, De‐Hui Qian, Yang‐Fan Lv, Tian‐Le Cheng, Da‐Peng Wang, Jing Zhang, Ye Fan   +7 more
wiley   +1 more source

Adoption of Artificial Intelligence in the Health Care Sector.

JAMA Health Forum
Nguyen TD, Whaley CM, Simon K, Mehta N, Yu H, McBain RK, Mehrotra A, Cantor JH.   +7 more
europepmc   +1 more source

Editorial: Advancing the science and practice of health care transition. [PDF]

Health Care Transit
Betz CL.
europepmc   +1 more source

Antibiofilm activity of a chionodracine‐derived peptide by NMR‐based metabolomics of cell‐free supernatant of Acinetobacter baumannii clinical strains

FEBS Open Bio, EarlyView.
KHS‐Cnd peptide is able to impair biofilm formation and disaggregate mature biofilms in Acinetobacter baumannii clinical isolates. Differences in extracellular metabolites reflect changes in biofilm metabolism due to KHS‐Cnd treatment. Among the differentially represented extracellular metabolites upon KHS‐Cnd treatment, the significantly altered ...
Fernando Porcelli, Enrico Landi, Francesco Maiurano, Irene Paris, Rosanna Papa, Marco Artini, Laura Selan, Stefano Borocci, Francesco Buonocore, Esther Imperlini   +9 more
wiley   +1 more source

Scope of Nursing Practice in Primary Health Care: defining a way forward. [PDF]

Rev Lat Am Enfermagem
Moreno-Dias B, Bolastig EVC, Puertas-Donoso EB.   +2 more
europepmc   +1 more source

Pathogenic Neurofibromatosis type 1 gene variants in tumors of non‐NF1 patients and role of R1276

FEBS Open Bio, EarlyView.
Somatic variants of the neurofibromatosis type 1 (NF1) gene occur across neoplasms without clinical manifestation of the disease NF1. We identified emerging somatic pathogenic NF1 variants and hotspots, for example, at the arginine finger 1276. Those missense variants provide fundamental information about neurofibromin's role in cancer.
Mareike Selig, Swanhild Lohse, Sara Elahi, Nils Hartmann, Stefanie Deckert, Shutian Si, Alexander Desuki, Anja Harder   +7 more
wiley   +1 more source

AI in Health Care Service Quality: Systematic Review. [PDF]

JMIR AI
Alghareeb E, Aljehani N.
europepmc   +1 more source