Results 41 to 50 of about 8,126,628 (341)
Characteristics of the Kelch domain containing (KLHDC) subfamily and relationships with diseases
FEBS Letters, EarlyView.The Kelch protein superfamily includes 63 members, with the KLHDC subfamily having 10 proteins. While their functions are not fully understood, recent advances in KLHDC2's structure and role in protein degradation have highlighted its potential for drug development, especially in PROTAC therapies.
Courtney Pilcher +6 more
wiley +1 more source
Making tau amyloid models in vitro: a crucial and underestimated challenge
FEBS Letters, EarlyView.This review highlights the challenges of producing in vitro amyloid assemblies of the tau protein. We review how accurately the existing protocols mimic tau deposits found in the brain of patients affected with tauopathies. We discuss the important properties that should be considered when forming amyloids and the benchmarks that should be used to ...
Julien Broc, Clara Piersson, Yann Fichou
wiley +1 more source
Rationalising health care provision under market incentives: experimental evidence from south Africa [PDF]
, 2020 Unnecessary medical treatments place a significant burden on health systems striving for universal health coverage (UHC). This thesis studies inappropriate treatment incentives in the private sector in South Africa, where plans to implement a national ...
Sripathy, Arthika
core
Annals of Agricultural and Environmental Medicine, 2018 Objective To examine disparities in access to the public in Poland, in association of the resources of health care, socio-economic development of Provinces and their level of urbanization. Material and Methods The Provinces were divided into four groups,
Ewa Zienkiewicz +2 more
doaj +1 more source
The Society of Cancer Precision Medicine of Chinese Anti-Cancer Association
Chinese Journal of Lung Cancer, 2023 RNA-based next-generation sequencing (NGS) has been recommended as a method for detecting fusion genes in non-small cell lung cancer (NSCLC) according to clinical practice guidelines and expert consensus.
China Primary Health Care Foundation Tumor Precision Diagnosis and Treatment Committee +1 more
doaj +1 more source
FEBS Letters, EarlyView.α2 → 8 polysialic acid elicits poor immunogenicity. Small‐angle scattering shows a supramolecular structure with parallel‐chain binding, although in different forms at μm and mm calcium. The major histocompatibility complex requires molecular weights around 2000 Da to produce antibodies, and 2000 Da polysialic oligomers will bind in these structures ...
Kenneth A. Rubinson
wiley +1 more source
IC 053 Guide to Texas Health Care Association Records, 1985-1986 [PDF]
, 1985 The Texas Health Care Association records is very small and consists only of the October/November 1985 and December/January 1985-1986 issues of Caring , the news magazine of the Texas Health Care Association.
Texas Health Care Association
core +1 more source
The power of microRNA regulation—insights into immunity and metabolism
FEBS Letters, EarlyView.MicroRNAs are emerging as crucial regulators at the intersection of metabolism and immunity. This review examines how miRNAs coordinate glucose and lipid metabolism while simultaneously modulating T‐cell development and immune responses. Moreover, it highlights how cutting‐edge artificial intelligence applications can identify miRNA biomarkers ...
Stefania Oliveto +2 more
wiley +1 more source
Uncertainty and the Welfare Economics of Medical Care: An Austrian Rebuttal-Part 3
Southwest Respiratory and Critical Care Chronicles, 2017 Part 3 concludes the rebuttal to the argument that health care is special and that markets cannot properly distribute health care. Part 1 was a general discussion of the argument made by Kenneth Arrow.
Berdine Gilbert
doaj +1 more source
Integrating Machine Learning with Discrete Event Simulation for Improving Health Referral Processing in a Care Management Setting [PDF]
arXiv, 2022 Post-discharge care management coordinates patients' referrals to improve their health after being discharged from hospitals, especially elderly and chronically ill patients. In a care management setting, health referrals are processed by a specialized unit in the managed care organization (MCO), which interacts with many other entities including ...
arxiv