In lymphoid organs, antigen recognition and B cell receptor signaling rely on integrins and the cytoskeleton. Integrins act as mechanoreceptors, couple B cell receptor activation to cytoskeletal remodeling, and support immune synapse formation as well as antigen extraction.
Abhishek Pethe, Tanja Nicole Hartmann
wiley +1 more source
International Profiles of Health Care Systems, 2012 [PDF]
This publication presents overviews of the health care systems of Australia, Canada, Denmark, England, France, Germany, Japan, Iceland, Italy, the Netherlands, New Zealand, Norway, Sweden, Switzerland, and the United States.
core
B cells sense external mechanical forces and convert them into biochemical signals through mechanotransduction. Understanding how malignant B cells respond to physical stimuli represents a groundbreaking area of research. This review examines the key mechano‐related molecules and pathways in B lymphocytes, highlights the most relevant techniques to ...
Marta Sampietro+2 more
wiley +1 more source
Do psychological treatments reduce symptoms of post-traumatic stress disorder? Evidence update - Summary of a Cochrane Review [PDF]
Trauma focused cognitive behavioural therapy (TFCBT), eye movement desensitisation and reprocessing (EMDR), stress management, and group TFCBT reduce traumatic symptoms in post-traumatic stress ...
Effective Health Care Research Consortium
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In adults with multimorbidity, does the provision of social care services have an effect on the use of primary care and secondary care health services? [PDF]
Objectives: Health and social care is an area of high policy importance in the UK. Integration of health boards with local authority provided social care in Scotland in 2016 is a major structural change in delivery of care.
Henderson, David
core +3 more sources
Evolutionary interplay between viruses and R‐loops
Viruses interact with specialized nucleic acid structures called R‐loops to influence host transcription, epigenetic states, latency, and immune evasion. This Perspective examines the roles of R‐loops in viral replication, integration, and silencing, and how viruses co‐opt or avoid these structures.
Zsolt Karányi+4 more
wiley +1 more source
Mothers Perception of Health Care Needs of Preterm Neonates in Intensive Care Unit
Background: Family members of the new born admitted to neonatal intensive care unit (NICU) of hospitals are stressed and in are in undue anxiety.
Lavanya Subhashini, Radha MS, Baby GK
doaj +1 more source
Circulating histones as clinical biomarkers in critically ill conditions
Circulating histones are emerging as promising biomarkers in critical illness due to their diagnostic, prognostic, and therapeutic potential. Detection methods such as ELISA and mass spectrometry provide reliable approaches for quantifying histone levels in plasma samples.
José Luis García‐Gimenez+17 more
wiley +1 more source
Immigrants in Health Care: Keeping Americans Healthy Through Care and Innovation [PDF]
Immigrants play an outsized and imperative role in the U.S. health care industry. Combining existing data and profiles of immigrants across the health care spectrum, Immigrants in Health Care: Keeping Americans Healthy Through Care and Innovation ...
Marcia D. Hohn
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Communication and support from health-care professionals to families, with dependent children, following the diagnosis of parental life-limiting illness : a systematic review [PDF]
Background: Communication between parents and their children about parental life-limiting illness is stressful. Parents want support from health-care professionals; however, the extent of this support is not known.
Boland, Jason W., Fearnley, Rachel
core +1 more source