Results 41 to 50 of about 2,369,178 (349)

Long-term medical and productivity costs of severe trauma: Results from a prospective cohort study.

PLoS ONE, 2021
BackgroundThrough improvements in trauma care there has been a decline in injury mortality, as more people survive severe trauma. Patients who survive severe trauma are at risk of long-term disabilities which may place a high economic burden on society ...
Marjolein van der Vlegel, Juanita A Haagsma, Roos J M Havermans, Leonie de Munter, Mariska A C de Jongh, Suzanne Polinder   +5 more
doaj   +1 more source

Characterizing the salivary RNA landscape to identify potential diagnostic, prognostic, and follow‐up biomarkers for breast cancer

Molecular Oncology, EarlyView.
This study explores salivary RNA for breast cancer (BC) diagnosis, prognosis, and follow‐up. High‐throughput RNA sequencing identified distinct salivary RNA signatures, including novel transcripts, that differentiate BC from healthy controls, characterize histological and molecular subtypes, and indicate lymph node involvement.
Nicholas Rajan, Irina Primac, Emre Etlioglu, Laurens Debruyne, Ann Janssen, Magy Sallam, Kevin Tabury, Roel Quintens, Wiebren Tjalma, Mohammed Abderrafi Benotmane   +9 more
wiley   +1 more source

Bridging the gap: Multi‐stakeholder perspectives of molecular diagnostics in oncology

Molecular Oncology, EarlyView.
Although molecular diagnostics is transforming cancer care, implementing novel technologies remains challenging. This study identifies unmet needs and technology requirements through a two‐step stakeholder involvement. Liquid biopsies for monitoring applications and predictive biomarker testing emerge as key unmet needs. Technology requirements vary by
Jorine Arnouts, Senada Koljenović, Elise Daems, Karolien De Wael, Marc Peeters, Léon C. van Kempen, Greetje Vanhoutte, Karen Zwaenepoel, Timon Vandamme   +8 more
wiley   +1 more source

Policy Implications of Freestanding Emergency Departments [PDF]

, 2015
Policymakers have a responsibility to look at both the short- and long-term implications of their decisions. The state’s current fiscal situation, coupled with rising health-care costs makes “budget neutrality” highly desirable in decision-making.
Frazier, Rosyland, Guettabi, Mouhcine
core  

The difficult task of predicting the costs of community-based mental health care. A comprehensive case register study. [PDF]

, 2011
Previous studies have attempted to forecast the costs of mental health care, using clinical and individual variables; the inclusion of ecological measures could improve the knowledge of predictors of psychiatric service utilisation and costs to support ...
Amaddeo, F., Donisi, V., Grigoletti, L., Jones, J., Pertile, R., Salazzari, D., Tansella, M.   +6 more
core   +1 more source

Lifetime Health Care Costs of the Danish Population

Journal of Health Economics and Outcomes Research, 2013
# Objectives Lifetime health care cost is a statistical indicator for expected health care use during the remaining lifetime of an individual. The objective of this study was to estimate the lifetime health care costs for individual gender and age strata.
Jan Sørensen, Rikke Søgaard
doaj  

Hospital care direct costs due to ambulatory care sensitive conditions related to diabetes mellitus in the Mexican public healthcare system

BMC Health Services Research
Background Hospitalizations for ambulatory care sensitive conditions (ACSC) incur substantial costs on the health system that could be partially avoided with adequate outpatient care. Complications of chronic diseases, such as diabetes mellitus (DM), are
Pedro Saturno-Hernández, Estephania Moreno-Zegbe, Ofelia Poblano-Verastegui, Laura del Pilar Torres-Arreola, Arturo C. Bautista-Morales, Cynthya Maya-Hernández, Juan David Uscanga-Castillo, Sergio Flores-Hernández, Patricia María Gómez-Cortez, Waldo Iván Vieyra-Romero   +9 more
doaj   +1 more source

Integrated genomic and proteomic profiling reveals insights into chemoradiation resistance in cervical cancer

Molecular Oncology, EarlyView.
A comprehensive genomic and proteomic analysis of cervical cancer revealed STK11 and STX3 as a potential biomarkers of chemoradiation resistance. Our study demonstrated EGFR as a therapeutic target, paving the way for precision strategies to overcome treatment failure and the DNA repair pathway as a critical mechanism of resistance.
Janani Sambath, Irene A. George, Srikanth S. Manda, Prasanth Ariyannur, Ekta R. Dhawale, Raja Sekhar Kommu, Rajan Datar, Darshana Patil, Vinita Trivedi, Manisha Singh, Kumar Prabhash, Sewanti Limaye, Richa Chauhan, Prashant Kumar   +13 more
wiley   +1 more source

Health care during electricity failure: The hidden costs.

PLoS ONE, 2020
BackgroundSurgery risks increase when electricity is accessible but unreliable. During unreliable electricity events and without data on increased risk to patients, medical professionals base their decisions on anecdotal experience.
Abigail Mechtenberg, Brady McLaughlin, Michael DiGaetano, Abigail Awodele, Leslie Omeeboh, Emmanuel Etwalu, Lydia Nanjula, Moses Musaazi, Mark Shrime   +8 more
doaj   +1 more source

Tumor and germline testing with next generation sequencing in epithelial ovarian cancer: a prospective paired comparison using an 18‐gene panel

Molecular Oncology, EarlyView.
Genetic testing in epithelial ovarian cancer includes both germline and tumor‐testing. This approach often duplicates resources. The current prospective study assessed the feasibility of tumor‐first multigene testing by comparing tumor tissue with germline testing of peripheral blood using an 18‐gene NGS panel in 106 patients.
Elisabeth Spenard, Cristina Mitric, Melanie Care, Tracy L. Stockley, Raymond H. Kim, Jeanna McCuaig, Blaise Clarke, Laura Ranich, Clare Sheen, Sarah E. Ferguson, Liat Hogen, Taymaa May, Marcus Q. Bernardini   +12 more
wiley   +1 more source