Results 41 to 50 of about 2,382,440 (303)

LDAcoop: Integrating non‐linear population dynamics into the analysis of clonogenic growth in vitro

open access: yesMolecular Oncology, EarlyView.
Limiting dilution assays (LDAs) quantify clonogenic growth by seeding serial dilutions of cells and scoring wells for colony formation. The fraction of negative wells is plotted against cells seeded and analyzed using the non‐linear modeling of LDAcoop.
Nikko Brix   +13 more
wiley   +1 more source

Environmental, Health and Health¬care Costs

open access: yesمدیریت اطلاعات سلامت, 2015
Introduction: Environment pollution affects the private and public health sector. In this study, the impacts of environmental pollution on healthcare costs and on the out of pocket expenditure and also the impact of pollution on public health have been ...
Yousef Mohammadzadeh   +2 more
doaj  

Primary care as a means of decreasing health care costs

open access: yesHealth SA Gesondheid: Journal of Interdisciplinary Health Sciences, 2004
The study was focussed at furthering the health objectives of the Government’s Reconstruction and Development Programme in the area of primary care. Opsomming Die studie was gemik op die bevordering van die gesondheidsdoelwitte van die regering se ...
Martie M van Deventer   +2 more
doaj   +1 more source

Massachusetts Miracle or Massachusetts Miserable: What the Failure of the "Massachusetts Model"Tells Us about Health Care Reform [PDF]

open access: yes, 2009
When Massachusetts passed its pioneering health care reforms in 2006, critics warned that they would result in a slow but steady spiral downward toward a government-run health care system.
Michael D. Tanner
core  

Crucial parameters for precise copy number variation detection in formalin‐fixed paraffin‐embedded solid cancer samples

open access: yesMolecular Oncology, EarlyView.
This study shows that copy number variations (CNVs) can be reliably detected in formalin‐fixed paraffin‐embedded (FFPE) solid cancer samples using ultra‐low‐pass whole‐genome sequencing, provided that key (pre)‐analytical parameters are optimized.
Hanne Goris   +10 more
wiley   +1 more source

Influence of deprivation on health care use, health care costs, and mortality in COPD

open access: yesInternational Journal of COPD, 2018
Peter F Collins,1–3 Rebecca J Stratton,1 Ramesh J Kurukulaaratchy,4,5 Marinos Elia1 1NIHR Nutrition Biomedical Research Centre, Faculty of Medicine, University of Southampton, Southampton General Hospital, University Hospital Southampton NHS ...
Collins PF   +3 more
doaj  

Combining antibody conjugates with cytotoxic and immune‐stimulating payloads maximizes anti‐cancer activity

open access: yesMolecular Oncology, EarlyView.
Methods to improve antibody–drug conjugate (ADC) treatment durability in cancer therapy are needed. We utilized ADCs and immune‐stimulating antibody conjugates (ISACs), which are made from two non‐competitive antibodies, to enhance the entry of toxic payloads into cancer cells and deliver immunostimulatory agents into immune cells.
Tiexin Wang   +3 more
wiley   +1 more source

Health Care Opinion Leaders' Views on Slowing the Growth of Health Care Costs [PDF]

open access: yes, 2009
Presents results of a survey of experts on the need to slow U.S. healthcare spending growth and on support for cost-reduction strategies, including payment reform and creating a center for comparative effectiveness, as proposed by the Obama ...
Karen Davis   +2 more
core  

Colorectal cancer‐derived FGF19 is a metabolically active serum biomarker that exerts enteroendocrine effects on mouse liver

open access: yesMolecular Oncology, EarlyView.
Meta‐transcriptome analysis identified FGF19 as a peptide enteroendocrine hormone associated with colorectal cancer prognosis. In vivo xenograft models showed release of FGF19 into the blood at levels that correlated with tumor volumes. Tumoral‐FGF19 altered murine liver metabolism through FGFR4, thereby reducing bile acid synthesis and increasing ...
Jordan M. Beardsley   +5 more
wiley   +1 more source

Long-term medical and productivity costs of severe trauma: Results from a prospective cohort study.

open access: yesPLoS ONE, 2021
BackgroundThrough improvements in trauma care there has been a decline in injury mortality, as more people survive severe trauma. Patients who survive severe trauma are at risk of long-term disabilities which may place a high economic burden on society ...
Marjolein van der Vlegel   +5 more
doaj   +1 more source

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