Results 211 to 220 of about 2,110,789 (346)

A Randomized Trial of Two Remote Health Care Delivery Models on the Uptake of Genetic Testing and Impact on Patient-Reported Psychological Outcomes in Families With Pancreatic Cancer: The Genetic Education, Risk Assessment, and Testing (GENERATE) Study [PDF]

Nicolette J. Rodriguez, C. Sloane Furniss, Matthew B. Yurgelun, Chinedu Ukaegbu, Pamela E. Constantinou, Ileana Fortes, Alyson Caruso, Alison Schwartz, Jill E. Stopfer, Meghan Underhill‐Blazey, Barbara Kenner, Scott H. Nelson, Sydney Okumura, Alicia Y. Zhou, Tara B. Coffin, Hajime Uno, Miki Horiguchi, Allyson J. Ocean, Florencia McAllister, Andrew M. Lowy, Alison P. Klein, Lisa Madlensky, Gloria M. Petersen, Judy E. Garber, Scott M. Lippman, Michael Goggins, Anirban Maitra, Sapna Syngal   +27 more
openalex   +1 more source

Patient acceptability and usability of a self-administered electronic patient-reported outcome assessment in HIV care: relationship with health behaviors and outcomes

, 2020
Rob J. Fredericksen, Barbara N Harding, Stephanie A. Ruderman, Liz Morton, G. Barnes, William B. Lober, Emma Fitzsimmons, Robin M. Nance, Bridget M. Whitney, Joseph A. Delaney, William C. Mathews, James H. Willig, Paul K. Crane, Heidi M. Crane   +13 more
openalex   +2 more sources

PARP inhibition and pharmacological ascorbate demonstrate synergy in castration‐resistant prostate cancer

Molecular Oncology, EarlyView.
Pharmacologic ascorbate (vitamin C) increases ROS, disrupts cellular metabolism, and induces DNA damage in CRPC cells. These effects sensitize tumors to PARP inhibition, producing synergistic growth suppression with olaparib in vitro and significantly delayed tumor progression in vivo. Pyruvate rescue confirms ROS‐dependent activity.
Nicolas Gordon, Peter T. Gallagher, Orly I. Richter, Neermala Poudel Neupane, Amy C. Mandigo, Jennifer J. McCann, Emanuela Dylgjeri, Irina Vasilevskaya, Christopher McNair, Channing J. Paller, Wm. Kevin Kelly, Karen E. Knudsen, Matthew J. Schiewer, Ayesha A. Shafi   +13 more
wiley   +1 more source

Assessment of mental health outcomes and associated factors among workers in community-based HIV care centers in the early stage of the COVID-19 outbreak in Mali

, 2020
Luis Sagaon‐Teyssier, Aliou Kamissoko, Adam Yattassaye, Fodié Diallo, Daniela Rojas Castro, Rosemary M. Delabre, Fabrice Pouradier, Gwenaëlle Maradan, Michel Bourrelly, Mamadou Cissé, Laurent Vidal, Bintou Dembélé Keïta, Bruno Spire   +12 more
openalex   +1 more source

LDAcoop: Integrating non‐linear population dynamics into the analysis of clonogenic growth in vitro

Molecular Oncology, EarlyView.
Limiting dilution assays (LDAs) quantify clonogenic growth by seeding serial dilutions of cells and scoring wells for colony formation. The fraction of negative wells is plotted against cells seeded and analyzed using the non‐linear modeling of LDAcoop.
Nikko Brix, Daniel Samaga, Katharina Gehr, Benedek Dankó, Mohamed Schumann, Guido Drexler, Ahmed Alnatsha, Georg Beyer, Ujjwal Mahajan, Martin Selmansberger, Julia Mayerle, Claus Belka, Horst Zitzelsberger, Kirsten Lauber   +13 more
wiley   +1 more source

A guided chatbot-based psychological intervention for psychologically distressed older adolescents and young adults: a randomised clinical trial in Jordan. [PDF]

NPJ Digit Med
Bryant RA, de Graaff AM, Habashneh R, Fanatseh S, Keyan D, Akhtar A, Abualhaija A, Faroun M, Aqel IS, Dardas L, Afar H, Servili C, Hadzi-Pavlovic D, van Ommeren M, Carswell K.   +14 more
europepmc   +1 more source

Outcomes of guidelines from health technology assessment organizations in community-based primary care: a systematic mixed studies review [PDF]

Ashkan Baradaran, Raymond Tolentino, Roland Grad, Isabelle Ganache, Geneviève Gore, Samira Abbasgholizadeh Rahimi, Pierre Pluye   +6 more
openalex   +1 more source

Therapeutic strategies for MMAE‐resistant bladder cancer through DPP4 inhibition

Molecular Oncology, EarlyView.
We established monomethyl auristatin E (MMAE)‐resistant bladder cancer (BC) cell lines by exposure to progressively increasing concentrations of MMAE in vitro. RNA sequencing showed DPP4 expression was increased in MMAE‐resistant BC cells. Both si‐DPP4 and the DPP4 inhibitor sitagliptin suppressed the viability of MMAE‐resistant BC cells.
Gang Li, Shuichi Tatarano, Hirofumi Yoshino, Saeki Saito, Mitsuhiko Tominaga, Junya Arima, Ikumi Fukuda, Takashi Sakaguchi, Ryosuke Matsushita, Yasutoshi Yamada, Hideki Enokida   +10 more
wiley   +1 more source

Avaliação do processo de atendimento a pacientes portadores de doença crônico-degenerativa em uma unidade básica de saúde

Revista de Saúde Pública
Avalia-se o desempenho de ações de saúde desenvolvidas em uma unidade básica de saúde, relativas ao controle da hipertensão arterial sistêmica (HAS) enquanto estratégia de redução de morbi-mortalidadc por doença cardiovascular baseada no "enfoque de ...
Arnaldo Sala, Diane D. Cohen, Ana S. W. Dalmaso, Ângela M. M. Lima, Ricardo R. Teixeira   +4 more
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