Results 61 to 70 of about 14,354,587 (240)
ABSTRACT Adeno‐associated viruses (AAVs) are the leading vectors for in vivo gene therapy, fueling a growing demand for scalable and robust biomanufacturing processes. Yet, the impact of cell lysis conditions on the performance of midstream and downstream unit operations across serotypes remains poorly characterized.
Arianna Minzoni +20 more
wiley +1 more source
Benefits and Challenges of Policy Options in Rationing the Hospital Radiology Services: A Case Study
Objective: In many countries, limiting the financial and budgetary resources is a challenge in the health system. One of the most costly parts of the health system is undoubtedly the radiology department of hospitals.
Hasan Jafari +5 more
doaj
Background In rationing decisions in health, many criteria like costs, effectiveness, equity and feasibility concerns play a role. These criteria stem from different disciplines that all aim to inform health care rationing decisions, but a single ...
Tromp Noor, Baltussen Rob
doaj +1 more source
The influence of circadian variables on ecotoxicology metabolomics
ABSTRACT Ecotoxicologists are using metabolomics increasingly to gain insight into toxicological mechanisms and sublethal effects of chemical exposures. Metabolomics offers a sensitive multi‐parameter approach that can detect biochemical responses not obvious using apical and behavioural endpoints.
Ryan I. Lester +3 more
wiley +1 more source
Moral Judgments in the Rationing of Health Care Resources
Social workers, physicians, and nurses from a major urban teaching hospital were assessed and compared regarding their attitudes toward the rationing of health care.
McLellan, Linda J. +3 more
core +1 more source
ABSTRACT Small enterprises (SEs) constitute a major component of economic systems, and their socio‐environmental commitment is critical for promoting societal well‐being. This paper examines the direct effect of sound financial practices on socio‐environmental commitment and evaluates the mediating role of financial constraints—specifically debt and ...
Marcos Álvarez‐Espiño +2 more
wiley +1 more source
A idade como critério de limitação terapêutica. A evidência e os enviesamentos
Resumo: A idade como critério de limitação de determinadas intervenções terapêuticas tem estado na origem de um dos debates bioéticos da actualidade. O aumento da esperança média de vida à nascença e o crescente envelhecimento da população, por um lado ...
Filipe Monteiro
doaj +1 more source
Who and how should participate in health care priority setting? Evidence from a Portuguese survey [PDF]
This article provides highlights of the evolution of the health care rationing debate towards a more transparent and open approach involving public participation. Discretionary models that have dominated health sector decision-making are being questioned
Micaela M. Pinho +2 more
core
Climate Stress Testing on European SME Securitised Loans Under Climate Mitigation Scenarios
ABSTRACT Assessing the future impact of climate risks on the probability of default (PD) of small and medium enterprises (SMEs) is challenging due to limited disclosure, policy uncertainty and exposure to physical risks. This paper addresses this gap by integrating macroeconomic variables from the Network for Greening the Financial System (NGFS ...
Luca Zanin, Raffaella Calabrese
wiley +1 more source
Hands on the Patient with Eyes on the Budget
In 1993, Marcia Angell wrote an article highlighting the growing trend of doctors being asked to function as “double agents,” meaning physicians had to weigh their duty to patient care against the social costs of medical services.[1] This situation of ...
Sebastian Agredo
doaj +1 more source

