Results 31 to 40 of about 60,764 (306)
Advanced Healthcare Materials, EarlyView.Neural cell–derived small extracellular vesicles (sEVs) are emerging as pivotal mediators in neurodegenerative diseases, exerting both pathogenic and therapeutic functions. This review synthesizes current evidence on how sEVs from distinct neural cell types regulate neurodegeneration, neuroprotection, biomarker discovery, and targeted drug delivery ...
Muhammad Waqas Salim +4 more
wiley +1 more source
A comparison between raw and predicted mortality in a paediatric intensive care unit in South Africa
BMC Research Notes, 2018 Objective Paediatric intensive care resources are limited in sub-Saharan Africa. The mortality rate in a combined Paediatric/Neonatal Intensive Care Unit in Johannesburg, South Africa was almost double that in a dedicated paediatric intensive care unit ...
Daynia Elizabeth Ballot +3 more
doaj +1 more source
Priorities Towards Fair Allocation of Ventilators During COVID-19 Pandemic: A Delphi Study
Frontiers in Medicine, 2022 BackgroundCOVID-19 pandemic has resulted in severe shortage in vital resources, including invasive mechanical ventilators. The current imbalance between demand and supply of mechanical ventilators has called for investigations on the fair allocation of ...
Seyyed-Hadi Ghamari +4 more
doaj +1 more source
Advanced Materials Technologies, EarlyView.This work establishes a framework for high‐resolution printed interconnects by coupling e‐jet printing control, multilayer deposition, and sintering optimization. Ink properties and printing speed influence particle stacking, while different sintering atmospheres drive distinct microstructural evolution.
Kaifan Yue +6 more
wiley +1 more source
Tunable 3D‐Printed Static Mixers for Gradient Bioprinting With High Cell Viability
Advanced Materials Technologies, EarlyView.ABSTRACT The fabrication of native tissue‐like structures with gradual transitions in material properties, cell types, and growth factors remains a major challenge in biofabrication due to the lack of suitable methods. Mimicking the hierarchical organization of living tissues is essential for functional models, yet creating gradient, multimaterial ...
Florian Hofmann +9 more
wiley +1 more source
Canadian Geriatrics Journal, 2021 COVID-19 pandemic has resulted in a significant increase in deaths in long-term care homes (LTCH). People with dementia living in LTCHs represent one of the most frail and marginalized populations in Canada.
Sharon Kaasalainen +3 more
doaj +1 more source
The Elderly and Health Care Rationing [PDF]
, 2009 [Excerpt] “The allocation of health care resources involves a societal determination of what resources should be devoted to a particular program. The allocation process is typically performed on a ―macro‖ level, with allocation decisions often affecting ...
Smith, George P., II
core +2 more sources
Advanced Science, EarlyView.ABSTRACT Hepatocellular carcinoma (HCC) remains a significant clinical challenge due to the limited efficacy of conventional treatments like surgery, radiofrequency ablation (RFA), and transarterial embolization (TAE). Here, we develop an innovative TAE and immunothermal therapy strategy based on smartly assembled near‐micron layered double hydroxide ...
Qitao Hu +12 more
wiley +1 more source
The “Elderly” in Medicine: Ethical Issues Surrounding This Outdated and Discriminatory Term
Inquiry: The Journal of Health Care Organization, Provision, and Financing, 2019 The objective of this study was to investigate and describe how the use of the term “elderly” contributes to bias and problems within the medical system. A systematic review of the relevant literature and history was conducted.
Javad Hekmat-panah MD
doaj +1 more source
Advanced Science, EarlyView.ZDHHC17 palmitoylates CDK4, which together with TRAF6‐mediated ubiquitination, drives cell cycle progression and immune surveillance, revealing a rational combination of CDK4 inhibitors with immune checkpoint blockers for ZDHHC17‐driven cancers. ABSTRACT Uncontrolled cell cycle progression is a hallmark of cancer, tightly regulated by both intrinsic ...
Zekang Wang +7 more
wiley +1 more source