Dynamic Regulation of Endogenous Transcription Factor Hubs at Single‐Molecule Resolution
This study combines single‐molecule microscopy and genome editing to characterize the dynamic behaviors of endogenous oncofusion transcription factor EWS::FLI1 in Ewing sarcoma cells. EWS::FLI1 forms neomorphic hubs that dynamically assemble and dissolve. The hubs are regulated during mitosis, by RNA, and by specific chemicals.
Shawn Yoshida +4 more
wiley +1 more source
High‐throughput quantum‐mechanical simulations reveal that amorphous carbon undergoes shear‐driven structural transformation into aromatic, graphene‐like interfaces. This mechanochemical process is governed by dopant chemistry: dopants with valency less than four promote the emergence of superlow‐friction amorphous graphene, whereas tetra‐valent ...
Takuya Kuwahara +4 more
wiley +1 more source
How Can China's New Health Care Reform Promote the Balance of Interest Game?-Based on Game Evolution and Simulation Analysis. [PDF]
Gong H, Wang X, Zhang T, Li J, Chen B.
europepmc +1 more source
A Supramolecular Reversible and Anisotropic Conductive Adhesive for Flexible Electronics
Supramolecular network‐based nanocomposites are developed as a stretchable conductive adhesive for flexible electronics. It's as convenient as traditional solders and constructs anisotropic conductive and robust stretchable connections among diverse soft/rigid materials.
Tongtong Li +8 more
wiley +1 more source
Background Early initiation of therapy can be crucial for the course of mental health problems. Among other new care elements, the structural reform of the outpatient psychotherapy system in Germany introduced psychotherapeutic consultations to enable ...
Sandra Werner +18 more
doaj +1 more source
Urinary proteomics combined with home blood pressure telemonitoring for health care reform trial-First progress report. [PDF]
Chori BS +27 more
europepmc +1 more source
Lattice Distortion‐Driven Metal Exsolution in Perovskite Oxides
This study elucidates the mechanism of lattice distortion‐driven exsolution through a combination of computational simulations and experimental approaches. Lattice distortion facilitates the formation of oxygen vacancies and subsequent metal segregation, thereby enhancing the exsolution behavior.
Yo Han Kim +5 more
wiley +1 more source
Primary health care in China: A decade of development after the 2009 health care reform. [PDF]
Wu Y +11 more
europepmc +1 more source
Thermal Spin Coated PbS QD SWIR Imager for Non‐Invasive Glucose Monitoring
Thermal spin‐coating enables controlled film formation of PbS quantum dots, leading to denser packing, reduced defect‐assisted transport, and improved carrier extraction. The resulting photodetectors exhibit suppressed dark current, enhanced responsivity, and faster response.
Lei Rao +9 more
wiley +1 more source
3D‐Printed Magnetoelectronics for Interactive Appliances and Self‐Aware 4D‐Printed Mechatronics
3D‐printed magnetoelectronics integrate high‐performance magnetic field sensing directly into complex structural components. Flexible spring and cross‐shaped sensors exhibit giant magnetoimpedance and 3D Hall sensing for vector field reconstruction. Applications include smart‐home switches, robotic joysticks, volumetric magnetometers, and self‐aware 4D‐
Eduardo Sergio Oliveros‐Mata +5 more
wiley +1 more source

