Results 171 to 180 of about 15,275,318 (300)

Electronic Patient-Reported Health-Related Quality of Life Trajectories in ICU Survivors: A Multicentre Pilot Study-Within-a-Trial Protocol. [PDF]

Acta Anaesthesiol Scand
Battistelli EZ, Kaas-Hansen BS, Granholm A, Plovsing RTR, Rasmussen BS, Perner A, Kjær MN.   +6 more
europepmc   +1 more source

Intrapatient tumour heterogeneity and clonal evolution in an autopsy study of metastatic salivary gland cancer

Molecular Oncology, EarlyView.
Tumour heterogeneity and clonal evolution of metastatic salivary gland cancer were evaluated in two patients with adenoid carcinoma and one patient with myoepithelial carcinoma. Radiology‐guided autopsy enabled multi‐region sampling (total samples n = 149), followed by whole‐genome sequencing and phylogenetic reconstruction (17 tumour samples, 4–7 per ...
Gerben Lassche, Niels J. van Ruitenbeek, Charlotte Adang, Luke O'Gorman, Pui Yuen Lee, Willemijn M. Klein, Adriana C. H. van Engen‐van Grunsven, Jack A. Schalken, Sander Bervoets, Gerald W. Verhaegh, Carla M. L. van Herpen   +10 more
wiley   +1 more source

Hospital-acquired infections worldwide in relation to Gross Domestic Product: A global ecological analysis of point-prevalence surveys. [PDF]

PLOS Glob Public Health
Etcheverry E, Vanhems P, Dessemon J, Elias C, Saadatian-Elahi M.   +4 more
europepmc   +1 more source

Somatostatin receptor 4 (SSTR4) is a tumor suppressor in cutaneous and head & neck squamous cell carcinomas

Molecular Oncology, EarlyView.
This study identifies somatostatin receptor 4 (Sstr4) as a critical tumor suppressor against skin and head/neck cancers (HNSCC, cSCC, and BCC). The loss of Sstr4 removes a check on cell growth, causing hyperactivation of the MAPK‐ERK signaling pathway (↑).
Ali Taqvi, Tuan Khang Huynh, Adway Kadam, Zahra Kardan, Yue Yan, Amina Jamal Laham, Sampath Kumar Loganathan   +6 more
wiley   +1 more source

Can people afford to pay for health care? New evidence on financial protection in Malta: summary

6 p.This review assesses the extent to which people in Malta face financial barriers that prevent them from accessing health care or experience financial hardship when they use health care. It covers the period from 2008 to 2025 using data from household
World Health Organization. Regional Office for Europe
core  

Gender and other diversity-related factors in psychiatric hospital care: protocol for the participatory mixed-methods PSY-DIVER study. [PDF]

BMC Psychiatry
Peters SJ, Kratzke S, Ahmed M, Staninska A, Aliu A, Flaspöler MF, Zielasek J, Schuster C, Gouzoulis-Mayfrank E.   +8 more
europepmc   +1 more source

Castration‐resistant prostate cancer cells are addicted to the high activity of cyclin‐dependent kinase 2

Molecular Oncology, EarlyView.
We show that emergence of castration‐resistant prostate (CRPC) is associated with significant upregulation of cyclins that positively regulate cyclin‐dependent kinase 2 (CDK2) and concomitant downregulation of CDK4 cyclins. This renders CRPC cells dependent on the high activity of CDK2, and CDK2 inhibitors synergistically sensitize CRPC cells to both ...
Joyeeta Chatterjee, Alessia Marin, Shivani Yalala, Harri M. Itkonen   +3 more
wiley   +1 more source

Partial FAK suppression promotes tumor growth, an effect reversed by macrophage p110δ PI3K inactivation

Molecular Oncology, EarlyView.
Partial inhibition of focal adhesion kinase (FAK) can paradoxically promote tumor growth, rather than simply producing a weaker antitumor effect than that observed with strong FAK suppression. In breast cancer and melanoma models, targeting p110δ PI3K, particularly in macrophages, counteracted these tumor‐promoting effects, highlighting the importance ...
Lydia Xenou, Niki Tzenaki, Anna Tsapara, Maria Tzardi, Evangelia A. Papakonstanti   +4 more
wiley   +1 more source

Can people afford to pay for health care? New evidence on financial protection in Italy: summary

6 p.This review assesses the extent to which people in Italy face financial barriers to access or experience financial hardship when they use health care.
World Health Organization. Regional Office for Europe
core  

Bereavement care practices: A national survey of Australian paediatric intensive care units. [PDF]

Crit Care Resusc
Jolly AN, Gibbons KS, Butler AE, Erickson S, Davies K, Masterson K, Sharbanee JM, Gill FJ, ANZICS Paediatric Study Group.   +8 more
europepmc   +1 more source