Results 201 to 210 of about 15,275,318 (300)

Single‐molecule DNA flow‐stretch assays for high‐throughput DNA–protein interaction studies

FEBS Open Bio, EarlyView.
We describe an optimised single‐molecule DNA flow‐stretch assay that visualises DNA–protein interactions in real time. Linear DNA fragments are tethered to a surface and stretched by buffer flow for fluorescence imaging. Using λ and φX174 DNA, this protocol enhances reproducibility and accessibility, providing a versatile approach for studying diverse ...
Ayush Kumar Ganguli, Mohammad Nour Alsamsam, Ugnė Bagdonaitė, Van Truc Vu, Chun‐Jen Huang, Polina Kuzhir, Mindaugas Zaremba, Aurimas Kopūstas, Marijonas Tutkus   +8 more
wiley   +1 more source

Global challenges and perspectives in acute and emergency general surgery in low and middle-income countries: a scoping review. [PDF]

BMJ Glob Health
Hindawi MD, Isik A, Rosa F, Visconti D, Nechay T, Chowdhury S, Ndong A, Mishra TS, Cioffi SPB, Kalmoush AE, Piscioneri F, Biffl WL, Tan ECTH.   +12 more
europepmc   +1 more source

UiO‐66 metal–organic frameworks in biomedicine: From structural tunability to bioimaging, photodiagnostics, and photodynamic cancer therapy

FEBS Open Bio, EarlyView.
UiO‐66(Zr) metal–organic frameworks are chemically stable, biocompatible, and highly tunable nanomaterials. Their modular structure enables controlled drug delivery, multimodal bioimaging, and light‐activated photodynamic therapy, supporting integrated diagnostic and therapeutic (theranostic) applications in cancer and biomedical research.
Veronika Huntošová, Grigorii Rakhalskii, Miroslav Almáši   +2 more
wiley   +1 more source

Access to malaria diagnosis and treatment in Zambia in the context of scaling-up community case management: Results from repeated national cross-sectional surveys. [PDF]

PLOS Glob Public Health
Mao Z, Bennett A, Silumbe K, Miller J, Millar J, Slater H, Yukich J, Ashton RA, Kyomuhangi I, Andrada A, Karabo R, Eisele TP.   +11 more
europepmc   +1 more source

Aquaporin‐3 and aquaporin‐5 impact the development of pancreatic ductal adenocarcinoma spheroids

FEBS Open Bio, EarlyView.
Schematic representation of the role of aquaporin‐3 (AQP3) and aquaporin‐5 (AQP5) in pancreatic ductal adenocarcinoma (PDAC). Both proteins are upregulated in PDAC and are associated with tumor progression and metastatic potential. Silencing AQP3 or AQP5 in PDAC spheroids results in decreased diameter, area, and overall growth, underscoring their key ...
Catarina Pimpão, Diogo M. Engrácia, Graça Soveral, Filipa Mendes   +3 more
wiley   +1 more source

Development of Guidelines for Implementing Digital Technology Into In-Home Aged Care: Mixed Methods Approach. [PDF]

JMIR Form Res
Batchelor F, Williams S, Hwang K, Kwan BPM, Dickins M, Walsh T, Jakupovic H, Lock K, Davison TE.   +8 more
europepmc   +1 more source

Hyperactive ice‐binding proteins stabilize cell membranes and improve resistance to dehydration stress in Caenorhabditis elegans

FEBS Open Bio, EarlyView.
TisIBP8, a fungal‐derived hyperactive ice‐binding protein, helps Caenorhabditis elegans survive dehydration. It localizes near cell membranes, reduces cell damage, and helps maintain membrane structure during drying. These results suggest that ice‐binding proteins can protect cells from dehydration stress as well as freezing stress.
Daiki Shimose, Kotaro Ozaki, Ryohei Kuriyama, Yuka Ikemoto, Kazuhiro Mio, Yuji C. Sasaki, Tatsuya Arai, Sakae Tsuda, Yoichi Shinkai, Masahiro Kuramochi   +9 more
wiley   +1 more source

Neonatal Unit Colonization Pressure and Acquisition of Extended-Spectrum β-Lactamase Gut Colonization.

JAMA Netw Open
Cook A, Berkell M, van Werkhoven CH, Sieswerda E, Smith DRM, Minotti C, van Heirstraeten L, Iosifidis E, Roilides E, Metsvaht T, Pijoan Zubizarreta JI, Loureiro-Gonzalez B, Giannoni E, Messina C, Malhotra-Kumar S, Bielicki JA, NeoIPC Feasibility Group, Martin J, Djukic F, Tapia-Collados C, García-Cantó E, Gkentzi D, Papachatzi E, Dimopoulou V, Roehr CC, Brock P, Hatzidaki E, Anagnostatou NH, Baraldi E, Priante E, Sarafidis K, Kontou A, Mitsiakos G, Gialamprinou D, Papaevangelou V, Livieratou M, Tanney K, Booth N, Tolentino D, Reid A, Ftergioti A, Simitsopoulou M, Tataropoulou K, Koemtzidou E, de Alba Romero C, Sendin EB, Perez-Lopez J, Campos-Franco Y, Pietrzyk A, Haube G, Ilmoja ML, Padari H, Stocker M, Périsset A, Gruszfeld D, Clarke P, Myhill J, Cabañas F, Giuffrè M, Notarbartolo V, Wellmann S, Badura A.   +61 more
europepmc   +1 more source

Big data and psychiatry: advances, constraints and future directions. [PDF]

World Psychiatry
Stein DJ, Kessler RC, Torous J, Garavan H, van den Heuvel OA, Derks EM, Mathews C, Cuijpers P, Salum GA, Andreassen OA, Thompson PM, Penninx BWJ, McGrath JJ.   +12 more
europepmc   +1 more source