Results 111 to 120 of about 493,555 (263)

How Health Care Workers Can Manage Digital Fatigue. [PDF]

J Med Internet Res
Novak S.
europepmc   +1 more source

Reconstructing enzyme evolution by protein engineering

FEBS Letters, EarlyView.
Natural enzyme evolution can be retraced by protein engineering methods such as directed evolution, rational design, and ancestral sequence reconstruction. These approaches reveal how enzymes emerged from ligand‐binding scaffolds, developed varying substrate preferences, formed oligomeric complexes, adapted to environmental changes, and evolved novel ...
Lukas Drexler, Markus R. Busch, Reinhard Sterner   +2 more
wiley   +1 more source

Persistence and booster response of rabies antibodies among health care workers with multiple vaccinations. [PDF]

Trop Med Health
Castellano MJ, Sornillo JB, Saito N, Nishizono A, Demetria C, Nacion L, Quiambao B.   +6 more
europepmc   +1 more source

Microbiome‐blood–brain barrier interactions in aging — mechanisms and therapeutic potential

FEBS Letters, EarlyView.
Aging reshapes the gut microbiome (↓SCFA‐producing commensals; ↑pro‐inflammatory outputs), shifting circulating metabolites (↓SCFAs; ↑LPS, ↑TMAO, ↑PAA) that act at the BBB to increase nonspecific transcytosis, alter transport, and promote astrocyte reactivity, heightening brain vulnerability.
Daniel Cuervo‐Zanatta, Hari Baskar Balasubramanian, Amir Pasokh, Marietta Zille   +3 more
wiley   +1 more source

Level of health care and services in a tertiary health setting in Nigeria

Nigerian Journal of Paediatrics
Background: There is a growing awareness and demand for quality health care across the world; hence the need to describe the level of health care and services provided to meet the patient centered care by the frontline stakeholders.
Ahmed PA , Sibbel R, Jones C
doaj  

Measles serostatus among health care workers in a university clinic in Hungary in 2024. [PDF]

Prev Med Rep
Timmer B, Balázs B, Boros Á, Tibold A, Sebestyén A, Reuter G.   +5 more
europepmc   +1 more source

Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment

Molecular Oncology, EarlyView.
This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
wiley   +1 more source

Precarious work and Covid-19: repercussions on the health of primary health care workers. [PDF]

Rev Saude Publica
Mendonça TT, Barros SG, Rossi TRA, Carvalho ACR, Cruz DN, Magno L, Dourado I.   +6 more
europepmc   +1 more source

Circular RNA expression landscapes in myelodysplastic neoplasms: Associations with mutational signatures and disease progression

Molecular Oncology, EarlyView.
In this explorative study, the abundance of circular RNA molecules in bone marrow stem cells was found to be elevated in patients with high‐risk myelodysplastic neoplasms, and to be associated with an increased risk of progression to acute myeloid leukemia.
Eileen Wedge, Morten Tulstrup, Gabriele Todisco, Pedro Moura, Christophe Côme, Jakob Werner Hansen, Jakob Schmidt Jespersen, Balthasar Schlotmann, Maria Creignou, Mette Dahl, Claudia Schöllkopf, Klas Raaschou‐Jensen, Krister Wennerberg, Bo Porse, Joachim Weischenfeldt, Eva Hellström‐Lindberg, Lasse Sommer Kristensen, Kirsten Grønbæk   +17 more
wiley   +1 more source

Moral distress of primary health care workers during the global pandemic. [PDF]

Sci Rep
Doğan M, Akpınar A.
europepmc   +1 more source