Results 151 to 160 of about 496,967 (263)

Infection prevention and control measures for Ebola disease and their outcomes from the perspective of health care workers: a mixed-methods study. [PDF]

BMC Public Health
Honein-AbouHaidar G, Khabsa J, Willet V, Dixit D, Hoteit R, Mearns S, Baller A, Akl E.   +7 more
europepmc   +1 more source

Epigenetic silencing of the liver‐specific lncRNA LUNAR promotes liver cancer progression via NOTCH activation

Molecular Oncology, EarlyView.
LUNAR is a liver‐specific long noncoding RNA (lncRNA) that is highly expressed in normal liver but becomes epigenetically silenced in hepatocellular carcinoma through promoter hypermethylation. Loss of LUNAR is associated with NOTCH activation, epithelial–mesenchymal transition, and metastasis, whereas restoring LUNAR restrains metastatic progression ...
Se Ha Jang, Hyung Seok Kim, Geum Ok Baek, Moon Gyeong Yoon, Su In Lee, Jee‐Yeong Jeong, Ji Eun Han, Soon Sun Kim, Jae Youn Cheong, Jung Woo Eun   +9 more
wiley   +1 more source

Impact of Cardiopulmonary Resuscitation Health Care Workers' Physical Health Parameters on Cardiopulmonary Resuscitation Performance Quality in Simulated Manikin-Based Settings-A Systematic Review. [PDF]

J Am Coll Emerg Physicians Open
Prakash P, Nayak KR, Babu AS, Devi ES, Chaudhuri S, Pai DR, Krishnan S V.   +6 more
europepmc   +1 more source

Single‐cell DNA methylation profiling: Technologies, computation, and applications in precision oncology

Molecular Oncology, EarlyView.
Single‐cell DNA methylation (scDNAme) profiling maps epimutational clonal evolution, revealing mechanisms of malignancy and therapeutic resistance across diverse cancer types. By providing a high‐resolution landscape of intratumoral heterogeneity, these technologies empower precise patient stratification, guide the development of enhanced ...
Ik Soo Kim
wiley   +1 more source

Interferon beta drives therapy resistance in a patient‐derived model of high‐grade serous ovarian cancer

Molecular Oncology, EarlyView.
Interferon type 1 (IFN‐1) production and signaling is associated with the acquisition of therapy resistance, following chronic DNA damage, via Interferon‐related DNA damage resistance signature (IRDS) gene expression. An alternative, DNA damage‐independent role of sustained IFN‐1 mediated resistance was identified and characterized by the emergence of ...
Ashlyn Conant, Tise Suzuki, Kiera McGivney, V. S. S. Abhinav Ayyadevara, Sharon Asariah, Jay Deng, Ethan Nyein, Jacqueline Coats, Gary Yu, Yevgeniya J. Ioffe, Christian Hurtz, Juli J. Unternaehrer   +11 more
wiley   +1 more source

Organizational Readiness for Change in the Era of Smart Hospital Wards: Qualitative Study of Health Care Workers' Insights. [PDF]

JMIR Hum Factors
Lim HW, Sumner J, Ang A, Keck C, Chew EHH, Yip AW.   +5 more
europepmc   +1 more source

PANoptosis in the pathogenesis of myelodysplastic syndromes

Molecular Oncology, EarlyView.
PANoptosis, a combination of three types of programmed cell death, is mediated by a large protein complex called a PANoptosome. In healthy bone marrow hematopoietic cells, PANoptosis is restricted by inhibitory signaling. In MDS, bone marrow cells become sensitive to the PANoptotic stimuli due to the aberrant inactivation of inhibitory signaling or ...
Rohit Thalla, Jyoti Lamichhane, Cameron Lewis, Peter Breslin, Jiwang Zhang   +4 more
wiley   +1 more source

The Effects of Indoor Pollutants on Health Care Workers, Patients, and Caregivers in Dental Clinics: A Systematic Review. [PDF]

Eur J Dent
Tetè G, Santilli M, Vinskid NC, Profili F, Tafuri G, D'Addazio G, Sinjari B.   +6 more
europepmc   +1 more source

Spatial biology in cancer epigenetics

Molecular Oncology, EarlyView.
Spatial epigenomics combines molecular profiling with tissue architecture to reveal how gene regulation is organized within intact tissues. In cancer, these technologies uncover the mechanisms driving tumor heterogeneity and microenvironmental interactions, opening new opportunities for biomarker discovery and precision medicine.
Eva Crespo‐García, Manel Esteller
wiley   +1 more source

COVID-19 vaccination status and motivators among Canadian health care workers: are they different from the general population? [PDF]

J Occup Health
Léger C, Gosselin Boucher V, Deslauriers F, Gupta S, Dialufuma MV, Vallis M, Bacon SL, Lavoie KL.   +7 more
europepmc   +1 more source