Results 71 to 80 of about 572,971 (310)

Tau acetylation at K331 has limited impact on tau pathology in vivo

FEBS Letters, EarlyView.
We mapped tau post‐translational modifications in humanized MAPT knock‐in mice and in amyloid‐bearing double knock‐in mice. Acetylation within the repeat domain, particularly around K331, showed modest increases under amyloid pathology. To test functional relevance, we generated MAPTK331Q knock‐in mice.
Shoko Hashimoto, Yukio Matsuba, Mika Takahashi, Takaomi C. Saido   +3 more
wiley   +1 more source

Effectiveness of oral health education among primary health care workers at the primary health center in Nellore district, Andhra Pradesh

Journal of Indian Association of Public Health Dentistry, 2014
Background: Primary dental care can be a way of achieving good oral health for the community. This can be achieved by integration of oral health care with the existing primary health care activities through training of primary health care workers on ...
Muthyala Pavana Sandhya, M Shanthi, Nusrath Fareed, K M Sudhir, R.V.S Krishna Kumar   +4 more
doaj   +1 more source

Gut microbiome and aging—A dynamic interplay of microbes, metabolites, and the immune system

FEBS Letters, EarlyView.
Age‐dependent shifts in microbial communities engender shifts in microbial metabolite profiles. These in turn drive shifts in barrier surface permeability of the gut and brain and induce immune activation. When paired with preexisting age‐related chronic inflammation this increases the risk of neuroinflammation and neurodegenerative diseases.
Aaron Mehl, Eran Blacher
wiley   +1 more source

Community health workers in Sergipe, Brazil : Implications for their future role in maternal and child health [PDF]

Every year six million children die worldwide due to diseases that are easily preventable or curable. Interventions to reduce the number of deaths are offered by health facilities, yet many children continue to die at home without receiving any type of ...
Cesar, Juraci A
core   +1 more source

Workers’ health care network, accidents at work, and prevalent occupational diseases in the municipality of Campos dos Goytacazes

Vértices, 2016
The purpose of this paper is to analyze the workers’ health care in the Unified Health System (SUS), in the municipality of Campos dos Goytacazes, from the creation of the Network for Integral Worker Health Care - RENAST in 2002 to 2012.
Rosélia Périssé da Silva Piquet, Elizabeth da Silva Gama, Elis de Araújo Miranda   +2 more
doaj   +1 more source

Tuberculosis in health care workers in Belarus [PDF]

Public Health Action, 2014
Setting: Tuberculosis (TB), including drug-resistant TB, is a serious problem in Belarus. Objectives: To determine the prevalence of TB among health care workers (HCWs) along with patient characteristics, treatment outcomes and drug resistance patterns between 2008 and ...
Klimuk, D, Hurevich, H, Harries, AD, Babrukevich, A, Kremer, K, Van den Bergh, R, Acosta, CD, Astrauko, A, Skrahina, A   +8 more
openaire   +3 more sources

The ubiquitin ligase RNF115 is required for the clearance of damaged lysosomes

FEBS Letters, EarlyView.
Upon lysosomal rupture, an E3 ubiquitin ligase RNF115 translocates from the cytosol to the damaged lysosomal membrane. Moreover, RNF115 depletion impairs the clearance of damaged lysosomes, identifying it as a key regulator of lysosomal quality control.
Sae Nakanaga, Toshiki Takahashi, Akiko Kuma, Hiroyuki Kawahara   +3 more
wiley   +1 more source

Organizing the interface—Plasma membrane architecture and receptor dynamics in virus‐cell interactions

FEBS Letters, EarlyView.
Plasma membranes contain dynamic nanoscale domains that organize lipids and receptors. Because viruses operate at similar scales, this architecture shapes early infection steps, including attachment, receptor engagement, and entry. Using influenza A virus and HIV‐1 as examples, we highlight how receptor nanoclusters, multivalent glycan interactions ...
Jan Schlegel, Christian Sieben
wiley   +1 more source

Removing financial barriers to access reproductive, maternal and newborn health services: the challenges and policy implications for human resources for health. [PDF]

, 2013
The last decade has seen widespread retreat from user fees with the intention to reduce financial constraints to users in accessing health care and in particular improving access to reproductive, maternal and newborn health services.
Barbara McPake, Witter, S, Ensor, Tim, Sophie Witter, David Newlands, Newlands, D., Chirwa, Yotamu, Suzanne Fustukian, Yotamu Chirwa, Martineau, Tim, Tim Martineau, Newlands, D, Tim Ensor, McPake, Barbara, McPake, B, Martineau, Timothy, Fustukian, S, Witter, Sophie, Martineau, T, Chirwa, Y, Newlands, David, Ensor, T, Fustukian, Suzanne   +22 more
core   +1 more source

Risk of AIDS to health care workers. [PDF]

BMJ, 1986
This article reviews evidence on the risk of acquired immunodeficiency syndrome (AIDS) to health workers and suggests guidelines for the clinical care of AIDS patients. No health worker in the world has yet contracted AIDS from a patient. However seroconversion to human T-lymphotropic virus type III (HTLV-III) has occurred in a small number.
openaire   +2 more sources