Results 171 to 180 of about 2,002,433 (288)

Looking to the Future: Prospective Life Cycle Assessment of Emerging Technologies

open access: yesChemistry – A European Journal, EarlyView.
This review explores prospective life cycle assessment (pLCA), an emerging methodology for evaluating the environmental impacts of technologies still in development. Key aspects are identified, including assessing technology maturity levels, upscaling methods, and generating future scenarios.
Alessandro Marson   +2 more
wiley   +1 more source

Need for a Strong FOPL in India-position Statement. [PDF]

open access: yesIndian J Community Med
Sharma N   +7 more
europepmc   +1 more source

Impact of Regulatory Post‐Market Safety Advisories on Prescribing Practices: An Interrupted Time Series Analysis

open access: yesClinical Pharmacology &Therapeutics, EarlyView.
Less frequent adverse drug reactions are usually discovered after a drug's release to the market, making effective and timely communication of regulatory post‐market advisories essential for preventing emerging adverse effects. Time series analysis is a key study design for assessing the impact of post‐market safety advisories.
Seonji Kim   +6 more
wiley   +1 more source

A Benchmark, Expand, and Calibration (BenchExCal) Trial Emulation Approach for Using Real‐World Evidence to Support Indication Expansions: Design and Process for a Planned Empirical Evaluation

open access: yesClinical Pharmacology &Therapeutics, EarlyView.
Real‐world evidence involving healthcare database studies is well established for making causal inferences in post‐market drug safety studies and methods, data, and research infrastructure for evaluating effectiveness have advanced in recent years. The rapidly expanding field of etiologic research using insurance claims and electronic health records ...
Shirley V. Wang   +6 more
wiley   +1 more source

Assessment of front and back of pack nutrition labels of selected convenience food products and snacks available in the Indian market. [PDF]

open access: yesPLoS One
Shobana S   +9 more
europepmc   +1 more source

Impact of Model‐Informed Drug Development on Drug Development Cycle Times and Clinical Trial Cost

open access: yesClinical Pharmacology &Therapeutics, EarlyView.
Model‐informed drug development (MIDD) integrates data to quantify benefit/risk informing objective drug discovery and development decisions. An additional critical benefit of MIDD is postulated to be improvement in trial and program efficiencies. While the application of MIDD has grown, there have been no clear examples across programs to demonstrate ...
Vaishali Sahasrabudhe   +4 more
wiley   +1 more source

Use of Real‐World Claims Data to Assess the Prevalence of Concomitant Medications to Inform Drug–Drug Interaction Risk in Target Patient Populations

open access: yesClinical Pharmacology &Therapeutics, EarlyView.
A common issue in clinical drug development involves drug–drug interactions (DDI) that may lead to altered drug exposure and subsequent altered safety and efficacy of an investigational drug or concomitant medications (conmeds) in the target patient population.
Alice S. Tang   +6 more
wiley   +1 more source

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