Results 81 to 90 of about 3,903,440 (355)

Patient‐specific pharmacogenomics demonstrates xCT as predictive therapeutic target in colon cancer with possible implications in tumor connectivity

open access: yesMolecular Oncology, EarlyView.
This study integrates transcriptomic profiling of matched tumor and healthy tissues from 32 colorectal cancer patients with functional validation in patient‐derived organoids, revealing dysregulated metabolic programs driven by overexpressed xCT (SLC7A11) and SLC3A2, identifying an oncogenic cystine/glutamate transporter signature linked to ...
Marco Strecker   +16 more
wiley   +1 more source

Exploring variation in parental worries about HPV vaccination: a latent-class analysis

open access: yesHuman Vaccines & Immunotherapeutics, 2019
Background. Prior research has identified diverse worries that parents have about HPV vaccination. We sought to understand how parents prioritize worries and to identify subgroups of parents according to shared patterns of worry. Methods.
Melissa B. Gilkey   +5 more
doaj   +1 more source

The Virtual Health Sciences Library of the Balearic Islands: A regional project for libraries cooperation. [PDF]

open access: yes, 2010
Virtual Health Sciences Library of the Balearic Islands (Bibliosalut) is a regional project carried out in collaboration with the Regional Ministry of Health and Consumer Protection and the Health Service of the Balearic Islands (Ib-salut), through the ...
Costa-Marín, Maria   +4 more
core  

Aggressive prostate cancer is associated with pericyte dysfunction

open access: yesMolecular Oncology, EarlyView.
Tumor‐produced TGF‐β drives pericyte dysfunction in prostate cancer. This dysfunction is characterized by downregulation of some canonical pericyte markers (i.e., DES, CSPG4, and ACTA2) while maintaining the expression of others (i.e., PDGFRB, NOTCH3, and RGS5).
Anabel Martinez‐Romero   +11 more
wiley   +1 more source

The Role of Patient and Physician in Establishing Patient-Physician Communication in the In-Patient Environment [PDF]

open access: yes, 2016
Communication in the in-patient environment is crucial, and the relationship between a patient and physician can enhance patient health and improve overall wellness.
Sahni, Tamanna
core   +1 more source

Survivin and Aurora Kinase A control cell fate decisions during mitosis

open access: yesMolecular Oncology, EarlyView.
Aurora A interacts with survivin during mitosis and regulates its centromeric role. Loss of Aurora A activity mislocalises survivin, the CPC and BubR1, leading to disruption of the spindle checkpoint and triggering premature mitotic exit, which we refer to as ‘mitotic slippage’.
Hana Abdelkabir   +2 more
wiley   +1 more source

The Effectiveness of Online Messages for Promoting Smoking Cessation Resources: Predicting Nationwide Campaign Effects From Neural Responses in the EX Campaign

open access: yesFrontiers in Human Neuroscience, 2020
What are the key ingredients that make some persuasive messages resonate with audiences and elicit action, while others fail? Billions of dollars per year are put towards changing human behavior, but it is difficult to know which messages will be the ...
Ralf Schmälzle   +13 more
doaj   +1 more source

Introduction to the current EU regulation on health claims, with special reference to berries [PDF]

open access: yes, 2007
In the regulation claims are divided into two main categories: nutrition and health claims. In the future only claims that are positively pre-evaluated by EFSA are allowed to be used in commercial communication (all means).
Sarkkinen, Essi
core  

Liquid biopsy epigenetics: establishing a molecular profile based on cell‐free DNA

open access: yesMolecular Oncology, EarlyView.
Cell‐free DNA (cfDNA) fragments in plasma from cancer patients carry epigenetic signatures reflecting their cells of origin. These epigenetic features include DNA methylation, nucleosome modifications, and variations in fragmentation. This review describes the biological properties of each feature and explores optimal strategies for harnessing cfDNA ...
Christoffer Trier Maansson   +2 more
wiley   +1 more source

Participant and caregiver perspectives on health feedback from a healthy lifestyle check

open access: yesHealth Expectations
Introduction The usual output following health consultations from paediatric services is a clinical letter to the referring professional or primary care provider, with a copy sent to the patient's caregiver.
Miranda D. Lee   +6 more
doaj   +1 more source

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