Results 81 to 90 of about 8,386,406 (288)

Conhecimento dos usuários, trabalhadores da saúde e gestores sobre conselheiros e Conselhos de Saúde

Saúde em Debate
A criação de um espaço democrático de participação na condução do Sistema Único de Saúde (SUS) constituiu indubitável conquista dos brasileiros. O pleno exercício deste direito implica, no entanto, no conhecimento do próprio direito, dos espaços e dos ...
Camila Sartori Martins, Michele Thaís Sartori, Helena Luiza Douat Dietrich, Fabiane Barbero Klem, Camilo Dallagnol, Guilherme Souza Cavalcanti de Albuquerque, Paulo de Oliveira Perna, Samya Mehanna   +7 more
doaj  

Finding novel vulnerabilities of hypomorphic BRCA1 alleles

Molecular Oncology, EarlyView.
Synthetic lethality screens performed to identify novel vulnerabilities often model complete gene loss, thereby overlooking patient‐derived hypomorphic mutations. In this study, we have performed genome‐wide CRISPR screens on BRCA1 hypomorphic mutations, showing BRCA1I26A behaves like wild‐type, while BRCA1R1699Q mimics deficiency. Furthermore, we have
Anne Schreuder, Klaas de Lint, Hồ Mỹ Phúc Võ, Mariana M. Góis, Rosalie A. Kampen, Marta San Martin Alonso, Ilse Nootenboom, Veronica Garzero, Tiemen J. Wendel, Rob M. F. Wolthuis, Sylvie M. Noordermeer   +10 more
wiley   +1 more source

A participação da sociedade civil na democratização do setor de saúde no Brasil

Revista Brasileira de Educação Médica
Este ensaio apresenta a trajetória da participação da sociedade civil brasileira nas conquistas do setor de saúde no período da redemocratização política no País.
Claudio Valdivino e Silva, Diego Ferreira Lima Silva, Elza Maria de Souza   +2 more
doaj  

CONSTRUCTION OF SOCIAL CONTROL IN THE MUNICIPALITY OF FAIR SANTANA - BAHIA: THE DECENTRALIZATION PROCESS [PDF]

Revista Gestão & Saúde, 2014
The recognition of Brazil as a citizen tends to open spaces for democratic construction, so that with this organizing principle of society shall participate effectively in state actions.
Paulo Roberto Lima Falcão do Vale, Ozemária da Silva Oliveira, Waldson Nunes de Jesus, Adroaldo dos Santos, Maricélia Maia de Lima   +4 more
doaj  

Oncogenic DMTF1β promotes cancer cell motility by regulating autophagy through ULK1 stabilization

Molecular Oncology, EarlyView.
In the current study, we demonstrate that the oncogene DMTF1β regulates ULK1 stability by reducing its proteasomal degradation in cancer cells. This stabilization enables ULK1 to induce autophagy, which in turn facilitates cancer cell migration. Consequently, reduced DMTF1β levels lead to decreased autophagy and impaired cancer cell migration.
Jun Xu, Nicolas J. Niklaus, Anna M. Schläfli, Igor Tokarchuk, Magali Humbert, Federico La Manna, Bich Vu, David Maul, Ramin Radpour, Marianna Kruithof‐de Julio, Inti Zlobec, Jörn Dengjel, Bruce E. Torbett, Mario P. Tschan   +13 more
wiley   +1 more source

Changes in the proportion of facility-based deliveries and related maternal health services among the poor in rural Jhang, Pakistan: results from a demand-side financing intervention

International Journal for Equity in Health, 2011
Background Demand-side financing projects are now being implemented in many developing countries, yet evidence showing that they reach the poor is scanty.
Agha Sohail
doaj   +1 more source

Liquid biopsy‐based diagnostic evaluation of hypermethylated CpG sites for ovarian cancer diagnosis

Molecular Oncology, EarlyView.
This schematic outlines the workflow from biomarker identification to duplex MethyLight assay validation for epithelial ovarian cancer diagnosis using cfDNA‐based liquid biopsy. Initial screening of hypermethylated CpG candidates (cg02957270, cg10061138 cg00480298, COL2A1) was performed in tissue using ARMS‐PCR, COBRA, qPCR and image analysis. Selected
Deepa Bisht, Sameer Gupta, Amrita Chaurasia, Manisha Sachan   +3 more
wiley   +1 more source

Social determinants of health and local government: understanding and uptake of ideas in two Australian states

Australian and New Zealand Journal of Public Health, 2017
Objective: To examine the awareness and perceptions of local government staff about the social determinants of health (SDoH) and health inequity and use of these ideas to shape policy and practice.
Angela Lawless, Anna Lane, Felicity‐ann Lewis, Fran Baum, Patrick Harris   +4 more
doaj   +1 more source

CONTROLE SOCIAL E CONSELHOS LOCAIS DE SAÚDE EM TERESINA: LIMITES E POSSIBILIDADES SOCIAL CONTROL AND LOCAL COUNCILS OF HEALTH TERESINA: LIMITS AND POSSIBILITIES

, 2013
Este artigo e fruto de pesquisa que analisa o controle social nos Conselhos Locais de Saude de Teresina. Tem o objetivo de apresentar a analise da atuacao dos Conselhos Locais de Saude em Teresina (PI), no periodo 2010 a 2011, observando quais os limites
J. Miranda, Simone de Jesus Guimarães
semanticscholar   +1 more source

Automated FRAP microscopy for high‐throughput analysis of protein dynamics in chromatin organization and transcription

FEBS Open Bio, EarlyView.
RoboMic is an automated confocal microscopy pipeline for high‐throughput functional imaging in living cells. Demonstrated with fluorescence recovery after photobleaching (FRAP), it integrates AI‐driven nuclear segmentation, ROI selection, bleaching, and analysis.
Selçuk Yavuz, Bart Geverts, Johan A. Slotman, Andrea Sacchetti, Stefan Prekovic, Martin E. van Royen, Adriaan B. Houtsmuller   +6 more
wiley   +1 more source