Results 141 to 150 of about 41,358,503 (314)
Degradation mechanism of the von Willebrand factor A2 domain by nattokinase
FEBS Letters, EarlyView.Nattokinase, a natto‐derived protease, exhibits potent antithrombotic effects. This study demonstrates that nattokinase directly cleaves the von Willebrand factor (vWF) A2 domain in vitro. Unlike the native regulator ADAMTS13, nattokinase degrades folded vWF independently of shear stress.
Ryuichi Hyakumoto +3 more
wiley +1 more source
International Journal of Population Data ScienceBackground In healthcare research, leveraging data is vital for driving advancements in treatment, diagnosis, and healthcare delivery. However, transparency in data use is pivotal for credible, reproducible findings.
Emma-Jane Loveridge +5 more
doaj +1 more source
Health Data Set Bias Examination in the European Health Data Space
Diversity in health datasets is a necessary, quantifiable property of inclusivity across key domains (e.g., demographic, socioeconomic, health, and environmental) that directly shapes how well research generalizes and how fair its impacts are. In its absence, interventions risk encoding bias and exacerbating health disparities. In this work, we outline
Markatou, Evangelia Anna +1 more
openaire +2 more sources
FEBS Letters, EarlyView.We present robust protocols for the preparation of supported lipid bilayers (SLBs) incorporating either Salmonella smooth LPS or outer membrane vesicles (OMVs). We use a combination of quartz crystal microbalance with dissipation (QCM‐D) and fluorescence microscopy to both characterize the SLBs of various compositions and to probe their interactions ...
Hudson P. Pace +6 more
wiley +1 more source
From mice to humans—divergent strategies for intestinal homeostasis and regeneration
FEBS Letters, EarlyView.Recent advances such as organoid genome editing, xenotransplantation, imaging, and whole‐genome sequencing have enabled direct studies of human intestinal stem cells (ISCs). These studies reveal species‐specific features, including slower ISC proliferation, distinct injury responses, slower somatic mutation accumulation in humans, and an inverse ...
Keiko Ishikawa +2 more
wiley +1 more source
Design and analysis strategies for robust microbiome ageing research
FEBS Letters, EarlyView.The gut microbiome changes with age and associates with age‐related morbidity and mortality, establishing it as a potential biomarker and intervention target for ageing. Realising this potential requires methodological rigour, yet distinguishing biological signals from methodological artefacts remains challenging across cohorts. This review provides an
Mark Olenik +5 more
wiley +1 more source
NT Aboriginal Health Key Performance Indicators - Definitions
, 2018 The Northern Territory Aboriginal Health Key Performance Indicator Information System (NT AHKPI) provides information on and collaboration between both government and non-government health services for reporting key performance indicator (KPI) data on ...
Department of Health
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Management Data Report November 2017 [PDF]
, 2018 The HSE's Performance Assurance Report (PAR) provides an overall analysis of key performance data from Divisions, such as Acute, Mental Health, Social Care, Primary Care, Health and Wellbeing as well as Finance and HR. The activity data reported is based
Health Service Executive (HSE)
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FEBS Letters, EarlyView.CT10 regulator of kinase (CRK) and CRK‐Like (CRKL) are signaling adaptors driving cell adhesion, motility, differentiation, and proliferation. SH2‐domain containing (SH) proteins are enriched in YXXP motifs which when phosphorylated create preferred binding sites for CRK family SH2 domains.
Phoebe M. Cousens +8 more
wiley +1 more source
Maryland Chartbook of Minority Health And Minority Health Disparities Data [PDF]
, 2009 The Office of Minority Health and Health Disparities (MHHD) was established in the Maryland Department of Health and Mental Hygiene in 2004 by legislation passed in the Maryland General Assembly session of that same year.
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