Results 121 to 130 of about 436,608 (301)

Oral health literacy and dental anxiety: A study among dental patients in Malaysia

open access: yesЭндодонтия Today
AIM. The study’s objective was to assess the levels of oral health literacy (OHL) and dental anxiety (DA) among patients and to examine any potential correlation between OHL and DA.MATERIALS AND METHODS.
J. Pillay   +7 more
doaj   +1 more source

Extracellular Vesicle‐Delivered tRF‐His‐GTG‐1 Reprograms Neutrophil Lipophagy and Triggers Inflammation in COVID‐19

open access: yesAdvanced Science, EarlyView.
This study identifies platelet‐derived extracellular vesicles as key immunometabolic regulators in COVID‐19. The delivery of tRF‐His‐GTG‐1 to neutrophils activates TLR8mTOR signaling, disrupts lipophagy, and amplifies NET‐mediated inflammation. Importantly, targeting this axis restores neutrophil homeostasis, offering a potential therapeutic strategy ...
Tsai‐Ling Liao   +5 more
wiley   +1 more source

Trends in Child Health 1997-2006: Assessing Black-White Disparities [PDF]

open access: yes, 2009
Analyzes disparities in health indicators of African-American and white children, including low birthweight, unmet dental care needs, asthma, and learning disabilities.
Anna L. Wheatley, Wilhelmina A. Leigh
core  

Treatment with Minicircle DNA Expressing a FGF23 Fragment in a Clinically relevant Mouse Model of X‐Linked Hypophosphatemic Rickets

open access: yesAdvanced Science, EarlyView.
The pathogenic role of PHEX isn't fully determined, and there is no radical cure for X‐linked hypophosphatemic rickets (XLHR). This study makes the first attempt to perform gene therapy using a minicircle DNA (MC‐DNA) vector expressing a fragment of FGF23 (amino acids 180‐251) in Phex‐T1349C mice and suggests MC‐DNA as a promisingly safe and effective ...
Huixiao Wu   +20 more
wiley   +1 more source

Analisis Faktor-Faktor yang Berhubungan dengan Kinerja Balai Pengobatan Gigi Puskesmas di Kabupaten Rembang Tahun 2011 [PDF]

open access: yes, 2012
Universitas Diponegoro Program Pascasarjana Program Magister Ilmu Kesehatan Masyarakat Konsentrasi Administrasi dan Kebijakan Kesehatan 2012 ABSTRAK Sigit Armunanto Analisis Faktor-Faktor yang Berhubungan dengan Kinerja Balai Pengobatan Gigi ...

core  

Discovery of a Novel and Potent Kir4.1 Inhibitor as a Safe and Rapid‐Onset Antidepressant Agent in Mice

open access: yesAdvanced Science, EarlyView.
The preferred derivative JX3212 demonstrates strong inhibitory activity against Kir4.1 with favorable druggability and shows significant antidepressant efficacy in vivo. Abstract Major depressive disorder is a serious psychiatric disorder for which novel and fast‐acting antidepressants are required.
Sisi Wang   +15 more
wiley   +1 more source

Cinnamic‐Hydroxamic‐Acid Derivatives Exhibit Antibiotic, Anti‐Biofilm, and Supercoiling Relaxation Properties by Targeting Bacterial Nucleoid‐Associated Protein HU

open access: yesAdvanced Science, EarlyView.
Cinnamic‐hydroxamic‐acid derivatives (CHADs) are identified as novel inhibitors of the bacterial nucleoid‐associated protein HU, exhibiting potent antibacterial, anti‐biofilm (both inhibition and eradication), and DNA relaxation (anti‐supercoiling) activities. Moreover, CHADs demonstrate strong synergistic effects with multiple antibiotics.
Huan Chen   +22 more
wiley   +1 more source

Final report: refugee oral health sector capacity building project [PDF]

open access: yes
This report develops new resources that support the Victorian public oral health sector\u27s clients of refugee and asylum seeker backgrounds.Summary: The first key outcome of the project was the development of new resources that support the Victorian ...
Thuy Nguyen
core  

A Critical Literature Synthesis of Low-Income Oral Health Disparities in the United States and Interventions for Improved Access to Care [PDF]

open access: yes, 2011
Over a decade ago the United States Surgeon General released a report about oral health in America which highlighted the disparities that exist between high and low-income populations.
Lubiejewski, Sarah
core  

TMEM131‐Mediated Soluble TRAIL Triggered Type II Alveolar Epithelial Cell Senescence in Radiation‐Induced Lung Injury

open access: yesAdvanced Science, EarlyView.
TMEM131 recruits the COPII complex to accelerate TRAIL transportation from endoplasmic reticulum to Golgi apparatus, and promotes soluble TRAIL secretion. TRAIL inhibits mitophagy and induces senescence through DR5 receptor in type II alveolar epithelial cells, ultimately driving radiation‐induced lung injury (RILI) progression.
Linzhi Han   +10 more
wiley   +1 more source

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