Results 171 to 180 of about 22,992,515 (298)

Salivary Citrate Deficiency Defines an Endogenous Dentin Remineralization Failure State Through Glandular MT1/2‐Zn2+‐ACO2 Dysregulation

Advanced Science, EarlyView.
Salivary citrate deficiency in early‐stage Sjögren's syndrome accompanies impaired dentin remineralization despite preserved salivary flow and mineral availability. Matched‐ion experiments reveal disrupted mineral organization and reduced dentin recovery at disease‐associated citrate levels.
Ran You, Wenhui Wang, Franklin R. Tay, Haotian Dong, Mutong Wei, Ruoyun Wu, Xin Song, Chen Chen, Haifeng Xie   +8 more
wiley   +1 more source

Association of Oral Health Literacy and Oral Health Knowledge with Risk Behaviors and Self-Rated Oral Health Among Chinese Dental Patients: A Hospital-Based Cross-Sectional Study in Guangzhou. [PDF]

Healthcare (Basel)
Yu J, Ji Z, Jiang R, Islam R, Li X, Nie E.   +5 more
europepmc   +1 more source

Lactylation of HSC70 Impairs Chaperone‐Mediated Autophagy to Promote Pyrin Inflammasome‐Dependent PANoptosis in Macrophages During Sepsis

Advanced Science, EarlyView.
In sepsis, lactate accumulation drives HSC70 K561 lactylation, which impairs chaperone‐mediated autophagy and blocks CUX1 degradation. Accumulated CUX1 transcriptionally upregulates Pyrin, triggering PANoptosis in macrophages and exacerbating inflammatory storm and organ injury.
Ying Chen, Yan Zhang, Pei Wang, Jiamin Ma, Xinru Zhao, Yi Li, Zhenghao Deng, Xueqing Meng, Jiali Zhu, Liangfang Yao, Jinbao Li   +10 more
wiley   +1 more source

Nursing-Led Oral Health Literacy Intervention and Changes in Dental Anxiety and Oral Health Behaviours Among Geriatric Patients With Dental Diseases: A Non-Randomized One-Group Pretest-Posttest Study. [PDF]

Nurs Open
Gamaa ARA, Atta MHR, Elsehrawy MG, AbouZeid NAA, Alfayomy NAM.   +4 more
europepmc   +1 more source

A Citrulline‐Functionalized Patch Coordinates Macrophage NRF2 Signaling and Arginine Metabolism for Tendon‐to‐Bone Repair

Advanced Science, EarlyView.
A locally implanted patch combines citrulline‐functionalized carbon dots, a thioketal‐containing membrane coating from tendon‐derived stem cells, and aligned core–shell fibers. In macrophages, the patch reduces inflammatory markers and enhances antioxidant signaling through nuclear factor erythroid 2‐related factor 2 (NRF2); in rats and rabbits, it ...
Yuhao Yu, Wencai Liu, Xinyue Yang, Hanzhe Zhang, Hui Xu, Xin Wang, Weimin Lin, Xiping Jiang, Chenrui Yuan, Yifei Wang, Weilin Yu, Yamin Li, Wei Song, Yaohua He   +13 more
wiley   +1 more source

Parent-Reported Oral Health Status and Dental Care Habits in Primary Schoolchildren: A Cross-Sectional Study. [PDF]

Children (Basel)
Dumitrașcu LC, Vacaru RP, Sfeatcu RI, Condurache IA, Vinereanu A.   +4 more
europepmc   +1 more source

Single‐Cell Map of Early Lung Adenocarcinoma Uncovers Invasion‐Associated Tertiary Lymphoid Structures

Advanced Science, EarlyView.
Early thoracic lesions are already heavily infiltrated by immune cells, yet these infiltrates largely consist of bystander T lymphocytes within an immunosuppressive microenvironment. Pathological invasion is strikingly associated with the neogenesis of T/B cell‐rich TLSs that predominantly remain immature.
Pengfei Ma, Chunming He, Mei‐Chun Cai, Jie Wu, Haijiao Lu, Shichao Zhou, Zhenfeng Zhang, Qing Zhang, Yunqing Chen, Jingyu Zang, Kaiyan Ye, Yu Shu, Chee Wai Chua, Hui Li, Yun Fan, Jing Wang, Zhuang Yu, Xinying Xue, Xiaojing Zhao, Guanglei Zhuang, Yujie Fu   +20 more
wiley   +1 more source

Global perspectives on orofacial pain specialization and training. [PDF]

J Taibah Univ Med Sci
Al-Harthy M, Aljohani K.
europepmc   +1 more source

LFA‐1‐Engineered Extracellular Vesicles Deliver CD59 to Protect Endothelial Integrity in Acute Lung Injury

Advanced Science, EarlyView.
LFA‐1‐engineered extracellular vesicles preferentially target pulmonary endothelium and deliver CD59, thereby inhibiting membrane attack complex formation, preserving vascular integrity, and attenuating acute lung injury. This strategy reveals a targeted approach for protecting the pulmonary vasculature from complement‐mediated damage.
Yin Zhu, Shravani Etrouth, Payaningal R. Somanath, S. Priya Narayanan, Yutao Liu, Xiaoyun Wang, Duo Zhang   +6 more
wiley   +1 more source

Incident and Adverse-Event Reporting in Undergraduate Dental Education: A Scoping Review of Educational Evidence, Curricular Integration, Perceptions, and Barriers. [PDF]

Dent J (Basel)
Padmanabhan V, Brown M, Islam MS, Hashim NT, Rahman MM.   +4 more
europepmc   +1 more source