Results 151 to 160 of about 6,640,377 (362)

Next‐generation proteomics improves lung cancer risk prediction

open access: yesMolecular Oncology, EarlyView.
This is one of very few studies that used prediagnostic blood samples from participants of two large population‐based cohorts. We identified, evaluated, and validated an innovative protein marker model that outperformed an established risk prediction model and criteria employed by low‐dose computed tomography in lung cancer screening trials.
Megha Bhardwaj   +4 more
wiley   +1 more source

Determinants of Public Health Outcomes: A Macroeconomic Perspective [PDF]

open access: yes
This paper investigates the nature of the aggregate production function of health services. We build a model to analyze the role of public policy in determining social health outcomes, taking into account households choices concerning education, health ...
Francesco Ricci, Marios Zachariadis
core  

The effect of a cardiovascular risk factor education program on health behaviors of selected school age children [PDF]

open access: yes, 1987
This study, using a quasi-experimental design, was conducted to explore the effect of a cardiovascular risk factor education program on the health behaviors of a group of fifth grade children.
Tuck, Terry M., Williams, Sharon K.
core   +1 more source

Effective therapeutic targeting of CTNNB1‐mutant hepatoblastoma with WNTinib

open access: yesMolecular Oncology, EarlyView.
WNTinib, a Wnt/CTNNB1 inhibitor, was tested in hepatoblastoma (HB) experimental models. It delayed tumor growth and improved survival in CTNNB1‐mutant in vivo models. In organoids, WNTinib outperformed cisplatin and showed enhanced efficacy in combination therapy, supporting its potential as a targeted treatment for CTNNB1‐mutated HB.
Ugne Balaseviciute   +17 more
wiley   +1 more source

Health and physical education 2013 [PDF]

open access: yes
In 2013 the National Monitoring Study of Student Achievement assessed student achievement in two learning areas of the New Zealand Curriculum–health and physical education, and mathematics and statistics.
Educational Assessment Research Unit (Otago)   +1 more
core  

Pengaruh Health Education Mengenai Penyakit Hipertensi Pada Lansia Yang Tinggal Di Panti Jompo [PDF]

open access: yes, 2018
Hipertensi masih menjadi permasalahan kesehatan pada kelompok lanjut usia. Sebagai hasil dari pembangunan yang pesat dan taraf hidup yang sejahtera serta pelayanan kesehatan dapat meningkatkan umur harapan hidup, sehingga jumlah lanjut usia bertambah ...
Firnawati, F. (Firnawati)   +3 more
core  

Exploiting metabolic adaptations to overcome dabrafenib treatment resistance in melanoma cells

open access: yesMolecular Oncology, EarlyView.
We show that dabrafenib‐resistant melanoma cells undergo mitochondrial remodeling, leading to elevated respiration and ROS production balanced by stronger antioxidant defenses. This altered redox state promotes survival despite mitochondrial damage but renders resistant cells highly vulnerable to ROS‐inducing compounds such as PEITC, highlighting redox
Silvia Eller   +17 more
wiley   +1 more source

LINC01116, a hypoxia‐lncRNA marker of pathological lymphangiogenesis and poor prognosis in lung adenocarcinoma

open access: yesMolecular Oncology, EarlyView.
The LINC01116 long noncoding RNA is induced by hypoxia and associated with poor prognosis and high recurrence rates in two cohorts of lung adenocarcinoma patients. Here, we demonstrate that besides its expression in cancer cells, LINC01116 is markedly expressed in lymphatic endothelial cells of the tumor stroma in which it participates in hypoxia ...
Marine Gautier‐Isola   +12 more
wiley   +1 more source

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