Results 151 to 160 of about 6,730,818 (347)

In vitro models of cancer‐associated fibroblast heterogeneity uncover subtype‐specific effects of CRISPR perturbations

open access: yesMolecular Oncology, EarlyView.
Development of therapies targeting cancer‐associated fibroblasts (CAFs) necessitates preclinical model systems that faithfully represent CAF–tumor biology. We established an in vitro coculture system of patient‐derived pancreatic CAFs and tumor cell lines and demonstrated its recapitulation of primary CAF–tumor biology with single‐cell transcriptomics ...
Elysia Saputra   +10 more
wiley   +1 more source

Effect of Health Education on Maternal Behaviors and Pediatric Burn Prevention

open access: yesJournal of Pediatrics Review, 2019
Background: One of the important indicators of development and health in countries is the mortality rate of children under the age of 5 years. In recent years, the mortality rate has dropped below the age of 5, but is still higher in developing countries.
Azam Geravandi, Shahnaz Maleki
doaj  

A Revised Curriculum Tool for Assessing Cultural Competency Training (TACCT) in Health Professions Education

open access: diamond, 2009
Désirée Lie   +7 more
openalex   +1 more source

Effect of chemotherapy on passenger mutations in metastatic colorectal cancer

open access: yesMolecular Oncology, EarlyView.
Changes in passenger mutation load and predicted immunotherapy response after chemotherapy treatment. Tumor cells rich with passenger mutations have increased sensitivity to chemotherapy. Correlation of passenger mutations with neoantigen load suggests highly mutated clones promote a more effective response to immunotherapy, and therefore, first‐line ...
Marium T. Siddiqui   +6 more
wiley   +1 more source

The Effect of education based on Awareness and Performance of hospitals service personnel about protective behaviors against the harmful effects of detergents and disinfectants

open access: yesSavād-i Salāmat, 2017
Background and objective: The individual protective behaviors have essential role in prevention or decrease the incidence of the harmful effects of detergents.
Elham Damani   +5 more
doaj  

Role of Faculty Development Programs in Medical Education at the University of Zimbabwe College of Health Sciences, Zimbabwe

open access: gold, 2018
Antony Matsika   +7 more
openalex   +2 more sources

Dual targeting of RET and SRC synergizes in RET fusion‐positive cancer cells

open access: yesMolecular Oncology, EarlyView.
Despite the strong activity of selective RET tyrosine kinase inhibitors (TKIs), resistance of RET fusion‐positive (RET+) lung cancer and thyroid cancer frequently occurs and is mainly driven by RET‐independent bypass mechanisms. Son et al. show that SRC TKIs significantly inhibit PAK and AKT survival signaling and enhance the efficacy of RET TKIs in ...
Juhyeon Son   +13 more
wiley   +1 more source

Education and Health: Insights from International Comparisons [PDF]

open access: yes
In this review we synthesize what is known about the relationship between education and health. A large number of studies from both rich and poor countries show that education is associated with better health.
Adriana Lleras-Muney, David M. Cutler
core  

Molecular characterisation of human penile carcinoma and generation of paired epithelial primary cell lines

open access: yesMolecular Oncology, EarlyView.
Generation of two normal and tumour (cancerous) paired human cell lines using an established tissue culture technique and their characterisation is described. Cell lines were characterised at cellular, protein, chromosome and gene expression levels and for HPV status.
Simon Broad   +12 more
wiley   +1 more source

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