Results 241 to 250 of about 6,749,359 (294)

YIPFα1A expression is regulated by multilayered molecular mechanisms

FEBS Open Bio, EarlyView.
YIPFα1A, a five‐pass Golgi protein, is regulated at multiple layers. (1) Rare‐codon enrichment drives translation‐coupled mRNA decay. (2) A proximal 3′‐UTR element stabilizes mRNA. (3) A distal 3′‐UTR element included by alternate poly(A) site usage represses translation, which can be overridden by the proximal 3′‐UTR element.
Tokio Takaji, Yurika Nakanishi, Nobuhiro Nakamura   +2 more
wiley   +1 more source

TikTok as a Source of Information on Temporomandibular Disorders: Reliable Health Education or Misinformation? [PDF]

J Clin Exp Dent
Dias Pereira Calças MA, Pinheiro de Souza CS, Andrade SG, Spadon-Brito LG, Mélo AM, Melchior MO, Mazzi-Chaves JF, Magri LV.   +7 more
europepmc   +1 more source

Identifying transcription factors controlling the basal expression of human MRP4 highlights a substantial role for Sp1

FEBS Open Bio, EarlyView.
The MRP4 transporter exports several drugs and signaling molecules. Here, we identified key promoter elements regulating basal MRP4 expression. Using reporter assays, we defined a conserved region with essential Sp1 and contributory Ets sites, which controlled basal MRP4 expression.
Debora Singer, Angelique Kragl, Katrin Ziems, Juliane Glaubitz, Sophie Grammbauer, Susanne Hildebrandt, Mladen V. Tzvetkov, Gabriele Jedlitschky   +7 more
wiley   +1 more source

Research on health education and health promotion during the process of schistosomiasis elimination III new approaches for student health education. [PDF]

PLoS Negl Trop Dis
Zhang J, Lin D, Hu F, Li D, Chen J, Xie H, Li Y, Ding S.   +7 more
europepmc   +1 more source

Pharmacological inhibition of the PERK pathway modulates hepatocellular carcinoma growth and immune signaling

FEBS Open Bio, EarlyView.
Pharmacological inhibition of PERK in a DEN‐induced mouse model of liver cancer does not reduce tumor burden but alters cellular stress signaling. Despite blocking PERK activity, downstream stress responses, including CHOP expression, remain active, suggesting compensatory mechanisms within the unfolded protein response that may influence tumor ...
Ada Lerma‐Clavero, Maria Kopsida, Nathalie Arendt, Hans Lennernäs, Markus Sjöblom, Femke Heindryckx   +5 more
wiley   +1 more source

Student-Oriented Competency Building Module: Implications for the Improvement of Global Health Education. [PDF]

China CDC Wkly
Chen C, Chen H, Wang X, Ding W, Yang J, Cai Y.   +5 more
europepmc   +1 more source

Early‐life high‐fat diet exposure increases Achilles tendon stiffness and induces transcriptomic alterations

FEBS Open Bio, EarlyView.
Early‐life exposure to a high‐fat diet altered intact Achilles tendons in rat offspring, making them thinner, stiffer, and molecularly distinct even without injury. These findings suggest that developmental high‐fat diet exposure may impair tendon quality and increase susceptibility to mechanical overload or tendon injury later in life.
Heyong Yin, Ziyang Yuan, Wenli Jiang, Ai Guo   +3 more
wiley   +1 more source

Competencies and pedagogical foundations for faculty development in interprofessional health education: a scoping review. [PDF]

Rev Esc Enferm USP
Leite DR, Carneiro PS, Mininel VA, Rossit RAS, Leonello VM, Gonçalves GCS, Silva JAMD.   +6 more
europepmc   +1 more source

Culturally Adapted Mental Health Education Programs for Migrant Populations: A Scoping Review. [PDF]

Int J Environ Res Public Health
Thayyilayil SA, Yohani S, Cyuzuzo L, Kennedy M, Salami B.   +4 more
europepmc   +1 more source