Results 141 to 150 of about 4,459,566 (199)

Circular RNA expression landscapes in myelodysplastic neoplasms: Associations with mutational signatures and disease progression

Molecular Oncology, EarlyView.
In this explorative study, the abundance of circular RNA molecules in bone marrow stem cells was found to be elevated in patients with high‐risk myelodysplastic neoplasms, and to be associated with an increased risk of progression to acute myeloid leukemia.
Eileen Wedge, Morten Tulstrup, Gabriele Todisco, Pedro Moura, Christophe Côme, Jakob Werner Hansen, Jakob Schmidt Jespersen, Balthasar Schlotmann, Maria Creignou, Mette Dahl, Claudia Schöllkopf, Klas Raaschou‐Jensen, Krister Wennerberg, Bo Porse, Joachim Weischenfeldt, Eva Hellström‐Lindberg, Lasse Sommer Kristensen, Kirsten Grønbæk   +17 more
wiley   +1 more source

Telenursing in mental health: effect on anxiety symptoms and alcohol consumption during the COVID-19 pandemic. [PDF]

Rev Lat Am Enfermagem, 2023
Vargas D, Ramírez EGL, Pereira CF, Oliveira SR.   +3 more
europepmc   +1 more source

Subtype‐specific enhancer RNAs define transcriptional regulators and prognosis in breast cancers

Molecular Oncology, EarlyView.
This study employed machine learning methodologies to perform the subtype‐specific classification of RNA‐seq data sets, which are mapped on enhancers from TCGA‐derived breast cancer patients. Their integration with gene expression (referred to as ProxCReAM eRNAs) and chromatin accessibility profiles has the potential to identify lineage‐specific and ...
Aamena Y. Patel, Peyman Zarrineh, Nathnael T. Tuffa, Jigar H. Sheth, Sumitra Mohan, Mudassar Iqbal, Sankari Nagarajan   +6 more
wiley   +1 more source

Detection of genome instability by 53BP1 expression as a long-lasting health effect in human epidermis surrounding radiation-induced skin cancers. [PDF]

J Radiat Res
Matsuda K, Kurohama H, Kuwatsuka Y, Iwanaga A, Murota H, Nakashima M.   +5 more
europepmc   +1 more source

Dimethyl fumarate combined with cisplatin at subcytotoxic doses sensitizes cervical cancer toward ferroptosis and apoptosis through GSH restriction and p53 (re)activation

Molecular Oncology, EarlyView.
Dimethyl fumarate (DMF) reduces growth of HPV‐positive cervical cancer spheroids and induces ferroptosis in cervical cancer cells via blocking SLC7A11/Glutathione (GSH) axis. Combination of subcytotoxic doses of DMF and cisplatin (CDDP) further suppresses spheroid growth and drives cell death in 2D culture models.
Carolina Punziano, Giuseppina Minopoli, Simona Romano, Laura Marrone, Katia Aquilano, Maria Lina Tornesello, Raffaella Faraonio   +6 more
wiley   +1 more source

Health effect of public sports services and public health services: empirical evidence from China. [PDF]

Front Public Health
Cao L, Cai J, Gong Y, Bao Q, Hu J, Tang N.   +5 more
europepmc   +1 more source

Reduced Bone Mineral Density in Children: Another Potential Health Effect of PFAS. [PDF]

Environ Health Perspect, 2020
Schmidt CW.
europepmc   +1 more source

Network divergence analysis identifies adaptive gene modules and two orthogonal vulnerability axes in pancreatic cancer

Molecular Oncology, EarlyView.
Tumors contain diverse cellular states whose behavior is shaped by context‐dependent gene coordination. By comparing gene–gene relationships across biological contexts, we identify adaptive transcriptional modules that reorganize into distinct vulnerability axes.
Brian Nelson, Lyanne Delgado‐Coka, Natalia Marchenko, Luisa F. Escobar‐Hoyos, Kenneth R. Shroyer, Alisa Yurovsky, Trey Ideker, Gábor Balázsi, Thomas MacCarthy, Scott Powers   +9 more
wiley   +1 more source

A Review of the Distribution and Health Effect of Organophosphorus Flame Retardants in Indoor Environments. [PDF]

Toxics
Song X, Zhu S, Hu L, Chen X, Zhang J, Liu Y, Bu Q, Ma Y.   +7 more
europepmc   +1 more source

The impact of measurement error in modeled ambient particles exposures on health effect estimates in multilevel analysis: A simulation study. [PDF]

Environ Epidemiol, 2020
Samoli E, Butland BK, Rodopoulou S, Atkinson RW, Barratt B, Beevers SD, Beddows A, Dimakopoulou K, Schwartz JD, Yazdi MD, Katsouyanni K.   +10 more
europepmc   +1 more source