Results 91 to 100 of about 843,910 (299)

Dendrimers Improve Apolipoprotein Nanoparticle mRNA Delivery to Immune Cells

Advanced Materials, EarlyView.
Apolipoprotein nanoparticle (aNP) platform technology efficiently delivers RNA to immune cells following systemic administration. Here, it is demonstrated that incorporating polyvalent ionizable cationic dendrimers in aNPs enables robust mRNA complexation and functional delivery.
Mirre M. Trines, Daniek Hoorn, Stijn R.J. Hofstraat, Robby C. Zwolsman, Tom Anbergen, Iris Versteeg, Yuri van Elsas, Jeroen Deckers, Merel M.A. Hendrikx, Teun Kleuskens, Youssef B. Darwish, Gijs W.B. Ros, Sjoerd F. Dijkstra, Bram Priem, Matt Timmers, P. Michel Fransen, Maarten J. Pouderoijen, Bas F.M. de Waal, E.W. Meijer, Thijs J. Beldman, Yohana C. Toner, Ewelina Kluza, Willem J.M. Mulder, Henk M. Janssen, Roy van der Meel   +24 more
wiley   +1 more source

Molecular Nanosolids Generation by Vapor Jet Desublimation

Advanced Materials, EarlyView.
A single‐step, solvent‐free approach to fabricate nanoparticles of small organic molecules is demonstrated, using a nitrogen‐propelled vapor jet, enabling tunable particle morphology and crystallinity. Pharmaceutical, flavoring, dyeing and electronics‐relevant molecules are used, demonstrating process generalizability.
Chao Huang, Eva Katharine Pontrelli, Jae Wan Lee, Binyu Wang, Ganlin Chen, Tatiane Cogo Machado, Hemanth Maddali, Benjamin De Chazal, Anish Tuteja, Ronald G. Larson, Naír Rodríguez‐Hornedo, Max Shtein   +11 more
wiley   +1 more source

The influence of gender-based perceptions on females joining a bachelor of medicine, bachelor of surgery in Rwanda

BMC Medical Education
Through progressive policies, Rwanda has made significant strides in promoting girls’ education and empowerment. However, female enrollment in Bachelor of Medicine and Bachelor of Surgery (MBBS) programs remains disproportionately low.
Tsion Yohannes Waka, Deborah Umucyo, Arlene Nishimwe, Abigail J. Yoon, Kara L. Neil   +4 more
doaj   +1 more source

Exploring drivers and prevention strategies for sexual violence among adolescent girls and young women in Kicukiro, Rwanda

Frontiers in Reproductive Health
IntroductionSexual violence against adolescent girls and young women (AGYW) is a pervasive issue globally, with particularly high prevalence in sub-Saharan Africa.
Wongani Patricia Kawonga, Sam M. Livingstone, Augustine Ndaimani, Jean Pierre Sibomana, Tsion Yohannes Waka, Maxwell Mhlanga, Andrew Mclellan   +6 more
doaj   +1 more source

Creating a center for global health at the University of Wisconsin-Madison. [PDF]

, 2008
Globalization, migration, and widespread health disparities call for interdisciplinary approaches to improve health care at home and abroad. Health professions students are pursuing study abroad in increasing numbers, and universities are responding with
Baumann, Linda, Bousquet, Gilles, Brown, Lori DiPrete, Conway, James, Easterday, BC, Haq, Cynthia, Kraus, Connie, Olsen, Christopher W   +7 more
core   +1 more source

An Anti‐Myd88 Peptide Synergistically Enhances the Anti‐Inflammatory Effects of Extracellular Vesicles from Naïve Umbilical Cord MSC or HEK293F CD24 Overexpressing Cells

Advanced Materials Interfaces, EarlyView.
This study confirms that extracellular vesicles (EVs) derived from mesenchymal stem cells (MSCs) or HEK293F cells overexpressing CD24 have anti‐inflammatory effects in macrophages and monocytes. Further loading either of these EVs with an anti‐Myd88 peptide synergistically enhanced the anti‐inflammatory effects of the EVs.
Burçin İrem Abas, Markus Bergqvist, Lijuan Yu, Yi Wang, Mario Gimona, Kyong‐su Park, Jan Lötvall   +6 more
wiley   +1 more source

Cross-country analysis of contextual factors and implementation strategies in under-5 mortality reduction in six low- and middle-income countries 2000–2015

BMC Pediatrics
Background The Exemplars in Under-5 Mortality (U5M) was a multiple cases study of how six low- and middle-income countries (LMICs), Bangladesh, Ethiopia, Nepal, Peru, Rwanda, and Senegal, implemented health system-delivered evidence-based interventions ...
Agnes Binagwaho, Amelia VanderZanden, Patricia J. Garcia, Fauzia Akhter Huda, Mahesh Maskey, Mohamadou Sall, Felix Sayinzoga, Raj Kumar Subedi, Alula M. Teklu, Kateri Donahoe, Miriam Frisch, Jovial Thomas Ntawukuriryayo, Kelechi Udoh, Lisa R. Hirschhorn   +13 more
doaj   +1 more source

Maintaining Delivery of Evidence-Based Interventions to Reduce Under-5 Mortality During COVID-19 in Rwanda: Lessons Learned through Implementation Research

Annals of Global Health
Background: The COVID-19 pandemic resulted in drops in access to and availability of a number of evidence-based interventions (EBIs) known to reduce under-5 mortality (U5M) across a wide range of countries, including Rwanda.
Alemayehu Amberbir, Felix Sayinzoga, Kedest Mathewos, Jovial Thomas Ntawukuriryayo, Amelia VanderZanden, Lisa R Hirschhorn, Agnes Binagwaho   +6 more
doaj   +1 more source

Can equity be included in a performance evaluation system? Some evidences from the tuscan health care system [PDF]

Objectives. Can Equity be included in a performance evaluation system? In Italy, the Tuscan Region has tested and now is adopting an integrated model for performance measurement to which the regional administration, the local health authorities, and ...
Sabina Nuti, Sara Barsanti
core  

Breaking the Barriers to Specialty Care: Practical Ideas to Improve Health Equity and Reduce Cost - Striving for Equity in Specialty Care [PDF]

, 2016
Tremendous health outcome inequities remain in the U.S. across race and ethnicity, gender and sexual orientation, socio-economic status, and geography—particularly for those with serious conditions such as lung or skin cancer, HIV/AIDS, or cardiovascular
Chris Carlson, Jared Sholk, Jennifer Nanni, Kyle Peterson, Lauren A. Smith, Neeraja Bhavaraju   +5 more
core