Results 111 to 120 of about 843,910 (299)

A Compartmentalized Joint‐on‐chip (JoC) Model to Unravel the Contribution of Cartilage and Synovium to Osteoarthritis Pathogenesis

open access: yesAdvanced Science, EarlyView.
A compartmentalized joint‐on‐chip (JoC) platform is here developed, modelling the interactions between cartilage and synovium in osteoarthritis (OA). Using independent culture and mechanical/biochemical stimulation, the JoC revealed how inflammation and mechanical damage drive mutual tissue changes.
Cecilia Palma   +6 more
wiley   +1 more source

Demand for family planning satisfied with modern methods among sexually active women in low- and middle-income countries: who is lagging behind?

open access: yesReproductive Health, 2018
Background Family planning is key for reducing unintended pregnancies and their health consequences and is also associated with improvements in economic outcomes. Our objective was to identify groups of sexually active women with extremely low demand for
Fernanda Ewerling   +5 more
doaj   +1 more source

U.S. Variations in Child Health System Performance: A State Scorecard [PDF]

open access: yes, 2008
Ranks state child health systems on thirteen measurements of five dimensions: access, quality, costs, equity, and potential to lead healthy lives.
Edward L. Schor   +2 more
core  

A Comprehensive Lateral Flow Strip Assay for On‐Site mRNA Vaccine Quality Control in Decentralized Manufacturing

open access: yesAdvanced Science, EarlyView.
A rapid, portable lateral flow strip assay for on‐site mRNA quality control is developed, enabling sequence‐independent analysis of 5' capping, integrity, and LNPs encapsulation efficiency. This cost‐effective method offers real‐time stability monitoring, reduced sample requirements, and comparable accuracy to standard techniques, enhancing ...
Dengwang Luo   +9 more
wiley   +1 more source

Why Not the Best? Results From the National Scorecard on U.S. Health System Performance, 2008 [PDF]

open access: yes, 2008
Assesses the U.S. healthcare system's average performance as measured by thirty-seven indicators of health outcomes, quality, access, efficiency, and equity.

core  

Tumor Intrinsic METTL5 Modulates ATF4 Translation to Prevent T Cell‐Induced Ferroptosis in Ovarian Cancer

open access: yesAdvanced Science, EarlyView.
An integrative analysis combining in vitro genome‐wide immune screens, in vivo ICB screens, and clinical data mining identifies METTL5 as a key tumor‐intrinsic immune factor. Mechanistic studies further reveal the importance of the METTL5‐ATF4‐SLC7A11/SLC3A2‐ferroptosis axis in modulating antitumor immune responses. These findings highlight METTL5 as a
Jiakai Hou   +30 more
wiley   +1 more source

Aiming Higher: Results From a State Scorecard on Health System Performance [PDF]

open access: yes, 2007
Assesses state variation across key dimensions of health system performance -- access, quality, avoidable hospital use and costs, equity, and healthy lives -- and assigns overall state rankings as well as ranks on each ...
Cathy Schoen   +4 more
core  

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