Results 51 to 60 of about 843,910 (299)

Mentorship effect on healthcare providers' adherence to postpartum haemorrhage guidelines and maternal outcomes in Rwanda. A quasi-experimental study.

NSC Nursing
Background: Postpartum hemorrhage (PPH) is a leading cause of maternal morbidity and mortality worldwide. Effective management of PPH heavily relies on adherence to clinical guidelines.
Benjamin David Habikigeni , Arlette Bizimana, Maxwell Mhlanga, Tsion Yohannes   +3 more
doaj   +1 more source

Central Dysmyelination in SSADH‐Deficient Humans and Mice

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objectives Succinic semialdehyde dehydrogenase deficiency (SSADHD) is an inherited metabolic disorder characterized by an accumulation of γ‐aminobutyric (GABA). In addition to its synaptic role as an inhibitory neurotransmitter, GABA also plays an important role in myelination.
Itay Tokatly Latzer, Henry H. C. Lee, Edward Yang, Cesar Alves, Mariarita Bertoldi, Caitlyn Fung, Spencer V. Steele, Eren Kule, Zijie Jin, Alexander Rotenberg, Jean‐Baptiste Roullet, Phillip L. Pearl   +11 more
wiley   +1 more source

Understanding rapid implementation from discovery to scale: Rwanda’s implementation of rotavirus vaccines and PMTCT in the quest to reduce under-5 mortality

BMC Pediatrics
Background Over the last eight decades, many evidence-based interventions (EBIs) have been developed to reduce amenable under-5 mortality (U5M). Implementation research can help reduce the lag between discovery and delivery, including as new EBIs emerge,
Felix Sayinzoga, Lisa R. Hirschhorn, Jovial Thomas Ntawukuriryayo, Caroline Beyer, Kateri B. Donahoe, Agnes Binagwaho   +5 more
doaj   +1 more source

Durability of Response to B‐Cell Maturation Antigen‐Directed mRNA Cell Therapy in Myasthenia Gravis

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective We report the 12‐month follow‐up outcomes from a Phase 2 clinical trial (NCT04146051) evaluating Descartes‐08, a BCMA‐directed RNA chimeric antigen receptor T‐cell (rCAR‐T) therapy for refractory generalized myasthenia gravis (MG).
Nizar Chahin, Gregory Sahagian, Marc H. Feinberg, C. Andrew Stewart, Christopher M. Jewell, Metin Kurtoglu, Miloš D. Miljković, Tuan Vu, Tahseen Mozaffar, James F. Howard Jr, the MG‐001 Study Group   +10 more
wiley   +1 more source

Evidence-based universal health coverage interventions delivery in infectious disease of poverty elimination and eradication

Infectious Diseases of Poverty
The recent 78th United Natiions General Assembly (UNGA) declaration relaunched a new health priority and political commitment in accelerating Universal Health Coverage (UHC), adopted by the United Nations (UN) in 2015 and are intended to be met by 2030 ...
Ernest Tambo, Chidiebere E. Ugwu, Amberbir Alemayehu, Anil Krishna, Agnes Binagwaho   +4 more
doaj   +1 more source

An intersectional analysis of the composite index of anthropometric failures in India

International Journal for Equity in Health, 2021
Background Nutritional inequality in India has been estimated typically using stunting, wasting and underweight separately which hide the overall magnitude and severity of undernutrition.
Sabu Ulahannan Kochupurackal, Yogish Channa Basappa, Sangeetha Joice Vazhamplackal, Prashanth N Srinivas   +3 more
doaj   +1 more source

Longitudinal Relationship Between Pain and Depression in People With Inflammatory Arthritis: A Narrative Review

Arthritis Care &Research, EarlyView.
As many patients with inflammatory arthritis (IA) have chronic pain, understanding how to best assess and manage pain in IA is a priority. Comorbid depression is prevalent in adults with IA, affecting 15% to 39% of people. Although pain and depression are thought to be associated in IA, this concept is largely based on cross‐sectional data.
Natasha Cox, Saeed Farooq, Helen Twohig, Ian C. Scott   +3 more
wiley   +1 more source

“An eye-opener:” a qualitative study of a liberal arts approach to medical education

BMC Medical Education
Background Medical educators have underscored the need for medical students to study the larger sociocultural and economic forces that influence health rather than simply basic and clinical sciences; however, previous studies have not evaluated the ...
Abebe Bekele, Denis Regnier, Claire O. Swedberg, Eden Abate Lemu, Christelle Uwantege Giraneza, Elizabeth H. Bradley   +5 more
doaj   +1 more source

Global Health Equity Requires Global Equity

Health Equity, 2023
Many global health challenges are characterized by the inequitable patterning of their health and economic consequences, which are etched along the lines of pre-existing inequalities in resources, power, and opportunity. These links require us to reconsider how we define global health equity, and what we consider as most consequential in its pursuit ...
Nason Maani, Salma M. Abdalla, Catherine K. Ettman, Lily Parsey, Emma Rhule, Pascale Allotey, Sandro Galea   +6 more
openaire   +4 more sources

Global and regional temporal changes in cross‐country inequalities of site‐specific osteoarthritis burden, 1990–2021

Arthritis Care &Research, Accepted Article.
Objective This study examined the global and regional temporal changes in cross‐country inequalities of site‐specific osteoarthritis (OA) burden from 1990 to 2021. Methods Age‐standardized years lived with disability rate for site‐specific OA across 204 countries/territories were obtained from the Global Burden of Diseases Study (GBD) 2021.
Haowei Chen, Lei Si, David J Hunter, Lei Zhang, Zhe‐Sheng Chen, Xiaomeng Wang, Vicky Duong, Zhounan Zhou, Peihua Cao, Han Cen, Su'an Tang, Tianyu Chen, Houjun Xue, Zhaohua Zhu, Changhai Ding   +14 more
wiley   +1 more source