Results 41 to 50 of about 11,933,477 (311)

Emerging experimental and computational methods for studying redox‐regulated structural transitions

open access: yesFEBS Letters, EarlyView.
Redox reactions can reshape proteins and alter how they behave in cells, with important consequences for health and disease. This review explores emerging experimental and computational approaches for discovering these redox‐sensitive protein switches, revealing their structural effects, and predicting their behavior, opening new opportunities to ...
Tasneem Rass   +2 more
wiley   +1 more source

Disease and economic burden for rare diseases in Taiwan: A longitudinal study using Taiwan's National Health Insurance Research Database. [PDF]

open access: yesPLoS ONE, 2018
BACKGROUND:High-cost orphan drugs are becoming increasingly available to treat rare diseases that affect a relatively small population. Little attention has been given to the prevalence of rare diseases and their health-related economic burden in Taiwan.
Jason C Hsu   +5 more
doaj   +1 more source

Trends and outcomes in primary health care expenditures in low-income and middle-income countries, 2000–2017

open access: yesBMJ Global Health, 2021
Introduction As the world responds to COVID-19 and aims for the Sustainable Development Goals, the potential for primary healthcare (PHC) is substantial, although the trends and effectiveness of PHC expenditure are unknown.
Angela E Micah   +10 more
doaj   +1 more source

Data brief from the Circumpolar Health Observatory: Health expenditures [PDF]

open access: yes, 2012
"A basic measure in the international comparison of health care systems is health care expenditures. It provides a glimpse of the health care resources available to, and used by, the various health care agencies." (as cited in ...
Young, T. Kue
core   +1 more source

Prospecting the protein design landscape

open access: yesFEBS Letters, EarlyView.
This review outlines the current state of various protein design approaches. We discuss the current possibilities enabled by recently released tools, highlight future avenues to pursue in protein design, and underscore the crucial role of key databases and resources for successful protein design workflows.
Jakob R. Riccabona   +4 more
wiley   +1 more source

Southern African customs union revenue, public expenditures and HIV/AIDS in BLNS countries

open access: yesSouth African Journal of Economic and Management Sciences, 2014
This study investigates how revenue from the Southern African Customs Union (SACU) common revenue pool affects efforts to contain HIV/AIDS in Botswana, Lesotho, Namibia and Swaziland (BLNS countries).
Harold Ngalawa
doaj   +1 more source

Effects of Air Pollution on Public and Private Health Expenditures in Iran: A Time Series Study (1972-2014) [PDF]

open access: yesJournal of Preventive Medicine and Public Health, 2018
Objectives Environmental pollution is a negative consequence of the development process, and many countries are grappling with this phenomenon.
Pouran Raeissi   +5 more
doaj   +1 more source

Healthcare utilization and expenditures for chronic and acute conditions in Georgia: does benefit package design matter? [PDF]

open access: yes, 2015
BACKGROUND: In 2007 the Georgian government introduced a full state-subsidized Medical Insurance Program for the Poor (MIP) to provide better financial protection and improved access for socially and financially disadvantaged citizens. Studies evaluating
Akaki Zoidze   +7 more
core   +2 more sources

Single‐cell DNA methylation profiling: Technologies, computation, and applications in precision oncology

open access: yesMolecular Oncology, EarlyView.
Single‐cell DNA methylation (scDNAme) profiling maps epimutational clonal evolution, revealing mechanisms of malignancy and therapeutic resistance across diverse cancer types. By providing a high‐resolution landscape of intratumoral heterogeneity, these technologies empower precise patient stratification, guide the development of enhanced ...
Ik Soo Kim
wiley   +1 more source

Predictive and prognostic biomarkers of Bacillus Calmette‐Guérin therapy failure in bladder cancer patients: A systematic review

open access: yesMolecular Oncology, EarlyView.
High‐risk bladder cancer is typically treated with Bacillus Calmette‐Guérin (BCG), but 30–40% of patients relapse. No FDA‐ or CE‐approved biomarkers currently predict or prognosticate BCG failure. We systematically reviewed the literature and identified 72 eligible studies, revealing several promising biomarkers associated with BCG treatment response ...
Rui Ribeiro‐Pereira   +7 more
wiley   +1 more source

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