Results 91 to 100 of about 893,794 (314)
Molecular Oncology, EarlyView.CIN85 is highly expressed in osteosarcoma, particularly in metastatic lesions. Its overexpression increases cell migration and Matrigel invasion, while silencing CIN85 suppresses these behaviors. Transcriptome analysis shows that CIN85 regulates MMP2, COL3A1, and Akt/mTOR signaling. Targeting these pathways reverses CIN85‐induced motility, highlighting
Iryna Horak +10 more
wiley +1 more source
[Reconstructing the relationship in health facilities].
Soins; la revue de reference infirmiere, 2018 Les établissements de santé sont aujourd’hui soumis à des logiques de rentabilité, d’efficacité et de performance qui se heurtent aux valeurs d’aide et d’accompagnement des soignants. Pour maintenir la nécessaire réflexion sur le travail de soin et ses difficultés, les cadres de santé doivent veiller à favoriser et renforcer les relations collégiales ...
openaire +2 more sources
Molecular Oncology, EarlyView.Here, we demonstrate that HS1BP3 interacts with Cortactin through a proline‐rich region (PRR3.1) and show that this interaction, and HS1BP3 itself, promote cancer cell proliferation and invasion. Inhibition of this interaction leads to build‐up of TKS5 in multivesicular endosomes and altered secretion of CD63 and CD9, providing an explanation for the ...
Arja Arnesen Løchen +9 more
wiley +1 more source
Integrated Pharmacy Research and Practice, 2022 Azmeraw Bekele,1,2 Feneti Gemechu,3 Mihret Ayalew2,4 1Social and Administrative Pharmacy Unit, Institute of Health, Jimma University, Jimma, Ethiopia; 2School of Pharmacy, Jimma University, Jimma, Ethiopia; 3Department of Pharmacy, Adama Hospital Medical
Bekele A, Gemechu F, Ayalew M
doaj
Molecular Oncology, EarlyView.Combining osimertinib with the STING agonist ADU‐S100 activates innate and adaptive immunity to overcome the non‐inflamed microenvironment of Egfr‐mutant lung cancer. This combination increases NK and CD8+ T‐cell infiltration, associated with activation of the STING‐IRF3 pathway and local immunogenic cell death.
Jun Nishimura +19 more
wiley +1 more source
Health manpower and health facilities, 1968
Health manpower and health facilities, 1968This second edition of HEALTH RESOURCES STATISTICS, 1968 contains data on health manpower and inpatient health facilities.
core
Pharmacovigilance systems in resource-limited settings: an evaluative case study of Sierra Leone
Journal of Pharmaceutical Policy and Practice, 2019 Few low and middle-income countries (LMIC) have fully operational pharmacovigilance structures, systems and legal framework to collect and collate safety data and evaluate the risks and benefits by active and passive approaches.
Onome T. Abiri, Wiltshire C. N. Johnson
doaj +1 more source
Loss of IGF‐1R impairs DNA‐PKcs recruitment to chromatin leading to defective end‐joining
Molecular Oncology, EarlyView.IGF‐1R promotes radioresistance by facilitating DNA‐PKcs recruitment to chromatin, enabling non‐homologous end‐joining (NHEJ) repair of double‐strand breaks. Inhibition or loss of IGF‐1R disrupts this recruitment to damage sites, driving compensatory reliance on microhomology‐mediated end‐joining (MMEJ) repair.
Matthew O. Ellis +3 more
wiley +1 more source
Kansas State Plan of ... Hospital Construction, 1948 Eight Annual Revision of the Kansas State Plan for Construction of Hospitals and Medical Facilities, 1956 Tenth Annual Revision of the Kansas State Plan for Construction of Hospitals and Medical ...
Kansas Division of Hospital Facilities.
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Evaluation of diphtheria surveillance system in Kaduna State, Nigeria, July 2023 – December 2023
Journal of Public Health in AfricaBackground: The re-emergence of the diphtheria outbreak in Nigeria raises concern about the surveillance system’s capability to detect, prepare for and respond to outbreaks.
Uwaifiokun J. Okhuarobo +8 more
doaj +1 more source