Results 151 to 160 of about 7,977,848 (398)

Objective-Oriented Health Systems Reform

open access: yesHealth Systems & Reform
This paper emphasizes the importance of orienting health system reforms to address underlying system-level performance problems. Too often in practice, the objective-orientation that is stressed in health system frameworks gets lost in relation to ...
Joseph Kutzin   +4 more
doaj   +1 more source

Cell‐free and extracellular vesicle microRNAs with clinical utility for solid tumors

open access: yesMolecular Oncology, EarlyView.
Cell‐free microRNAs (cfmiRs) are small‐RNA circulating molecules detectable in almost all body biofluids. Innovative technologies have improved the application of cfmiRs to oncology, with a focus on clinical needs for different solid tumors, but with emphasis on diagnosis, prognosis, cancer recurrence, as well as treatment monitoring.
Yoshinori Hayashi   +6 more
wiley   +1 more source

Geographic Variation and Health Care Cost Growth: Research to Inform a Complex Diagnosis [PDF]

open access: yes, 2009
Summarizes preliminary findings and discussions from RWJF's Changes in Health Care Financing Organization initiative about the drivers of healthcare costs across states, including sector-specific factors, technology, chronic illness, and ...
Jenny Minott
core  

KRAS and GNAS mutations in cell‐free DNA and in circulating epithelial cells in patients with intraductal papillary mucinous neoplasms—an observational pilot study

open access: yesMolecular Oncology, EarlyView.
This study demonstrates that KRAS and GNAS mutations are more prevalent in patients with resected intraductal papillary mucinous neoplasms (IPMN) compared to those under clinical surveillance. GNAS mutations significantly differ between the two patient cohorts, indicating that their absence may serve as a potential biomarker to support conservative ...
Christine Nitschke   +12 more
wiley   +1 more source

Healthy food financing initiatives: Increasing access to fresh foods in underserved markets [PDF]

open access: yes
The Fresh Food Financing Initiative in Philadelphia serves the financing needs of supermarket operators that plan to operate in underserved communities that may have limited access to affordable, healthy foods.
Matthew Soursourian
core  

The global landscape of country-level health technology assessment processes: A survey among 104 countries

open access: yesHealth Policy Open
To make progress towards universal health coverage (UHC), countries need to be able to develop and implement evidence-informed and inclusive processes for decision-making to inform what services are provided and purchased.
Andrew J. Mirelman   +2 more
doaj  

Cellular liquid biopsy provides unique chances for disease monitoring, preclinical model generation and therapy adjustment in rare salivary gland cancer patients

open access: yesMolecular Oncology, EarlyView.
We quantified and cultured circulating tumor cells (CTCs) of 62 patients with various cancer types and generated CTC‐derived tumoroid models from two salivary gland cancer patients. Cellular liquid biopsy‐derived information enabled molecular genetic assessment of systemic disease heterogeneity and functional testing for therapy selection in both ...
Nataša Stojanović Gužvić   +31 more
wiley   +1 more source

Equity and Health [PDF]

open access: yes
This article raises the problem of equity in the health system in Switzerland. Three dimensions of the concept of equity are taken into consideration: the inequality in the financing of the health system, the inequality in the distri-bution of the state ...
Gaillard, Gabrielle
core  

Circulating tumor DNA (ctDNA) trajectories predict survival in trifluridine/tipiracil‐treated metastatic colorectal cancer patients

open access: yesMolecular Oncology, EarlyView.
The authors applied joint/mixed models that predict mortality of trifluridine/tipiracil‐treated metastatic colorectal cancer patients based on circulating tumor DNA (ctDNA) trajectories. Patients at high risk of death could be spared aggressive therapy with the prospect of a higher quality of life in their remaining lifetime, whereas patients with a ...
Matthias Unseld   +7 more
wiley   +1 more source

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