Results 271 to 280 of about 7,977,848 (398)
TRPM8 levels determine tumor vulnerability to channel agonists
TRPM8 is a Ca2+ permissive channel. Regardless of the amount of its transcript, high levels of TRPM8 protein mark different tumors, including prostate, breast, colorectal, and lung carcinomas. Targeting TRPM8 with channel agonists stimulates inward calcium currents followed by emptying of cytosolic Ca2+ stores in cancer cells.
Alessandro Alaimo+18 more
wiley +1 more source
Tobacco control in the Sustainable Development Goals: a precarious inclusion?
Roy Small+3 more
doaj +1 more source
Leveraging health financing, digital health and self-care approaches to strengthen maternal health journeys in India: perspectives from Assam. [PDF]
Ramesh S+8 more
europepmc +1 more source
Iranian health financing system challenges to promote health outcomes: Qualitative study. [PDF]
Jabbari A+3 more
europepmc +1 more source
health care financing and health systems planning for afghanistan 1992
Maysam Hussain+12 more
openalex +1 more source
The pan‐HDAC inhibitor belinostat increases the expression of the pro‐apoptotic proteins Bim, Puma, and Noxa and induces apoptosis in ovarian cancer cell lines and patient‐derived tumor organoids when used at high concentrations. Moreover, inhibiting the anti‐apoptotic proteins Bcl‐xL or Mcl‐1 sensitizes these preclinical models to the cytotoxic effect
Cécilia Thomine+10 more
wiley +1 more source
Health outcome convergence and the roles of public health financing and governance in Africa. [PDF]
Ndzignat Mouteyica AE, Ngepah NN.
europepmc +1 more source
Quality or financing: what drives design of the health care system? [PDF]
V. McLoughlin
openalex +1 more source
Systematic profiling of cancer‐fibroblast interactions reveals drug combinations in ovarian cancer
Fibroblasts, cells in the tumor environment, support ovarian cancer cell growth and alter morphology and drug response. We used fibroblast and cancer cell co‐culture models to test 528 drugs and discovered new drugs for combination treatment. We showed that adding Vorinostat or Birinapant to standard chemotherapy may improve drug response, suggesting ...
Greta Gudoityte+10 more
wiley +1 more source