Results 81 to 90 of about 684,204 (318)

Reciprocal control of viral infection and phosphoinositide dynamics

open access: yesFEBS Letters, EarlyView.
Phosphoinositides, although scarce, regulate key cellular processes, including membrane dynamics and signaling. Viruses exploit these lipids to support their entry, replication, assembly, and egress. The central role of phosphoinositides in infection highlights phosphoinositide metabolism as a promising antiviral target.
Marie Déborah Bancilhon, Bruno Mesmin
wiley   +1 more source

The SWOT Analysis of the Romanian Health Care System [PDF]

open access: yes
The complexity of the problem the national health care program confronts with and which must be solved through the measures of the respective reform lead to a SWOT analysis, particularly for this reform.
Claudiu CICEA, Cristian BUSU
core  

An intracellular transporter mitigates the CO2‐induced decline in iron content in Arabidopsis shoots

open access: yesFEBS Letters, EarlyView.
This study identifies a gene encoding a transmembrane protein, MIC, which contributes to the reduction of shoot Fe content observed in plants under elevated CO2. MIC is a putative Fe transporter localized to the Golgi and endosomal compartments. Its post‐translational regulation in roots may represent a potential target for improving plant nutrition ...
Timothy Mozzanino   +7 more
wiley   +1 more source

Using a Small Lever to Achieve Big Outcomes in a Devolved Health System: 20 Years of Programa Sumar in Argentina

open access: yesHealth Systems & Reform
Incremental health system transformations towards universal health coverage run the risk of losing sight of the overarching objectives and can lose momentum in the implementation process.
Martin Sabignoso   +2 more
doaj   +1 more source

Econometric estimation of WHO-CHOICE country-specific costs for inpatient and outpatient health service delivery

open access: yesCost Effectiveness and Resource Allocation, 2018
Background Policy makers require information on costs related to inpatient and outpatient health services to inform resource allocation decisions. Methods Country data sets were gathered in 2008–2010 through literature reviews, website searches and a ...
Karin Stenberg   +4 more
doaj   +1 more source

A Cre‐dependent lentiviral vector for neuron subtype‐specific expression of large proteins

open access: yesFEBS Letters, EarlyView.
We designed a versatile and modular lentivector comprising a Cre‐dependent switch and self‐cleaving 2A peptide and tested it for co‐expression of GFP and a 2.8 kb gene of interest (GOI) in mouse cortical parvalbumin (PV+) interneurons and midbrain dopamine (TH+) neurons.
Weixuan Xue   +6 more
wiley   +1 more source

The efficiency of secondary-level hospitals in hard-to-reach and non-hard-to-reach areas in Bangladesh: a data envelopment analysis approach

open access: yesBMC Health Services Research
Background Efficiency in healthcare delivery is crucial for maximizing resource utilization and achieving broader health system objectives, particularly in resource-constrained settings like hard-to-reach (HTR) areas in Bangladesh.
Mohammad Wahid Ahmed   +3 more
doaj   +1 more source

Growing Pains for the Los Angeles Healthy Kids Program: Findings From the Second Evaluation Case Study (Apr 2008) [PDF]

open access: yes, 2008
Evaluates the program to provide health coverage to poor children ineligible for Medi-Cal or Healthy Families in terms of outreach, enrollment, and retention; benefits, service delivery, and access; financing and stability; and program ...
Brigette Courtot   +3 more
core  

By dawn or dusk—how circadian timing rewrites bacterial infection outcomes

open access: yesFEBS Letters, EarlyView.
The circadian clock shapes immune function, yet its influence on infection outcomes is only beginning to be understood. This review highlights how circadian timing alters host responses to the bacterial pathogens Salmonella enterica, Listeria monocytogenes, and Streptococcus pneumoniae revealing that the effectiveness of immune defense depends not only
Devons Mo   +2 more
wiley   +1 more source

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